Zobrazeno 1 - 10
of 19
pro vyhledávání: '"G. A. Leeson"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(6)
Terfenadine (Seldane) undergoes extensive metabolism to form azacyclonol and terfenadine alcohol. Terfenadine alcohol is subsequently metabolized to azacyclonol and terfenadine acid. Although testosterone 6 beta-hydroxylation [CYP3A(4)] has been show
Autor:
G. W. Leeson
Publikováno v:
The Police Journal: Theory, Practice and Principles. 53:43-51
The following is a revised, non-technical version of a paper produced by the author at the Demography Department of the University's Statistic Institute, entitled ‘A Multiple Incre-Decrement Model for a Hierarchically Graded Manpower System’. In
Publikováno v:
Toxicological Sciences. 4:261-269
Cilobamine , an antidepressant, was investigated for its influence on the hepatic drug metabolizing enzymes ( DME ) of male Charles River CD rats. Cilobamine doses (3, 10, 30, 100, and 300 mg/kg po, as free base) were compared to sodium phenobarbital
Autor:
G. W. Leeson
Publikováno v:
OR Spektrum. 4:35-40
Autor:
G. W. Leeson
Publikováno v:
Operations-Research-Spektrum. 5:219-222
An important aspect of manpower planning in hierarchical systems is knowledge of the limiting structure given a continuation of observed wastage and promotion experience. In this paper, a system with employees classified according to grade and comple
Autor:
G. E. Leeson
Publikováno v:
Bulletin of the School of Oriental and African Studies. 4:331-335
Bābū Śyām Sundae Dās, President of the Nāgarī Pracārinī Sabhā, has recently written a book entitled Bhāsā Vigyān (Benares, Sāhitya-Ratn-Mālā, 1920, pp. 6 + v + 388 + xxii). In this work he has collected a large amount of material for
Autor:
C. Hampton, D.J. Sprinkle, John P. Gibson, K.W. Huffman, G.J. Wright, David E. Loudy, G. A. Leeson, John T. Yarrington
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 3(2)
The ferrocene hematinic MDL 80,478 was administered orally at dosages ranging from 0 to 500 mg/kg/day to dogs (2 weeks), monkeys (6 weeks), and rats (6 weeks). Rats given 500 mg/kg/day had distended abdomens due to enlarged livers while the high-dose
Publikováno v:
Arzneimittel-Forschung. 32(9a)
Alpha-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1- piperidinebutanol (terfenadine, RMI 9918, Triludan, Teldane, resp.), a clinically effective antihistamine, with little or no central nervous system effects, was investigated in order to
Autor:
G W, Leeson
Publikováno v:
Ugeskrift for laeger. 143(36)
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 4(3)
Tilorone hydrochloride, 2,7-bias(2-(diethylamino)ethoxy(fluoren-9-one dihydrochloride, has been studied to determine its effect on the drug-metabolizing enzymes of the liver of male Charles River CD strain rats. Single and multiple doses of tilorone-