Zobrazeno 1 - 4
of 4
pro vyhledávání: '"G W, Verhaegh"'
Autor:
M J, Bussemakers, A, van Bokhoven, G W, Verhaegh, F P, Smit, H F, Karthaus, J A, Schalken, F M, Debruyne, N, Ru, W B, Isaacs
Publikováno v:
Cancer research. 59(23)
Prostate cancer is the most commonly diagnosed malignancy and the second leading cause of cancer-related deaths in the Western male population. Despite the tremendous efforts that have been made to improve the early detection of this disease and to d
Publikováno v:
Molecular carcinogenesis. 21(3)
The transcription factor p53 controls the proliferation and survival of cells exposed to DNA damage. The specific DNA-binding domain of p53 (residues 102-292) has a complex tertiary structure that is stabilized by zinc. In this study, we showed that
Autor:
G W, Verhaegh, W, Jongmans, N G, Jaspers, A T, Natarajan, M, Oshimura, P H, Lohman, M Z, Zdzienicka
Publikováno v:
American journal of human genetics. 57(5)
Inhibition of replicative DNA synthesis following gamma-irradiation is observed in eukaryotic cells but is defective in cells derived from patients with the cancer-prone inherited disorder ataxia-telangiectasia (A-T) and in A-T-like Chinese hamster c
Publikováno v:
International journal of radiation biology. 66
In order to isolate a human gene complementing the defect in A-T-like hamster cell mutants, the mutants were used as recipients for genomic DNA transfection, using either HeLa chromosomal DNA or DNA from a human cosmid library. Three primary transfor