Zobrazeno 1 - 10
of 43
pro vyhledávání: '"G W Litman"'
Publikováno v:
The Journal of Immunology. 157:1544-1550
Xenopus laevis is a unique model for studying the ontogenetic development of immune functions. A short primer PCR amplification method was employed to amplify fragments from Xenopus genomic DNA that are related to Ig light chains and TCR. One fragmen
Publikováno v:
The Journal of Immunology. 157:1569-1575
Mammalian CD45 is a transmembrane protein tyrosine phosphatase expressed by all nucleated cells of hematopoietic origin. In lymphocytes, CD45 is required for Ag-induced signal transduction due to its ability to positively regulate Src family members.
Publikováno v:
The Journal of Immunology. 156:2458-2464
The genetic complexity of the expressed TCR Vbeta repertoire in Heterodontus francisci, the horned shark, a member of the most phylogenetically primitive vertebrate class in which TCR genes have been identified, is addressed. The sequences of 55 sple
Publikováno v:
Immunological reviews. 181
Novel immune-type receptor (NITR) genes, which initially were identified in the Southern pufferfish (Spheroides nephelus), encode products which consist of an extracellular variable (V) and V-like C2 (V/C2) domain, a transmembrane region, and a cytop
Publikováno v:
Genesis (New York, N.Y. : 2000). 27(4)
The extraembryonic ectoderm development (exed) mutant phenotype was described in mice homozygous for the c(6H) deletion, a radiation-induced deletion in the tyrosinase region of mouse Chromosome 7. These mutants fail to gastrulate and die around embr
Autor:
J A, Yoder, G W, Litman
Publikováno v:
Current topics in microbiology and immunology. 248
Immunoglobulin gene diversity has been characterized to varying degrees in modern representatives of all of the major radiations of cartilaginous fish. A pattern of overall chromosomal relationships of the various types of joined and unjoined Ig gene
Autor:
M, Vihinen, R A, Brooimans, S P, Kwan, H, Lehväslaiho, G W, Litman, H D, Ochs, I, Resnick, J H, Schwaber, I, Vorĕchovsky, C I, Smith
Publikováno v:
Immunology today. 17(11)
Publikováno v:
Molecular medicine (Cambridge, Mass.). 2(5)
BACKGROUND: X-linked agammaglobulinemia (XLA) is a severe, life-threatening disease characterized by failure of B cell differentiation and antibody production and is associated with mutations in Bruton's tyrosine kinase (Btk). The proband in this stu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(4)
Xenopus laevis is a unique model for studying the ontogenetic development of immune functions. A short primer PCR amplification method was employed to amplify fragments from Xenopus genomic DNA that are related to Ig light chains and TCR. One fragmen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(7)
The genetic complexity of the expressed TCR Vbeta repertoire in Heterodontus francisci, the horned shark, a member of the most phylogenetically primitive vertebrate class in which TCR genes have been identified, is addressed. The sequences of 55 sple