Výsledky vyhledávání - "G. C. MacDonald"

B cell genotype determines the fine specificity of autoantibody in lpr mice

Autor: V N Kakkanaiah, E S Sobel, G C MacDonald, R L Cheek, P L Cohen, R A Eisenberg

Publikováno v: The Journal of Immunology. 159:1027-1035

Anti-Sm Abs are specific markers of human systemic lupus erythematosus (SLE) and of murine models of this disease. In humans, anti-Sm Abs are mostly IgG1, and in MRL/lpr mice, IgG2a; both are T-dependent isotypes. Other lpr strains, such as B6/lpr, d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab4097e9d8931ec2823b10a25bff2ef6
https://doi.org/10.4049/jimmunol.159.2.1027

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Risk analysis of Unmanned Aerial Vehicle hijacking and methods of its detection

Autor: J. A. Wright, G. C. MacDonald, B. J. Hourican, M. S. Faughnan, M. Srivastava, Yacov Y. Haimes, Zhenyu Guo, Eva Andrijcic, J. C. White

Publikováno v: 2013 IEEE Systems and Information Engineering Design Symposium.

The Federal Aviation Administration (FAA) is in the process of integrating Unmanned Aerial Vehicles (UAVs) into the National Airspace System (NAS) through the Next Generation Air Transportation System (NextGen). A critical component of integrating UA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e416e3384b2404a29043ca0da8e22fc
https://doi.org/10.1109/sieds.2013.6549509

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Gamma delta T cells in the pathobiology of murine acute graft-versus-host disease. Evidence that gamma delta T cells mediate natural killer-like cytotoxicity in the host and that elimination of these cells from donors significantly reduces mortality

Autor: C A Ellison, G C MacDonald, E S Rector, J G Gartner

Publikováno v: The Journal of Immunology. 155:4189-4198

NK-like cytotoxicity in F1-hybrid mice with acute GVH disease is mediated by donor-derived CD3+/CD4-/CD8- cells that can lyse both NK-sensitive YAC-1 target cells as well as NK-resistant targets such as BW1100 and P815. Our objective was to determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41818b1197585c9d9e83bbfc0910cb96
https://doi.org/10.4049/jimmunol.155.9.4189

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In vivo depletion of Thy-1-positive cells originating from normal bone marrow abrogates the suppression of gld disease in normal-gld mixed bone marrow chimeras

Autor: G C MacDonald, V N Kakkanaiah, E S Sobel, P L Cohen, R A Eisenberg

Publikováno v: The Journal of Immunology. 154:444-449

Mice homozygous for gld develop an autoimmune syndrome characterized by hypergammaglobulinemia, massive accumulation of abnormal T cells and the production of autoantibodies. Previous studies in our laboratory have shown that reconstitution of lethal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1477538bfa829aceac6abcfb577dcbb0
https://doi.org/10.4049/jimmunol.154.1.444

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Differential control of autoantibodies and lymphoproliferation by Fas ligand expression on CD4+ and CD8+ T cells in vivo

Autor: M A, Maldonado, G C, MacDonald, V N, Kakkanaiah, K, Fecho, M, Dransfield, D, Sekiguchi, P L, Cohen, R A, Eisenberg

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(6)

We have previously shown that the gld autoimmune syndrome is suppressed in lethally irradiated gld mice reconstituted with a mixture of normal and gld bone marrow (BM). Furthermore, in vivo depletion of normal Thy-1+ cells restores lymphoproliferatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b32b69a3943c0a16e66ef639fb046ece
https://pubmed.ncbi.nlm.nih.gov/10477580

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Depletion of natural killer cells from the graft reduces interferon-gamma levels and lipopolysaccharide-induced tumor necrosis factor-alpha release in F1 hybrid mice with acute graft-versus-host disease

Autor: C A, Ellison, K T, HayGlass, J M, Fischer, E S, Rector, G C, MacDonald, J G, Gartner

Publikováno v: Transplantation. 66(3)

We wished to determine whether removal of NK1.1+ cells from the graft provides protection against acute graft-versus-host disease (GVHD) by obviating the Th1 immune response that underlies the development of this disease.Graft-versus-host (GVH) react

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c02e86ea0c75d7178bb5a71ae592c2a
https://pubmed.ncbi.nlm.nih.gov/9721794

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B cell genotype determines the fine specificity of autoantibody in lpr mice

Autor: V N, Kakkanaiah, E S, Sobel, G C, MacDonald, R L, Cheek, P L, Cohen, R A, Eisenberg

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6702dee35159466910334a3a9a506289
https://pubmed.ncbi.nlm.nih.gov/9218626

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Autor: C A, Ellison, G C, MacDonald, E S, Rector, J G, Gartner

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 155(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70d5bfdac4cb5ac5de28f4e1df02e5d0
https://pubmed.ncbi.nlm.nih.gov/7594574

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In vivo depletion of Thy-1-positive cells originating from normal bone marrow abrogates the suppression of gld disease in normal-gld mixed bone marrow chimeras

Autor: G C, MacDonald, V N, Kakkanaiah, E S, Sobel, P L, Cohen, R A, Eisenberg

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 154(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fb6d1a7edeba6c7c0a327b6ed6c9b721
https://pubmed.ncbi.nlm.nih.gov/7527820

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