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Publikováno v:
Pharmacology. 59(4)
The histamine H(3) receptor shows high degree of stereoselectivity for histamine analogues branched in the side chain. The hypothesis that gastroprotection by (R)-alpha-methylhistamine could be H(3) receptor-mediated was tested by comparing the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::732da50db2bde3c386e9bd383ce81b0f
https://pubmed.ncbi.nlm.nih.gov/10474079
https://pubmed.ncbi.nlm.nih.gov/10474079
Autor:
G, Coruzzi, G, Bertaccini
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.). 15(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1569e562e88fa03626012ae0797d265
https://pubmed.ncbi.nlm.nih.gov/10319368
https://pubmed.ncbi.nlm.nih.gov/10319368
Publikováno v:
General pharmacology. 31(4)
1. The histamine H2 receptor agonists, dimaprit, impromidine, amthamine, and several dimaprit- and impromidine-analogues were investigated for their spasmolytic activity on the guinea pig duodenum, precontracted with acetylcholine or KCl. 2. Almost a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d9308a2b2654eda626bcd84cb2395b6
https://pubmed.ncbi.nlm.nih.gov/9792230
https://pubmed.ncbi.nlm.nih.gov/9792230
Publikováno v:
Arzneimittel-Forschung. 47(7)
The effect of a new histamine H2-receptor antagonist derived from the lamtidine molecule and containing a nitric oxide (NO)-donor furoxan moiety (derivative 1) was studied for its gastric antisecretory activity and for a possible gastroprotective eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47af924a996a75e63142bba6966891bf
https://pubmed.ncbi.nlm.nih.gov/9272244
https://pubmed.ncbi.nlm.nih.gov/9272244
Publikováno v:
Digestive diseases and sciences. 42(5)
(R)-alpha-Methylhistamine, a selective agonist of histamine H3 receptors, prevents macroscopically visible gastric lesions by absolute ethanol in the rat. A further insight into its activity was the aim of our study. Rats were given saline or (R)-alp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0a6af9bbc1ebeb62d57e4d0e997ad3e
https://pubmed.ncbi.nlm.nih.gov/9149057
https://pubmed.ncbi.nlm.nih.gov/9149057
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
The hypothesis that prejunctional histamine H3 receptors and alpha-2 adrenoceptors interact with each other was assessed on the cholinergic transmission of the guinea pig duodenum. Specific agonists acting at histamine H3 receptors, alpha-2 adrenocep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7959c50686e243654b187e53ca074c8
https://pubmed.ncbi.nlm.nih.gov/9103522
https://pubmed.ncbi.nlm.nih.gov/9103522
Publikováno v:
The Italian journal of gastroenterology. 28(9)
The effect of the histamine H3 receptor agonist (R) alpha-methylhistamine on duodenal bicarbonate secretion was investigated in the anaesthetized rat. (R) alpha-methylhistamine (3-30 mumol/kg i.v.) caused a dose-dependent increase in alkaline secreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8558a457cf8b3bc3f931778fd3b82f31
https://pubmed.ncbi.nlm.nih.gov/9131398
https://pubmed.ncbi.nlm.nih.gov/9131398
Publikováno v:
The Italian journal of gastroenterology. 28(8)
Fedotozine was rested in colonic strips removed during surgery from patients suffering from different diseases of the colon; the effects were compared to those of morphine and of the selective opiate agonist U-69593. Fedotozine did not affect the spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c6c3f82332cb0a39c21443ab691a7db
https://pubmed.ncbi.nlm.nih.gov/9032586
https://pubmed.ncbi.nlm.nih.gov/9032586
Publikováno v:
Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma. 67(3-4)
The ability of (R)-alpha-methylhistamine, the selective agonist of histamine H3 receptors, to reduce ethanol-induced gastric damage was examined in the rat. (R)-alpha-methylhistamine (1-100 mg/kg intragastrically) caused a dose-related reduction in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2614365d1f66719666696ab4c35dd70c
https://pubmed.ncbi.nlm.nih.gov/10021692
https://pubmed.ncbi.nlm.nih.gov/10021692