Zobrazeno 1 - 10
of 1 188
pro vyhledávání: '"G. Bates"'
Publikováno v:
PeerJ, Vol 12, p e18388 (2024)
Locally sustained release antimicrobials such as silver nanoparticles (AgNPs) might prove useful in combating local infections. Their elution has been investigated in Phosphate Buffered Saline (PBS) including from poloxamer 407 (P407). No information
Externí odkaz:
https://doaj.org/article/65d45b66926143a4864a560cfb2e7e11
Autor:
Konstantin Sharafutdinov, Sebastian Johannes Fritsch, Mina Iravani, Pejman Farhadi Ghalati, Sina Saffaran, Declan G. Bates, Jonathan G. Hardman, Richard Polzin, Hannah Mayer, Gernot Marx, Johannes Bickenbach, Andreas Schuppert
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 611-620 (2024)
Goal: Machine learning (ML) technologies that leverage large-scale patient data are promising tools predicting disease evolution in individual patients. However, the limited generalizability of ML models developed on single-center datasets, and their
Externí odkaz:
https://doaj.org/article/44befcf235114feabf6f4ed4938e85a4
Autor:
Sonal Mistry, Anup Das, Sina Saffaran, Nadir Yehya, Timothy E. Scott, Marc Chikhani, John G. Laffey, Jonathan G. Hardman, Luigi Camporota, Declan G. Bates
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Airway pressure release ventilation (APRV) is widely available on mechanical ventilators and has been proposed as an early intervention to prevent lung injury or as a rescue therapy in the management of refractory hypoxemia. Drivi
Externí odkaz:
https://doaj.org/article/9e0a79736aab4245a04b09c4885e6681
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The circadian system—an organism’s built-in biological clock—is responsible for orchestrating biological processes to adapt to diurnal and seasonal variations. Perturbations to the circadian system (e.g., pathogen attack, sudden enviro
Externí odkaz:
https://doaj.org/article/2d6fadffdaf34782985f8add9dac3cc8
Autor:
Chadi S. Barakat, Konstantin Sharafutdinov, Josefine Busch, Sina Saffaran, Declan G. Bates, Jonathan G. Hardman, Andreas Schuppert, Sigurður Brynjólfsson, Sebastian Fritsch, Morris Riedel
Publikováno v:
Diagnostics, Vol 13, Iss 12, p 2098 (2023)
Acute Respiratory Distress Syndrome (ARDS) is a condition that endangers the lives of many Intensive Care Unit patients through gradual reduction of lung function. Due to its heterogeneity, this condition has been difficult to diagnose and treat, alt
Externí odkaz:
https://doaj.org/article/68f993e2e5b9465ea5347f526a18c844
Autor:
Liam Weaver, Anup Das, Sina Saffaran, Nadir Yehya, Timothy E. Scott, Marc Chikhani, John G. Laffey, Jonathan G. Hardman, Luigi Camporota, Declan G. Bates
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Background There is on-going controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure.
Externí odkaz:
https://doaj.org/article/f000987f12f844c988b045c84903b823
Autor:
Ahmad A. Mannan, Declan G. Bates
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
A promising strategy to increase product synthesis from bacteria uses inducible systems to switch metabolism to production. Here, the authors use models to show how engineering positive feedback loops into the genetic circuitry creates a switch that
Externí odkaz:
https://doaj.org/article/925f3bab049a46a39d8569145e04adbe
Publikováno v:
Bioengineering, Vol 10, Iss 4, p 466 (2023)
Chemical reaction networks can be utilised as basic components for nucleic acid feedback control systems’ design for Synthetic Biology application. DNA hybridisation and programmed strand-displacement reactions are effective primitives for implemen
Externí odkaz:
https://doaj.org/article/7df6b497327242258ad7ae2f9f92ca3c
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract Background Primary blast lung injury (PBLI) presents as a syndrome of respiratory distress and haemoptysis resulting from explosive shock wave exposure and is a frequent cause of mortality and morbidity in both military conflicts and terrori
Externí odkaz:
https://doaj.org/article/59145359e02f4deb94eba30f8720c92b
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Recent analyses of patient data in acute respiratory distress syndrome (ARDS) showed that a lower ventilator driving pressure was associated with reduced relative risk of mortality. These findings await full validation in prospect
Externí odkaz:
https://doaj.org/article/e88d2ee66e6f49a19f35a3bfe1fdf373