A PHARMACOLOGICAL SYNOPSIS OF SMALL MOLECULES, TOXINS AND CiPA COMPOUNDS TARGETING HUMAN CARDIAC Kv4.3 CHANNELS

Autor: Schombert, Brigitte, Sanson, Camille, Houtmann, Sylvie, Partiseti, Michel, G Andrees Böhme, Sanofi-Aventis R&D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9cc33cfbfbbe96f3d1cc15ca8ead12a9

A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease

Autor: N, Abbas, C B, Lücking, S, Ricard, A, Dürr, V, Bonifati, G, De Michele, S, Bouley, J R, Vaughan, T, Gasser, R, Marconi, E, Broussolle, C, Brefel-Courbon, B S, Harhangi, B A, Oostra, E, Fabrizio, G A, Böhme, L, Pradier, N W, Wood, A, Filla, G, Meco, P, Denefle, Y, Agid, A, Brice

Publikováno v: ResearcherID

Autosomal recessive juvenile parkinsonism (AR-JP, PARK2; OMIM 602544), one of the monogenic forms of Parkinson's disease (PD), was initially described in Japan. It is characterized by early onset (before age 40), marked response to levodopa treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::157dcc8ddb6df2300cf591ce9af63e60
http://hdl.handle.net/11588/483633

RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis

Autor: T, Canton, G A, Böhme, A, Boireau, F, Bordier, S, Mignani, P, Jimonet, G, Jahn, M, Alavijeh, J, Stygall, S, Roberts, C, Brealey, M, Vuilhorgne, M W, Debono, S, Le Guern, M, Laville, D, Briet, M, Roux, J M, Stutzmann, J, Pratt

Publikováno v: The Journal of pharmacology and experimental therapeutics. 299(1)

Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonists are of potential interest for the treatment of certain acute and chronic neurodegenerative diseases, including amyotrophic lateral sclerosis. Here, we desc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::659f1d840de5b8243503894e4bec085f
https://pubmed.ncbi.nlm.nih.gov/11561094

Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury

Autor: S, Parmentier, G A, Böhme, D, Lerouet, D, Damour, J M, Stutzmann, I, Margaill, M, Plotkine

Publikováno v: British journal of pharmacology. 127(2)

1. The aim of this study was to investigate the effect of N-(3-(aminomethyl)benzyl)acetamidine (1400W), a selective inhibitor of inducible calcium-independent nitric oxide synthase (iNOS), on the functional and histopathological outcomes of experimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2987e2ecdbdf5feeaf1ebe30e51b2db4
https://pubmed.ncbi.nlm.nih.gov/10385257

NITRIC OXIDE, SYNAPTIC PLASTICITY AND MEMORY FORMATION IN THE BRAIN

Autor: G. Andrees Böhme

Publikováno v: Macromolecular Interplay In Brain Associative Mechanisms ISBN: 9789810232122
Macromolecular Interplay In Brain Associative Mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a112c7fad8d8942e2b8fbea3b07766c0
https://doi.org/10.1142/9789812816894_0012