Zobrazeno 1 - 10 of 14 pro vyhledávání: '"G. A. Heavner"'
1
Peptides Derived from the Lectin Domain of Selectin Adhesion Molecules Inhibit Leukocyte Rolling In Vivo
Autor: Eric J. Kunkel, C. Scheding, Keith E. Norman, Klaus Ley, G. A. Heavner
Publikováno v: Microcirculation. 3:29-38
The selectins are a family of adhesion molecules that mediate leukocyte rolling, a prerequisite for their later firm adhesion and migration to sites of inflammation. The N-terminal lectin domain of selectins is important for Ca(2+)-dependent binding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6104a8a568abe569e426ac054227d4
https://doi.org/10.3109/10739689609146780
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3
A Synthetic Peptide Approach for Elucidating the Points of Natural Auto-Antibody Reactivity to Proteolytic Fragments of Human IgG
Autor: B. Whitaker, Marian Kruszynski, R. E. Jordan, D. De Riggi, A. Schmidt, G. A. Heavner
Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9780387736563
Introduction There are naturally occurring human antibodies to the F(ab’)2 portion of IgG [1]. Extracellular proteases and bacterial enzymes can cleave the IgG hinge region and release the Fc domain (with its effector functions. The human immune re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fc4ba6bb3ab8258d92e7850c0281ecc
https://doi.org/10.1007/978-0-387-73657-0_177
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5
Lectin domain peptides from selectins interact with both cell surface ligands and Ca2+ ions
Autor: J G, Geng, G A, Heavner, R P, McEver
Publikováno v: The Journal of biological chemistry. 267(28)
Selectins are receptors that mediate leukocyte adhesion to platelets or endothelial cells through Ca(2+)-dependent interactions with cell surface oligosaccharides. We found that peptides corresponding to residues 23-30, 54-63, and 70-79 of the N-term
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e781cd68b9dcc3c78545621671acaab
https://pubmed.ncbi.nlm.nih.gov/1383198
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6
Pharmacokinetics and Pharmacodynamics of CNTO 528, a Novel Erythropoietin Receptor Agonist in Normal and Anemic Rats
Autor: Ian E. James, Bernard Scallon, E. Eirikis, Paul W. Fisher, K. Shamberger, G. A. Heavner, Peter Bugelski, Chichi Huang, T. Spinka-Doms, J. Ghrayeb, C. Pool, Dorie Makropoulos, H. Jang, Thomas Nesspor, Josie Fisher, D. B. Knight, Amy L. Volk, B. Miller
Publikováno v: Blood. 106:4261-4261
CNTO 528 is a member of a group of novel stimulants of erythropoiesis that has recently entered clinical trials. Although CNTO 528 bears no sequence homology to erythropoietin (EPO), it is an EPO receptor agonist, capable of rescuing EPO-dependent ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c23f38df5a9f3eca3e10b74c1216706
https://doi.org/10.1182/blood.v106.11.4261.4261
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8
Developmental and behavioral effects of early postnatal exposure to triethyltin in rats
Autor: L W, Reiter, G B, Heavner, K F, Dean, P H, Ruppert
Publikováno v: Neurobehavioral toxicology and teratology. 3(3)
On Day 5 of postnatal life, rat pups received a single injection of triethyltin and were later tested for a variety of developmental and adult behaviors. A within-litter dosing design was used with one male and one female from each litter (N = 8 pups
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bacb21c07a3d01ededd0987f9b296f01
https://pubmed.ncbi.nlm.nih.gov/7290284
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