Výsledky vyhledávání - "G. A. Barclay"

Akademický článek

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.

Autor: Jacob D Estes, Levelle D Harris, Nichole R Klatt, Brian Tabb, Stefania Pittaluga, Mirko Paiardini, G Robin Barclay, Jeremy Smedley, Rhonda Pung, Kenneth M Oliveira, Vanessa M Hirsch, Guido Silvestri, Daniel C Douek, Christopher J Miller, Ashley T Haase, Jeffrey Lifson, Jason M Brenchley

Publikováno v: PLoS Pathogens, Vol 6, Iss 8, p e1001052 (2010)

The chronic phase of HIV infection is marked by pathological activation of the immune system, the extent of which better predicts disease progression than either plasma viral load or CD4(+) T cell count. Recently, translocation of microbial products

Externí odkaz: https://doaj.org/article/b5191db7f6d542828d9bd9b2ceac4d03

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The constituents and mechanisms of generation of ‘endothelial cell—colony forming units’

Autor: Abigail Short, Gareth J. Padfield, G. Robin Barclay, David E. Newby, Olga Tura-Ceide, Kay Samuel, Nicholas L. Mills, Marc Turner

Publikováno v: Cardiovascular Research. 100:288-296

Aims The formation of endothelial cell-colony forming units (EC-CFUs) is increased by vascular injury, although their function in vivo is unclear. We, therefore, examined the constituents of EC-CFUs and the mechanisms of their generation. Methods and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad8207c02283f9cb63e89ab281ae4ba
https://doi.org/10.1093/cvr/cvt182

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Human embryonic stem cells rapidly take up and then clear exogenous human and animal prionsin vitro

Autor: Jean Manson, Enrico Cancellotti, G. Robin Barclay, Kay Samuel, Paul A. De Sousa, Matthew Bishop, Steve Pells, Mark Head, Zuzana Krejciova, James W. Ironside, Marc Turner, Paz Freile

Publikováno v: The Journal of Pathology. 223:635-645

Susceptibility to prion infection involves interplay between the prion strain and host genetics, but expression of the host-encoded cellular prion protein is a known prerequisite. Here we consider human embryonic stem cell (hESC) susceptibility by ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3db238f4dfe3fd5e4a9053b90e37211d
https://doi.org/10.1002/path.2832

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Granulocyte colony‐stimulating factor (G‐CSF) depresses angiogenesis in vivo and in vitro: implications for sourcing cells for vascular regeneration therapy

Autor: John Davies, Huw Roddie, Marc Turner, Olga Tura, G R Barclay, J H Crawford, Patrick W. F. Hadoke, Kay Samuel

Publikováno v: Tura, O, Crawford, J, Barclay, G R, Samuel, K, Hadoke, P W F, Roddie, H, Davies, J & Turner, M L 2010, ' Granulocyte colony-stimulating factor (G-CSF) depresses angiogenesis in vivo and in vitro: implications for sourcing cells for vascular regeneration therapy ', Journal of Thrombosis and Haemostasis, vol. 8, no. 7, pp. 1614-1623 . https://doi.org/10.1111/j.1538-7836.2010.03900.x

Summary. Background: The most common source of hematopoietic progenitor cells (HPCs) for hematopoietic reconstitution comprises granulocyte colony-stimulating factor (G-CSF)-mobilized peripheral blood stem cells (PBSCs). It has been proposed that end

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515eebf640dec53b435db9a0741e0fe3
https://doi.org/10.1111/j.1538-7836.2010.03900.x

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Circulating endothelial progenitor cells are not affected by acute systemic inflammation

Autor: Olga Tura, Marlieke L. A. Haeck, Abigail Short, Elizabeth Freyer, Gareth J. Padfield, David E. Newby, Nicholas L. Mills, G. Robin Barclay

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 298:H2054-H2061

Vascular injury causes acute systemic inflammation and mobilizes endothelial progenitor cells (EPCs) and endothelial cell (EC) colony-forming units (EC-CFUs). Whether such mobilization occurs as part of a nonspecific acute phase response or is a phen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5aa959d7f29dbb97ebf66d36c83f7d7
https://doi.org/10.1152/ajpheart.00921.2009

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Adverse physical effects of alcohol misuse

Autor: J. Barbour, E. Gilvarry, G. A. Barclay, C. P. Day, S. Stewart

Publikováno v: Advances in Psychiatric Treatment. 14:139-151

This article outlines the majority of the adverse physical effects that have been described secondary to the consumption of alcohol at levels above recommended sensible limits. These conditions are cited according to the organ system they belong to.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe083292f62f5644ce0a75cddea5ade8
https://doi.org/10.1192/apt.bp.105.001263

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Three-colour flow cytometric detection of PrP in ovine leukocytes

Autor: G. Robin Barclay, Philip Steele, Jeanie Finlayson, Scott L. Hamilton, Mary-Jo Anderson, Mara Rocchi, Samantha L. Eaton, Francesca Chianini

Publikováno v: Veterinary Immunology and Immunopathology. 116:172-181

PrPc (cellular prion protein, CD230) expression by subpopulations of lymphoid cells has been widely investigated in a variety of species, possibly because of the possible link between transmissible spongiform encephalopathies (TSE) transmission and b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1913cf20c9ed19f4351b97776b1470
https://doi.org/10.1016/j.vetimm.2007.01.012

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Endotoxin immunity and the developmentof the systemic inflammatory responsesyndrome in critically ill children

Autor: Katy Fidler, Monty G. Mythen, Robert C M Stephens, G. R. Barclay, Mark J. Peters, Nigel Klein, Malcolm W. Turner, Garth Dixon, P Wilson

Publikováno v: Intensive Care Medicine. 32:286-294

The systemic inflammatory response syndrome (SIRS) may be triggered by endotoxin. Humans have antibodies directed against the core of endotoxin (endotoxin core antibodies, EndoCAb) that appear to be protective following surgery and in sepsis. We hypo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2001b9ce95391344e953a24071dbab73
https://doi.org/10.1007/s00134-005-0019-z

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Variation in concentration of prion protein in the peripheral blood of patients with variant and sporadic Creutzfeldt-Jakob disease detected by dissociation enhanced lanthanide fluoroimmunoassay and flow cytometry

Autor: Marc Turner, Ian MacGregor, Tim Fagge, Mark Head, James W. Ironside, G. Robin Barclay

Publikováno v: Transfusion. 45:504-513

BACKGROUND: A highly sensitive dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA) and flow cytometry techniques have previously been developed and employed to characterize soluble cellular prion protein (PrPc) expression in whole blood and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6a5249f48436641eb1636e2bda811d
https://doi.org/10.1111/j.0041-1132.2005.04342.x

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