Zobrazeno 1 - 10
of 49
pro vyhledávání: '"G. C. Gazzola"'
Autor:
Ovidio Bussolati, Massimiliano G. Bianchi, Valeria Dall'Asta, C. Maggini, Bianca Maria Rotoli, G. C. Gazzola, C. Marchesi
Publikováno v:
Amino Acids. 31:93-99
We report here that chlorpromazine, a first generation antipsychotic drug, inhibits anionic amino acid transport mediated by system X(-) (AG) (EAAT transporters) in cultured human fibroblasts. With 30 microM chlorpromazine, transport inhibition is de
Autor:
G. C. Gazzola, Rossana Visigalli, Roberto Sala, Ovidio Bussolati, Renata Franchi-Gazzola, Elena Bevilacqua, Valeria Dall'Asta, Francesca Gaccioli
Publikováno v:
Acta Physiologica. 187:273-283
Sodium-dependent neutral amino acid transporter-2 (SNAT2), the ubiquitous member of SLC38 family, accounts for the activity of transport system A for neutral amino acids in most mammalian tissues. As the transport process performed by SNAT2 is highly
Autor:
Bianca Maria Rotoli, Guido Orlandini, Ovidio Bussolati, Rita Gatti, G. C. Gazzola, Stefano Guizzardi, Jacopo Uggeri, Valeria Dall'Asta
Publikováno v:
ResearcherID
When grown on permeable supports, pancreatic duct adenocarcinoma CAPAN-1 cells establish very high values of transepithelial resistance (TER). The addition of ethanol produced a dose-related, reversible drop in the TER of these cells, ranging from 15
Autor:
Valeria Dall'Asta, Bianca Maria Rotoli, G. C. Gazzola, Guido Orlandini, Ovidio Bussolati, Rita Gatti
Publikováno v:
Cells Tissues Organs. 170:237-245
Many epithelial cells cultured on plastic ware form domes, fluid-filled localized raisings of the cell monolayer. Domes are due to active vectorial ion transport and their presence demonstrates the maintenance of a differentiated polarized phenotype
Autor:
G. Padoani, L. Torielli, Massimiliano G. Bianchi, G. C. Gazzola, Rita Gatti, Ovidio Bussolati
Publikováno v:
Neuroscience. 169(2)
Excitatory amino acid carrier 1 (EAAC1) belongs to the family of the Na(+)-dependent glutamate carriers. Although the association between defective EAAC1 function and neurologic disease has been repeatedly studied, EAAC1 regulation is not yet fully u
Publikováno v:
Journal of Biological Chemistry. 267:8330-8335
The influx of L-threonine through system ASC does not influence the membrane potential in cultured human fibroblasts although comparable fluxes of amino acids through another Na(+)-dependent agency, system A, effectively depolarize the cells. The mem
Publikováno v:
Journal of Biological Chemistry. 266:1591-1596
The energization of System A in cultured human fibroblasts has been studied by measuring the energy transfer from the electrochemical gradient of Na+ to the chemical gradient of the site A-specific substrate amino acid 2-methylaminoisobutyric acid. T
Publikováno v:
Neuroscience. 151(4)
The transport of excitatory amino acids (EAA) in CNS is performed by a family of high affinity, sodium dependent carriers. One of these transporters, excitatory amino acid carrier 1 (EAAC1), is known to be regulated by several mechanisms that modify
Autor:
Ovidio Bussolati, C. Bozzetti, Rita Gatti, Saverio Tardito, Massimiliano G. Bianchi, G. C. Gazzola, Bianca Maria Rotoli, Jacopo Uggeri, Renata Franchi-Gazzola
Publikováno v:
Cancer chemotherapy and pharmacology. 60(5)
To evaluate the activity of the antitumor enzyme L: -asparaginase (ASNase) on tumor cells of mesenchymal origin and the contribution of glutamine synthetase (GS) to the adaptation to the metabolic stress caused by the anti-tumor enzyme.We studied the
Publikováno v:
Methods in enzymology. 307