Zobrazeno 1 - 10
of 27
pro vyhledávání: '"G. Blackinton"'
Publikováno v:
Cancer Research. 83:5930-5930
DNA sequencing technology provides the capability to tell the story of every cell in a heterogenous sample. ResolveDNA® generates uniform coverage of >95% of a single genome, enabling researchers to generate single-cell genomic data of unparalleled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f69a923129fdb0b1a0ec93c0c3849e10
https://doi.org/10.1158/1538-7445.am2023-5930
https://doi.org/10.1158/1538-7445.am2023-5930
Autor:
Jon S. Zawistowski, Isai Salas-Gonzalez, Tia A. Tate, Tatiana V. Morozova, Katherine Kennedy, Durga M. Arvapalli, Swetha D. Velivela, Jamie E. Remington, Josh Croteau, Kevin Taylor, Jeff G. Blackinton, Victor J. Weigman, Jeffrey R. Marks, Eun-Sil Shelley Hwang, Gary L. Harton, Jay A. West
Publikováno v:
Cancer Research. 83:5933-5933
The ResolveOME™ single-cell amplification solution unites whole-genome and full-length transcriptome information from the same cell, providing critical insight between these layers not possible when analyzed in isolation. We expand here upon the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb7d91a61bb75597bd216b55b3a9149
https://doi.org/10.1158/1538-7445.am2023-5933
https://doi.org/10.1158/1538-7445.am2023-5933
Autor:
Jon S. Zawistowski, Isai Salas-González, Tatiana V. Morozova, Jeff G. Blackinton, Tia Tate, Durga Arvapalli, Swetha Velivela, Gary L. Harton, Jeffrey R. Marks, E. Shelley Hwang, Victor J. Weigman, Jay A.A. West
Discovering genomic variation in the absence of information about transcriptional consequence of that variation or, conversely, a transcriptional signature without understanding underlying genomic contributions, hinders understanding of molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02b57120e0460e9c1b8272715c52b35
https://doi.org/10.1101/2022.04.29.489440
https://doi.org/10.1101/2022.04.29.489440
Autor:
Stephanie L Moon, Jeffrey G Blackinton, John R Anderson, Mary K Dozier, Benjamin J T Dodd, Jack D Keene, Carol J Wilusz, Shelton S Bradrick, Jeffrey Wilusz
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004708 (2015)
We demonstrate that both Hepatitis C virus (HCV) and Bovine Viral Diarrhea virus (BVDV) contain regions in their 5' UTRs that stall and repress the enzymatic activity of the cellular 5'-3' exoribonuclease XRN1, resulting in dramatic changes in the st
Externí odkaz:
https://doaj.org/article/ccc5df6b60bf40dabcbfb5732937f2a6
Autor:
Jack D. Keene, Jeff G. Blackinton
Publikováno v:
Nucleic Acids Research
Global mRNA abundance depends on the balance of synthesis and decay of a population of mRNAs. To account for this balance during activation of T cells, we used metabolic labeling to quantify the contributions of RNA transcription and decay over a 4 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d4f31995f42a728742383bd1ab6f43
https://doi.org/10.1093/nar/gkv1066
https://doi.org/10.1093/nar/gkv1066
Autor:
Stephanie A. Freel, Guido Ferrari, Joy Pickeral, Georgia D. Tomaras, Nathan Vandergrift, Alyse Frisbee, Tamika L. Payne, Jack D. Keene, Jeff G. Blackinton, Sheetal Sawant
Publikováno v:
Journal of Virology. 88:9514-9528
The ability of CD8 + T cells to effectively limit HIV-1 replication and block HIV-1 acquisition is determined by the capacity to rapidly respond to HIV-1 antigens. Understanding both the functional properties and regulation of an effective CD8 + resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5fdd49c59219c01b769c37de9e7480
https://doi.org/10.1128/jvi.00802-14
https://doi.org/10.1128/jvi.00802-14
Autor:
Thomas Willows, Olof Sydow, Marie Westerlund, Caroline Ran, Anna Håkansson, Andrea Carmine Belin, Jeff G. Blackinton, Anna Anvret, Hans Nissbrandt
Publikováno v:
The Open Neurology Journal
Mutations in the PARK7 gene, DJ-1, have been reported to cause early-onset and familial Parkinson’s disease (PD). The function of DJ-1 and how it contributes to the development of the disease is not clear today, but several studies report that DJ-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aeb882ac177ee50d14e10aced83487f
https://doi.org/10.2174/1874205x01105010008
https://doi.org/10.2174/1874205x01105010008
Autor:
Jeff G. Blackinton, Jack D. Keene
Publikováno v:
Seminars in celldevelopmental biology. 34
The cellular growth cycle is initiated and maintained by punctual, yet agile, regulatory events involving modifications of cell cycle proteins as well as coordinated gene expression to support cyclic checkpoint decisions. Recent evidence indicates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb98c40d9439070c59e9ae093d960b4
https://pubmed.ncbi.nlm.nih.gov/24882724
https://pubmed.ncbi.nlm.nih.gov/24882724
Autor:
A. Okada, H. Bradner, S. Matsuno, R. H. March, R. Mitiguy, John Clem, G. Blackinton, David M. Karl, Yasuo Ohashi, C. E. Roos, D. O'Connor, John G. Learned, Michael S. Webster, J. Babson, A. Roberts
Publikováno v:
Deep Sea Research Part A. Oceanographic Research Papers. 38:201-217
Measurements of bioluminescence have been made at depths of about 4500 m with (1) freely falling, (2) ship-suspended and (3) bottom anchored instruments. A comparison of these measurements shows that most of the light recorded by ship-suspended measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72015656ecf8faa1de2e7957d614da5b
https://doi.org/10.1016/0198-0149(91)90080-y
https://doi.org/10.1016/0198-0149(91)90080-y
Autor:
Alexandra Beilina, Lars Olson, Dagmar Galter, Jeff G. Blackinton, Mark R. Cookson, Anna Anvret
Publikováno v:
Brain research. 1184
Mutations in PINK1 (PTEN-induced putative kinase 1) are causal for early onset recessive parkinsonism in humans, characterized by damage to the nigrostriatal system. In situ hybridization studies in rodent brains have suggested a predominantly neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed8f6220e2dd8d0946126b165f74c50
https://pubmed.ncbi.nlm.nih.gov/17950257
https://pubmed.ncbi.nlm.nih.gov/17950257