Zobrazeno 1 - 10
of 1 026
pro vyhledávání: '"G-protein coupled estrogen receptor"'
Autor:
Maryam Mohammad-Sadeghipour, Mohammad Hadi Nematollahi, Hassan Ahmadinia, Mohammad Reza Hajizadeh, Mehdi Mahmoodi
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 5, Pp 606-621 (2024)
Background and purpose: This study investigated modulating the G protein-coupled estrogen receptor (GPER) on the IRElα/TXNIP pathway and its role in drug resistance in MDA-MB231 cells. Experimental approach: To determine the optimal concentrations o
Externí odkaz:
https://doaj.org/article/a5a44b0e0c494b0aa67c886b131b425d
Publikováno v:
陆军军医大学学报, Vol 46, Iss 12, Pp 1369-1377 (2024)
Objective To investigate the mechanism by which G protein-coupled estrogen receptor (GPER) reduces retinal neovascularisation in oxygen-induced retinopathy (OIR) in newborn mice. Methods A total of 42 newborn mice were randomly divided into normoxic
Externí odkaz:
https://doaj.org/article/eb97b9f60ccb422ea7240da500b45e6b
Autor:
Marianna Talia, Francesca Cirillo, Domenica Scordamaglia, Marika Di Dio, Azzurra Zicarelli, Salvatore De Rosis, Anna Maria Miglietta, Carlo Capalbo, Ernestina Marianna De Francesco, Antonino Belfiore, Fedora Grande, Bruno Rizzuti, Maria Antonietta Occhiuzzi, Giancarlo Fortino, Antonella Guzzo, Gianluigi Greco, Marcello Maggiolini, Rosamaria Lappano
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background The cyclin D1-cyclin dependent kinases (CDK)4/6 inhibitor palbociclib in combination with endocrine therapy shows remarkable efficacy in the management of estrogen receptor (ER)-positive and HER2-negative advanced breast cancer (B
Externí odkaz:
https://doaj.org/article/953c860ef51d47f89a770236fa68ff4a
Autor:
Francesca Cirillo, Asia Spinelli, Marianna Talia, Domenica Scordamaglia, Maria Francesca Santolla, Fedora Grande, Bruno Rizzuti, Marcello Maggiolini, Céline Gérard, Rosamaria Lappano
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Estetrol (E4) is a natural estrogen produced by the fetal liver during pregnancy. Due to its favorable safety profile, E4 was recently approved as estrogenic component of a new combined oral contraceptive. E4 is a selective ligand
Externí odkaz:
https://doaj.org/article/095d6167bd79405e95e77b5a69c80c94
Autor:
Tingting Yang, Zhen Qiu, Jiaming Shen, Yutian He, Longxiang Yin, Li Chen, Jiayu Yuan, Junjie Liu, Tao Wang, Zhenzhou Jiang, Changjiang Ying, Sitong Qian, Jinfang Song, Xiaoxing Yin, Qian Lu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 9, Pp 100962- (2024)
Benign prostatic hyperplasia (BPH) is one of the major chronic complications of type 2 diabetes mellitus (T2DM), and sex steroid hormones are common risk factors for the occurrence of T2DM and BPH. The profiles of sex steroid hormones are simultaneou
Externí odkaz:
https://doaj.org/article/cdb639895990402a864262164e29e7cd
Autor:
Zhang, Hui 1, Li, Chan 1, Lu, Sihai, Wu, Hao, Li, Jingmei, Liu, Qingyang, Yan, Yutong, Tang, Yaju, Xu, Rui, Zhao, Xiaoe, Pan, Menghao, Wei, Qiang, Peng, Sha ⁎, Ma, Baohua ⁎
Publikováno v:
In International Journal of Biological Macromolecules February 2025 290
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/d8932bafd25946afb29651e3b0142145
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
IntroductionEstrogen has emerged as a multifaceted signaling molecule in the retina, playing an important role in neural development and providing neuroprotection in adults. It interacts with two receptor types: classical estrogen receptors (ERs) alp
Externí odkaz:
https://doaj.org/article/bfd066a394c54794a339b7434817f474
Autor:
Jianchao Mao, Yongkun Guo, Huanhuan Li, Hongfei Ge, Chao Zhang, Hua Feng, Jun Zhong, Rong Hu, Xinjun Wang
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26909- (2024)
Background: Early brain injury (EBI) caused by inflammatory responses in acute phase of Intracerebral hemorrhage (ICH) plays a vital role in the pathological progression of ICH. Increasing evidences demonstrate A1 reactive astrocytes are associated w
Externí odkaz:
https://doaj.org/article/7ee7aa9f15ed42e69bdca9d837c83c99
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Triple-negative breast cancer (TNBC) is a biologically and clinically heterogeneous disease. The G protein-coupled estrogen receptor (GPER) plays a crucial role in mediating the effect of estrogen and estrogen-like compounds in TNBC cells. Compared w
Externí odkaz:
https://doaj.org/article/899e2ad7b8dc4802ad4694b1c36d4a1c