Výsledky vyhledávání - "G. A. C. Brito"

The Alpha-Lipoic Acid Improves Survival and Prevents Irinotecan-Induced Inflammation and Intestinal Dysmotility in Mice

Autor: Pedro Marcos Gomes Soares, Silvânia Maria Mendes Vasconcelos, Emmanuel P. Souza, G. A. C. Brito, Ana Luiza Viana Pequeno, Conceição da Silva Martins, Daniely Viana da Silva Costa, Ingridy da Silva Medeiros, Dainesy Santos Martins, Angeline M. H. P. Silva, Roberto C. P. Lima-Júnior, Caren Nádia Soares de Sousa, Deiziane Viana da Silva Costa

Publikováno v: Pharmaceuticals, Vol 13, Iss 361, p 361 (2020)
Pharmaceuticals
Volume 13
Issue 11
Repositório Institucional da Universidade Federal do Ceará (UFC)
Universidade Federal do Ceará (UFC)
instacron:UFC

Irinotecan, an anticancer drug, induces diarrhea and intestinal inflammation, resulting in an increase in the cost of care and in treatment delays. In this study, we investigated whether alpha-lipoic acid (&alpha
LA) could improve irinotecan-med

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9652455f7e5fe78d34c8cda6deb34b1
https://www.mdpi.com/1424-8247/13/11/361

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Interleukin-4 Modulates the Inflammatory Response in Ifosfamide-Induced Hemorrhagic Cystitis

Autor: Reinaldo B. Oriá, Helano C. Freitas, Lívia T. C. Mourão, Fernando Q. Cunha, Roberto C. P. Lima-Júnior, Mariana Lima Vale, G. A. C. Brito, Deysi Viviana Tenazoa Wong, Francisco Yuri Bulcão Macedo, Ronaldo A. Ribeiro

Publikováno v: Inflammation. 35:297-307

We investigated whether interleukin-4 (IL-4) is present and capable of reducing inflammatory changes seen in ifosfamide-induced hemorrhagic cystitis. Male Swiss mice were treated with saline or ifosfamide alone or ifosfamide with the classical protoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118a7a33b1c5bd4f99016d6ea14dfd54
https://doi.org/10.1007/s10753-011-9319-3

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Protective effect of α- and β-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice

Autor: G. A. C. Brito, Fernanda R.C. Almeida, Mariana Helena Chaves, Regilane M. Silva, Francisco Artur Forte Oliveira, Flávia A. Santos, Roberto C.P. Lima, Vietla Satyanarayana Rao, Juliana L. Maia

Publikováno v: Journal of Ethnopharmacology. 98:103-108

In the search of hepatoprotective agents from natural sources, alpha- and beta-amyrin, a triterpene mixture isolated from the trunk wood resin of folk medicinal plant, Protium heptaphyllum was tested against acetaminophen-induced liver injury in mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08040c920a1968a4259dc6883c4b45a8
https://doi.org/10.1016/j.jep.2005.01.036

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Use of dexamethasone with mesna for the prevention of ifosfamide-induced hemorrhagic cystitis

Autor: Milena Morais Vieira, Ronaldo A. Ribeiro, Erik Aquino Nery, Fernando Q. Cunha, G. A. C. Brito, Francisco Yuri Bulcão Macedo, José Nelson Belarmino-Filho

Publikováno v: International Journal of Urology. 10:595-602

Aim: Hemorrhagic cystitis (HC) is a limiting side-effect of chemotherapy with ifosfamide (IFS). In the study presented here, we investigated the use of dexamethasone in combination with mesna for the prevention of IFS-induced HC. Methods: Male Wistar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9e6d41524646a2f1a1494d89408204
https://doi.org/10.1046/j.1442-2042.2003.00709.x

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Tumor necrosis factor-alpha and interleukin-1beta mediate the production of nitric oxide involved in the pathogenesis of ifosfamide induced hemorrhagic cystitis in mice

Autor: R A, Ribeiro, H C, Freitas, M C, Campos, C C, Santos, F C, Figueiredo, G A C, Brito, F Q, Cunha

Publikováno v: The Journal of urology. 167(5)

We investigated the participation of nitric oxide in ifosfamide induced hemorrhagic cystitis in mice, and the involvement of tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta in the induction of nitric oxide production in this model.Hemorr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae9f2fb9621d16980fd13b2bc87d64e0
https://pubmed.ncbi.nlm.nih.gov/11956484

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Effects of pentoxifylline and nabumetone on the serum levels of IL-1beta and TNFalpha in rats with adjuvant arthritis

Autor: Marcos Fábio Gadelha Rocha, D. B. de Menezes, A.A.M. Lima, G. A. C. Brito, J. C. R. Silva, Vietla Satyanarayana Rao

Publikováno v: Scopus-Elsevier

Objective and Design: This study examined whether serum levels of cytokines, IL-1β and TNFα were elevated in rats with adjuvant arthritis in relation to disease progression, and if so, to verify the treatment effects of nabumetone (20 mg/kg, p.o.),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012a87823278f834b7086aa87c8bde2c
https://pubmed.ncbi.nlm.nih.gov/10778916

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Protective effects of Aloe barbadensis and Myracrodruon urundeuva on 5-fluorouracil-induced oral mucositis in hamsters

Autor: R. O. Sant’ana, S. G. Fonseca, Ronaldo A. Ribeiro, C. B. Diogenes, G. A. C. Brito, A. Alexandre, R. N. Macedo

Publikováno v: Journal of Clinical Oncology. 25:19606-19606

19606 Introduction: Oral mucositis (OM) is a frequent dose-limiting and costly complication of antineoplastic chemotherapy. It's caractherized by ulcerative lesions and cause pain, restrict food and fluids oral intake and substancial risk for sepsis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1394b262cabb5d47885420cfaef24930
https://doi.org/10.1200/jco.2007.25.18_suppl.19606

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Role of IL-1β and IL-4 in 5-fluorouracil- induced intestinal mucositis in mice

Autor: P. M. Soares, J. S. Mota, G. A. C. Brito, M L P Souza, Fernando Q. Cunha, Ronaldo A. Ribeiro

Publikováno v: Journal of Clinical Oncology. 25:19551-19551

19551 Background: Intestinal mucositis is a frequent side-effect associated to 5-fluorouracil (5-FU) clinical use. The participation of cytokines in the 5-FU- induced intestinal mucositis was not completely elucidated. We evaluated the role of IL-4 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::816920611e224c8c65531e964e3869af
https://doi.org/10.1200/jco.2007.25.18_suppl.19551

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