Zobrazeno 1 - 10
of 60
pro vyhledávání: '"G. C. FORD"'
Publikováno v:
Diabetologia. 49:543-551
In non-diabetic people, insulin levels in the liver are two-fold higher than those in the systemic circulation. In contrast, patients with type 1 diabetes have similar hepatic and systemic insulin levels because insulin is administered peripherally.
Autor:
M. J. ADAMS, G. C. FORD, R. KOEKOEK, P. J. LENTZ, A. McPHERSON, M. G. ROSSMANN, I. E. SMILEY, R. W. SCHEVITZ, A. J. WONACOTI
Publikováno v:
Selected Papers of Michael G Rossmann with Commentaries ISBN: 9789814513340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe05fea54804e4e78b3fb986f00e3c30
https://doi.org/10.1142/9789814513357_0010
https://doi.org/10.1142/9789814513357_0010
Autor:
David P. Hornby, G. C. Ford
Publikováno v:
Current Opinion in Biotechnology. 9:354-358
Since the discovery that the DNA methyltransferase M. Hha I utilises a base flipping mechanism to expose its target cytosine during catalysis, this phenomenon has been observed in other nucleic acid modifying enzymes. The crystallographic analyses of
Autor:
G. C. Ford, Alisdair R Fernie, D. M. Lawson, Paul D. Hempstead, Pauline M. Harrison, S J Yewdall, Peter J. Artymiuk, David W. Rice
Publikováno v:
Journal of Molecular Biology. 268:424-448
Mammalian ferritins are 24-mers assembled from two types of polypeptide chain which provide the molecule with different functions. H(eavy) chains catalyse the first step in iron storage, the oxidation of iron(II). L(ight) chains promote the nucleatio
Publikováno v:
Analytical Biochemistry. 247:228-236
A determinant of the accuracy of protein synthesis measurement using stable isotope is the purity of the protein under study. An Immunoaffinity chromatographic technique to sequentially purify human plasma albumin, fibrinogen, and apolipoprotein B-10
Publikováno v:
Journal of Clinical Investigation. 95:2926-2937
To elucidate the mechanism of insulin's anticatabolic effect in humans, protein dynamics were evaluated in the whole-body, splanchnic, and leg tissues in six C-peptide-negative type I diabetic male patients in the insulin-deprived and insulin-treated
Autor:
Venkatachalem Sathish, A. Barnes, Michael A. Thompson, G. C. Ford, Christina M. Pabelick, Dan F. Smelter, Y. S. Prakash, Amard J. Abcejo, K. J. Grim
Publikováno v:
British journal of anaesthesia. 109(3)
Background The i.v. anaesthetic propofol produces bronchodilatation. Airway relaxation involves reduced intracellular Ca2+ ([Ca2+]i) in airway smooth muscle (ASM) and lipid rafts (caveolae), and constitutional caveolin proteins regulate [Ca2+]i. We p
Autor:
Amyra Treffry, J. C. Livingstone, John R. Guest, Peter J. Artymiuk, J. M. A. Smith, Pauline M. Harrison, D. M. Lawson, S J Yewdall, Simon C. Andrews, J. Hirzmann, G. C. Ford
Publikováno v:
ChemInform. 22
Publisher Summary This chapter compares the structures of the iron cores and protein coats of ferritins and the hemoferritins of bacteria, and the current state of knowledge concerning mineralization processes in these molecules is discussed in relat
Publikováno v:
Biology of Metals. 4:95-99
The nature of the amino acids whose codons border introns in ferritin genes is novel; the disposition of these intron boundaries within the three-dimensional structure of the 24-subunit molecule differs significantly from that of other proteins. Thes
Publikováno v:
British Journal of Surgery. 77:791-794
The counter-regulatory hormones, including glucagon, may be involved in the generation of postoperative negative nitrogen balance. We examined the influence of glucagon on whole body and forearm muscle protein kinetics, determined by L-[1–13C,15N]