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Akademický článek

Altitude and management affect soil fertility, leaf nutrient status and Xanthomonas wilt prevalence in enset gardens

Autor: S. Shara, R. Swennen, J. Deckers, F. Weldesenbet, L. Vercammen, F. Eshetu, F. Woldeyes, G. Blomme, R. Merckx, K. Vancampenhout

Publikováno v: SOIL, Vol 7, Pp 1-14 (2021)

Enset (Ensete ventricosum) is a productive, drought-tolerant and multipurpose food security crop grown in the densely populated Ethiopian highlands. It is a so-called orphan crop, and its production suffers from a lack of information on proper soil f

Externí odkaz: https://doaj.org/article/c60cd9d481c5435a87fec0ce70f9e5da

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Assessment of agronomic practices in banana-coffee and banana-cacao systems in eastern Democratic Republic of Congo – an entry point for sustainable and diversified organic systems

Autor: G. Blomme, W. Ocimati, L. Vutseme, N. Safari Kitumaini, M. Kamira, J. Ntamwira

Publikováno v: Acta Horticulturae. :71-80

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f91b6c3df0c9fcdcfea3c09fabdb121
https://doi.org/10.17660/actahortic.2023.1367.8

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Can edible mushrooms boost soil health in banana organic systems?

Autor: W. Ocimati, E. Were, G. Ogwal, M. Dita, A.F. Tazuba, S.J. Zheng, G. Blomme

Publikováno v: Acta Horticulturae. :107-116

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53aebef73a9c2d4903d448905c54c6dd
https://doi.org/10.17660/actahortic.2023.1367.12

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Akademický článek

Identification of VEGF Signaling Inhibition-Induced Glomerular Injury in Rats through Site-Specific Urinary Biomarkers

Autor: Yi Yang, Kenneth Kowalkowski, Rita Ciurlionis, Wayne R. Buck, Keith B. Glaser, Daniel H. Albert, Eric A. G. Blomme

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 23, p 12629 (2021)

Cancer therapies targeting the vascular endothelial growth factor (VEGF) signaling pathway can lead to renal damage by disrupting the glomerular ultrafiltration apparatus. The objective of the current study was to identify sensitive biomarkers for VE

Externí odkaz: https://doaj.org/article/303ab7d571f24aa7899afe4e5febdaf2

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Akademický článek

Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies

Autor: Mohan S. Rao, Terry R. Van Vleet, Rita Ciurlionis, Wayne R. Buck, Scott W. Mittelstadt, Eric A. G. Blomme, Michael J. Liguori

Publikováno v: Frontiers in Genetics, Vol 9 (2019)

Gene expression profiling is a useful tool to predict and interrogate mechanisms of toxicity. RNA-Seq technology has emerged as an attractive alternative to traditional microarray platforms for conducting transcriptional profiling. The objective of t

Externí odkaz: https://doaj.org/article/8f54e5a06be041a38c8aef764788a34c

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Akademický článek

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Preclinical species gene expression database: Development and meta-analysis

Autor: Caitlin Krause, Kinga Suwada, Eric A. G. Blomme, Kenneth Kowalkowski, Michael J. Liguori, Prathap Kumar Mahalingaiah, Scott Mittelstadt, Richard Peterson, Lauren Rendino, Andy Vo, Terry R. Van Vleet

Publikováno v: Frontiers in Genetics. 13

The evaluation of toxicity in preclinical species is important for identifying potential safety liabilities of experimental medicines. Toxicology studies provide translational insight into potential adverse clinical findings, but data interpretation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bf19863a802a9021cf5c0ea7d55e0e1
https://doi.org/10.3389/fgene.2022.1078050

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Akademický článek

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Akademický článek

Global Transcriptomic Profiling Using Small Volumes of Whole Blood: A Cost-Effective Method for Translational Genomic Biomarker Identification in Small Animals

Autor: Yi Yang, Eric A. G. Blomme, Michael J. Liguori, Paul M. Jung, Amy C. Ditewig, Meagan M. Fricano

Publikováno v: International Journal of Molecular Sciences, Vol 12, Iss 4, Pp 2502-2517 (2011)

Blood is an ideal tissue for the identification of novel genomic biomarkers for toxicity or efficacy. However, using blood for transcriptomic profiling presents significant technical challenges due to the transcriptomic changes induced by ex vivo han

Externí odkaz: https://doaj.org/article/d636467d74a24f9a93fa4054f7c844da

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Akademický článek

Comparison of TNFα to Lipopolysaccharide as an Inflammagen to Characterize the Idiosyncratic Hepatotoxicity Potential of Drugs: Trovafloxacin as an Example

Autor: Jeffrey F. Waring, Patricia E. Ganey, Robert A. Roth, Eric A. G. Blomme, David M. Nelson, Amy C. Ditewig, Jane F. Maddox, James P. Luyendyk, Lois D. Lehman-McKeeman, Vasanthi M. Bhaskaran, Michael J. Liguori

Publikováno v: International Journal of Molecular Sciences, Vol 11, Iss 11, Pp 4697-4714 (2010)

Idiosyncratic drug reactions (IDRs) are poorly understood, unpredictable, and not detected in preclinical studies. Although the cause of these reactions is likely multi-factorial, one hypothesis is that an underlying inflammatory state lowers the tol

Externí odkaz: https://doaj.org/article/cd16481e4a9f4fe5ad6ba562b8b8db9a

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