Zobrazeno 1 - 10
of 76
pro vyhledávání: '"G. A. Ordway"'
Publikováno v:
Scandinavian Journal of Medicine & Science in Sports. 1:130-133
We tested the hypothesis that the biochemical properties of cardiac beta-adrenergic receptors (βAR), as determined by standard in vitro methods, limit physiological responsiveness of dogs to PAR stimulation during peak exercise. Accordingly, we meas
Autor:
Keith C. DeRuisseau, G. A. Ordway, Darin J. Falk, Tossaporn Yimlamai, Andreas N. Kavazis, Scott K. Powers, Melissa A. Deering, Darin Van Gammeren
Publikováno v:
Journal of Applied Physiology. 98:1314-1321
Prolonged mechanical ventilation (MV) results in diaphragmatic atrophy due, in part, to an increase in proteolysis. These experiments tested the hypothesis that MV-induced diaphragmatic proteolysis is accompanied by increased expression of key compon
Publikováno v:
Critical Care Medicine. 32:1338-1345
OBJECTIVE This study was designed to determine whether cutaneous burn injury up-regulated expression of myocardial heat shock protein (HSP)70 and to determine a potential cardioprotective role of inducible HSP70 (iHSP70) in postburn myocardial contra
Autor:
G. A. Ordway, Joseph J. Wakshlag, Daryl V. Nydam, Gary Mitchell Davenport, Bruce W. Christensen, Stephen C. Barr, F A Kallfelz, L. A. Shepard, C. E. Flaherty
Publikováno v:
Journal of Animal Physiology and Animal Nutrition. 87:408-420
To determine the effect of dietary protein intake on lean body wasting in adult canines a study was undertaken to investigate the Ubiquitin Proteasome (UP) pathway and concurrent changes in lean and fat body mass of canines fed variable sources and c
Publikováno v:
Acta Physiologica Scandinavica. 168:623-634
Myoglobin (Mb) is a large protein that reversibly binds oxygen in the muscle cell and is thought to be critical for O2 supply to the mitochondria during exercise. The role of Mb in aerobic function is evaluated based on the physical properties of Mb
Publikováno v:
Journal of Applied Physiology. 88:1134-1141
Remodeling of skeletal muscle in response to altered patterns of contractile activity is achieved, in part, by the regulated degradation of cellular proteins. The ubiquitin-proteasome system is a dominant pathway for protein degradation in eukaryotic
Autor:
Eva R. Chin, Rhonda Bassel-Duby, Robert W. Grange, R. Sanders Williams, Nina B. Radford, Daniel J. Garry, G. A. Ordway, John N. Lorenz
Publikováno v:
Nature. 395:905-908
Myoglobin, an intracellular haemoprotein expressed in the heart and oxidative skeletal myofibres of vertebrates, binds molecular oxygen and may facilitate oxygen transport from erythrocytes to mitochondria, thereby maintaining cellular respiration du
Publikováno v:
American Journal of Physiology-Cell Physiology. 274:C341-C346
Endurance exercise training increases the oxidative capacity of skeletal muscles, reflecting the induction of genes encoding enzymes of intermediary metabolism. To test the hypothesis that changes in gene expression may be triggered specifically duri
Publikováno v:
Journal of Clinical Investigation. 94:277-285
Sustained contractile activity of skeletal muscle promotes angiogenesis, as well as transformation of contractile protein isoforms and mitochondrial proliferation within myofibers. Since the products of immediate early genes such as c-fos, c-jun, and
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C1511-C1516
A small RNA encoded within the nucleus of yeast and mammalian cells is an essential subunit of a mitochondrial RNA-processing endonuclease (RNase MRP) that generates primers for mitochondrial DNA (mtDNA) replication. We examined expression of MRP-RNA