Zobrazeno 1 - 10 of 20 pro vyhledávání: '"G. B. Kohlhaw"'
1
Yeast transcriptional regulator Leu3p. Self-masking, specificity of masking, and evidence for regulation by the intracellular level of Leu3p
Autor: D, Wang, F, Zheng, S, Holmberg, G B, Kohlhaw
Publikováno v: The Journal of biological chemistry. 274(27)
Recent work suggests that the masking of the activation domain (AD) of yeast transactivator Leu3p, observed in the absence of the metabolic signal alpha-isopropylmalate, is an intramolecular event. Much of the evidence came from the construction and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0cb5ac24866f9e97fc14a5929e18c12e
https://pubmed.ncbi.nlm.nih.gov/10383402
Zobrazit plný text záznamu
2
Purification and structural characterization of transcriptional regulator Leu3 of yeast
Autor: J Y, Sze, G B, Kohlhaw
Publikováno v: The Journal of biological chemistry. 268(4)
The transcriptional regulatory protein Leu3 of Saccharomyces cerevisiae was enriched approximately 70-fold above wild type level in yeast cells carrying a pGAL1-LEU3 expression vector. Sustained overproduction of Leu3 following induction by galactose
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f73d582c010ad22d7648da7c2d7368d0
https://pubmed.ncbi.nlm.nih.gov/8428928
Zobrazit plný text záznamu
3
Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans
Autor: K M, Zhou, G B, Kohlhaw
Publikováno v: The Journal of biological chemistry. 265(29)
The LEU3 protein of yeast activates a number of genes in the branched chained amino acid pathways. Native LEU3 is modulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis. alpha-Isopropylmalate is needed for transcriptional activat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b056d66ecb2d2ff3a03865152a21a8e4
https://pubmed.ncbi.nlm.nih.gov/2211632
Zobrazit plný text záznamu
4
Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2
Autor: P R, Brisco, G B, Kohlhaw
Publikováno v: The Journal of biological chemistry. 265(20)
We have constructed a total deletion of the regulatory gene LEU3. Comparing the deletion mutant with a leu3 spontaneous mutant, we find that both types of mutants have lost the ability to regulate a LEU2'-lacZ translational fusion by the LEU3-alpha-i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26fe6637ed9326cc51db95e0e2c66a39
https://pubmed.ncbi.nlm.nih.gov/2195025
Zobrazit plný text záznamu
6
Inactivation of yeast alpha-isopropylmalate synthase by CoA. Antagonism between CoA and adenylates and the mechanism of CoA inactivation
Autor: G B Kohlhaw, D M Hampsey
Publikováno v: Journal of Biological Chemistry. 256:3791-3796
Yeast alpha-isopropylmalate synthase (EC 4.1.3.12) is inactivated by micromolar concentrations of CoA in the presence of Zn2+. We report here that rapid reactivation of inactivated enzyme (full recovery in less than 10 min) occurred in the presence o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fb5e676616a1ddc9b9460f3814e8e04
https://doi.org/10.1016/s0021-9258(19)69524-4
Zobrazit plný text záznamu
7
Structure of yeast LEU4. The 5' flanking region contains features that predict two modes of control and two productive translation starts
Autor: L.-F. L. Chang, G. B. Kohlhaw, A. R. Hinkkanen, J. P. Beltzer
Publikováno v: Journal of Biological Chemistry. 261:5160-5167
The nucleotide sequence of LEU4, a yeast gene encoding alpha-isopropylmalate synthase, has been determined. An open reading frame of 1857 nucleotides specifies a protein of 619 residues whose calculated molecular weight (68,416) and amino acid compos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e0b0e1539cd603d2c4a69d05dbafd00
https://doi.org/10.1016/s0021-9258(19)89228-1
Zobrazit plný text záznamu
10
Structure of yeast LEU4. The 5' flanking region contains features that predict two modes of control and two productive translation starts
Autor: J P, Beltzer, L F, Chang, A E, Hinkkanen, G B, Kohlhaw
Publikováno v: The Journal of biological chemistry. 261(11)
The nucleotide sequence of LEU4, a yeast gene encoding alpha-isopropylmalate synthase, has been determined. An open reading frame of 1857 nucleotides specifies a protein of 619 residues whose calculated molecular weight (68,416) and amino acid compos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c88711b0695f2de325049a0827961c8
https://pubmed.ncbi.nlm.nih.gov/2420798
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje