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Autor:
G Vanden Heauvel, Amanda Fletcher, D Kearn, Richard C. Baybutt, F Raza, J Buursma, Agostino Molteni, Safia Livingston, Betty Herndon
Publikováno v:
The FASEB Journal. 29
CUX1 is a transcriptional repressor gene in the network controlling G1-S phase transition. It represses the expression of the cyclin kinase (CK1) inhibitors p21 and p27. Transgenic mice constitutively expressing CUX1 develop multiorgan damage consequ