Zobrazeno 1 - 10 of 100 pro vyhledávání: '"G. Arts"'
1
Akademický článek
Intercellular adhesion molecule 2 regulates diapedesis hotspots by allowing neutrophil crawling against the direction of flow
Autor: Max L B Grönloh, Merel E Tebbens, Marianthi Kotsi, Janine J G Arts, Jaap D van Buul
Publikováno v: Vascular Biology, Vol 5, Iss 1, Pp 1-13 (2023)
Intercellular adhesion molecules (ICAMs) are cell surface proteins that play a crucial role in the body’s immune response and inflammatory processes. ICAM1 and ICAM2 are two ICAM family members expressed on the surface of various cell types, includ
Externí odkaz: https://doaj.org/article/4f15ddf2758745e1b658499b089f0162
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2
Akademický článek
A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium
Autor: Franka H. van der Linden, Eike K. Mahlandt, Janine J. G. Arts, Joep Beumer, Jens Puschhof, Saskia M. A. de Man, Anna O. Chertkova, Bas Ponsioen, Hans Clevers, Jaap D. van Buul, Marten Postma, Theodorus W. J. Gadella, Joachim Goedhart
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Currently, genetically encoded calcium indicators are not suitable for direct quantification. Here the authors engineer a fluorescence lifetime imaging calcium biosensor, Turquoise Calcium Fluorescence LIfeTime Sensor (Tq-Ca-FLITS), and measure intra
Externí odkaz: https://doaj.org/article/28e02e090b82435fa3bc07ed281bc827
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3
Akademický článek
Endothelial Focal Adhesions Are Functional Obstacles for Leukocytes During Basolateral Crawling
Autor: Janine J. G. Arts, Eike K. Mahlandt, Lilian Schimmel, Max L. B. Grönloh, Sanne van der Niet, Bart J. A. M. Klein, Mar Fernandez-Borja, Daphne van Geemen, Stephan Huveneers, Jos van Rijssel, Joachim Goedhart, Jaap D. van Buul
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
An inflammatory response requires leukocytes to migrate from the circulation across the vascular lining into the tissue to clear the invading pathogen. Whereas a lot of attention is focused on how leukocytes make their way through the endothelial mon
Externí odkaz: https://doaj.org/article/c305759e1af542afa349976b10539ac8
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4
Akademický článek
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6
Opto-RhoGEFs: an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength
Autor: Eike K. Mahlandt, Sebastián Palacios Martínez, Janine J. G. Arts, Simon Tol, Jaap D. van Buul, Joachim Goedhart
The inner layer of blood vessels consists of endothelial cells, which form the physical barrier between blood and tissue. This vascular barrier is tightly regulated to allow the passage of essential molecules like oxygen, carbon-dioxide, water, ions,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daa703b53329f0defe16f2c5f4ff69f
https://doi.org/10.7554/elife.84364.1
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7
Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM-1
Autor: Max L B Grönloh, Janine J G Arts, Sebastián Palacios Martínez, Amerens A van der Veen, Lanette Kempers, Abraham C I van Steen, Joris J T H Roelofs, Martijn A Nolte, Joachim Goedhart, Jaap D van Buul
Publikováno v: Grönloh, M L B, Arts, J J G, Palacios Martínez, S, van der Veen, A A, Kempers, L, van Steen, A C I, Roelofs, J J T H, Nolte, M A, Goedhart, J & van Buul, J D 2023, ' Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM-1 ', EMBO Reports, vol. 24, no. 1, e55483 . https://doi.org/10.15252/embr.202255483
EMBO reports, 24(1):e55483. Wiley-Blackwell
EMBO Reports, 24(1):e55483. Wiley-Blackwell
Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration ‘hotspot’ regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that endot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668e948a7eee2654f8daa2c0cb6818aa
https://research.vumc.nl/en/publications/977802a3-56bf-40d5-8031-092edf437de6
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8
Health-related quality of life after interval cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with stage III ovarian cancer
Autor: J. H. Schagen van Leeuwen, Simone N. Koole, M A P C van Ham, Arend G. J. Aalbers, Ralph H. Hermans, W.J. van Driel, Gabe S. Sonke, I.H.J.T. de Hingh, Victor J. Verwaal, Karolina Sikorska, J. van der Velden, Henk W.R. Schreuder, Jacobien M. Kieffer, Neil K. Aaronson, K.K. Van de Vijver, Henriette J. G. Arts
Publikováno v: European Journal of Surgical Oncology, 47, 101-107
European Journal of Surgical Oncology, 47, 1, pp. 101-107
Koole, S N, Kieffer, J M, K.Sikorska, Schagen van Leeuwen, J H, Schreuder, H W R, Hermans, R H, de Hingh, I H, van der Velden, J, Arts, H J, van Ham, M A P C, Aalbers, A G, Verwaal, V J, Van de Vijver, K K, Sonke, G S, van Driel, W J & Aaronson, N K 2021, ' Health-related quality of life after interval cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with stage III ovarian cancer ', European Journal of Surgical Oncology, vol. 47, no. 1, pp. 101-107 . https://doi.org/10.1016/j.ejso.2019.05.006
Introduction The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery (CRS) improves recurrence-free (RFS) and overall survival (OS) in patients with FIGO stage III ovarian cancer. We evaluated the effect of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a663b5dfcc3947bddfc209fc18114c8b
https://hdl.handle.net/11370/87f6cf02-6a98-4685-989e-d4ce2a3aa0a5
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9
A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium
Autor: Joachim Goedhart, Jens Puschhof, de Man Sm, Janine J. G. Arts, Anna O. Chertkova, Eike K. Mahlandt, Marten Postma, van Buul Jd, van der Linden Fh, Bas Ponsioen, T. W. J. Gadella, Joep Beumer, Hans Clevers
Publikováno v: Nature Communications, 12(1). Nature Publishing Group
Nature communications, 12(1):7159. Nature Publishing Group
Nature Communications
Nature Communications, 12:7159. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The most successful genetically encoded calcium indicators (GECIs) employ an intensity or ratiometric readout. Despite a large calcium-dependent change in fluorescence intensity, the quantification of calcium concentrations with GECIs is problematic,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c7ed39a6bb289f2724218075b9172a
https://pure.knaw.nl/portal/en/publications/3acdad4d-db2c-417e-a263-744ab40a2353
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10
Akademický článek
Folate Receptor-Beta Has Limited Value for Fluorescent Imaging in Ovarian, Breast and Colorectal Cancer.
Autor: Esther de Boer, Lucia M A Crane, Marleen van Oosten, Bert van der Vegt, Tineke van der Sluis, Paulien Kooijman, Philip S Low, Ate G J van der Zee, Henriette J G Arts, Gooitzen M van Dam, Joost Bart
Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135012 (2015)
Tumor-specific targeted imaging is rapidly evolving in cancer diagnosis. The folate receptor alpha (FR-α) has already been identified as a suitable target for cancer therapy and imaging. FR-α is present on ~40% of human cancers. FR-β is known to b
Externí odkaz: https://doaj.org/article/8ee93fb047004a198179bddc54e38405
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