Ultra‐low depth sequencing of plasma cell DNA for the detection of copy number aberrations in multiple myeloma

Autor: Michel Delforge, Peter Vandenberghe, Nancy Boeckx, Barbara Dewaele, Thomas Tousseyn, Jia Ding, G Ameye, Joris Vermeesch, Lucienne Michaux, Stefan Lehnert, Sanne Smits, Lieselot Buedts

Publikováno v: Genes, Chromosomes and Cancer. 59:465-471

Cytogenetic abnormalities are powerful prognostic factors in multiple myeloma (MM) and are routinely analyzed by FISH on bone marrow (BM) plasma cells (PC). Although considered the gold standard, FISH experiments can be laborious and expensive. There

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f6edae8482197e7c486a4f2d981604
https://doi.org/10.1002/gcc.22848

The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11

Autor: Virginie Eclache, John Boudjarane, Naïs Prade, Stéphanie Struski, Laetitia Largeaud, Cyril Broccardo, Joop H. Jansen, Christine Terré, Marie-Agnès Collonge-Rame, Pierre-Yves Juvin, Dominique Penther, Stéphanie Lagarde, Antoine Ittel, Véronique Mansat-De Mas, G Ameye, Isabelle Luquet, Marina Lafage-Pochitaloff, Carole Barin, David Rombaut, Bastien Gerby, Carine Gervais, Steven Richebourg, Oliver M. Dovey, Pierre Bories, Christine Lefebvre, Isabelle Radford-Weiss, Audrey Bidet, Isabelle Tigaud, George S. Vassiliou, Benedicte Ribourtout, Tobias Tekath, Michaela Fontenay, Lucienne Michaux, Sylvie Hébrard, Hélène Antoine-Poirel, Laura Jamrog, Vincent Fregona, Nathalie Nadal, Eric Delabesse, Véronique Baccini, Kosuke Yusa

Publikováno v: Blood Advances, 6, 2, pp. 386-398
Blood Advances
Blood Advances, 6, 386-398
Blood Advances, The American Society of Hematology, 2021, ⟨10.1182/bloodadvances.2021005311⟩

Key Points We detail at clinical, cytological, cytogenetic, and molecular levels 113 cases of MDS and MDS/MPN with del(11q), a rare recurrent event.CADM1, a tumor suppressor gene identified initially in solid tumors, ATM, CBL, and KMT2A are deleted a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a801474f49c15e8392848015e288927
https://repository.ubn.ru.nl/handle/2066/244555

Aneurysmal bone cystic lesions: value of genomic studies

Autor: C, Galant, P-L, Docquier, G, Ameye, Y, Guiot, J, Malghem, H A, Poirel

Publikováno v: Acta orthopaedica Belgica. 82(4)

Aneurysmal bone cystic (ABC) lesions can be primary or secondary (to a trauma or a pre-existing benign or malignant tumour). Specific translocations of the USP6 gene are reported in about 70% of primary but never in secondary ABC lesions. We report t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f59a68bd33676ce60735a93d17e189eb
https://pubmed.ncbi.nlm.nih.gov/29182118

The value of interphase fluorescence in situ hybridization for the detection of translocation t(12;21) in childhood acute lymphoblastic leukemia

Autor: Jeanne-Marie Libouton, Guy Cornu, Christine Verellen-Dumoulin, Véronique Deneys, C Bilhou-Nabera, Caroline Jacquy, Michel Stul, Lucienne Michaux, A. Zenebergh, Anne Hagemeijer, Philippe Martiat, Jean-Luc Vaerman, G Ameye

Publikováno v: Annals of Hematology. 79:259-268

Translocation t(12;21)(p13;q22) is the most frequent cytogenetic abnormality in childhood acute lymphoblastic leukemia (ALL) and is generally associated with favorable prognosis. In this report, we assessed the value of dual-color interphase fluoresc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7a2ba9c21b39414a62b3169b605c8d
https://doi.org/10.1007/s002770050590

Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence

Autor: Laurent G, Ameye, Winnie S S, Chee

Publikováno v: Arthritis Research & Therapy

The scientific and medical community remains skeptical regarding the efficacy of nutrition for osteoarthritis despite their broad acceptation by patients. In this context, this paper systematically reviews human clinical trials evaluating the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f436633f40e23735cd746d05d59ab5cf
https://pubmed.ncbi.nlm.nih.gov/16859534