Zobrazeno 1 - 10
of 313
pro vyhledávání: '"G Ulrich Nienhaus"'
Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells
Autor:
Giulia Ambrosi, Oksana Voloshanenko, Antonia F Eckert, Dominique Kranz, G Ulrich Nienhaus, Michael Boutros
Publikováno v:
eLife, Vol 11 (2022)
Wnt signaling plays important roles in development, homeostasis, and tumorigenesis. Mutations in β-catenin that activate Wnt signaling have been found in colorectal and hepatocellular carcinomas. However, the dynamics of wild-type and mutant forms o
Externí odkaz:
https://doaj.org/article/6a4cebd9d4ab403c9ac8d82a751b22e4
Autor:
Benjamin Schott, Manuel Traub, Cornelia Schlagenhauf, Masanari Takamiya, Thomas Antritter, Andreas Bartschat, Katharina Löffler, Denis Blessing, Jens C Otte, Andrei Y Kobitski, G Ulrich Nienhaus, Uwe Strähle, Ralf Mikut, Johannes Stegmaier
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 4, p e1006128 (2018)
State-of-the-art light-sheet and confocal microscopes allow recording of entire embryos in 3D and over time (3D+t) for many hours. Fluorescently labeled structures can be segmented and tracked automatically in these terabyte-scale 3D+t images, result
Externí odkaz:
https://doaj.org/article/7f33f09408ae4be590227c09b01c12b0
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202052 (2018)
Dysferlin (Dysf) and mitsugumin53 (MG53) are two key proteins involved in membrane repair of muscle cells which are efficiently recruited to the sarcolemma upon lesioning. Plasma membrane localization and recruitment of a Dysf fragment to membrane le
Externí odkaz:
https://doaj.org/article/5eca6b2c17d64878b3a7484e3314da5a
Autor:
Johannes Stegmaier, Jens C Otte, Andrei Kobitski, Andreas Bartschat, Ariel Garcia, G Ulrich Nienhaus, Uwe Strähle, Ralf Mikut
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90036 (2014)
Automated analysis of multi-dimensional microscopy images has become an integral part of modern research in life science. Most available algorithms that provide sufficient segmentation quality, however, are infeasible for a large amount of data due t
Externí odkaz:
https://doaj.org/article/2ba94cf77a784a468934eb4225519ff9
Autor:
Simone Kredel, Franz Oswald, Karin Nienhaus, Karen Deuschle, Carlheinz Röcker, Michael Wolff, Ralf Heilker, G Ulrich Nienhaus, Jörg Wiedenmann
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4391 (2009)
A monomeric variant of the red fluorescent protein eqFP611, mRuby, is described. With excitation and emission maxima at 558 nm and 605 nm, respectively, and a large Stokes shift of 47 nm, mRuby appears particularly useful for imaging applications. Th
Externí odkaz:
https://doaj.org/article/a78ff627c6f9449e8a1031c882d8b63a
Autor:
Alexander Vogt, Cecilia D'Angelo, Franz Oswald, Andrea Denzel, Charles H Mazel, Mikhail V Matz, Sergey Ivanchenko, G Ulrich Nienhaus, Jörg Wiedenmann
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3766 (2008)
A colorful variety of fluorescent proteins (FPs) from marine invertebrates are utilized as genetically encoded markers for live cell imaging. The increased demand for advanced imaging techniques drives a continuous search for FPs with new and improve
Externí odkaz:
https://doaj.org/article/28974503929f4b6c899b8d34c566d68b
Autor:
Daniel Englert, Eva-Maria Burger, Franziska Grün, Mrigank S. Verma, Jens Lackner, Marko Lampe, Bastian Bühler, Janin Schokolowski, G. Ulrich Nienhaus, Andres Jäschke, Murat Sunbul
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed ce
Externí odkaz:
https://doaj.org/article/9497349644eb460a9fa92b4db02b0bfb
Autor:
Bernd Jahrsdörfer, Hubert Schrezenmeier, Peter Möller, Rolf Kreienberg, Thomas Simmet, G. Ulrich Nienhaus, Oleg Lunov, Ramin Lotfi, Dorit Fabricius, Frank Reister, Thamara Beyer, Thomas F.E. Barth, Christof Kaltenmeier, Magdalena Hagn, Kai Sontheimer, Karen Dahlke, Stefanie Lindner
PDF file - 182K, Supplemental Figure 1. B cells activated with IL-21 and anti-BCR secrete enzymatically active granzyme B. Supplemental Figure 2. Interleukin 21 in the absence of B cells does not suppress T cell proliferation. Supplemental Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e0bf137b5ad341824f146517ce1bf2
https://doi.org/10.1158/0008-5472.22399989.v1
https://doi.org/10.1158/0008-5472.22399989.v1
Autor:
Bernd Jahrsdörfer, Hubert Schrezenmeier, Peter Möller, Rolf Kreienberg, Thomas Simmet, G. Ulrich Nienhaus, Oleg Lunov, Ramin Lotfi, Dorit Fabricius, Frank Reister, Thamara Beyer, Thomas F.E. Barth, Christof Kaltenmeier, Magdalena Hagn, Kai Sontheimer, Karen Dahlke, Stefanie Lindner
MOV file - 3136K, Supplemental Video 1. B cells transfer active GrB to T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393d7b046061f65289ef28d393ff61c8
https://doi.org/10.1158/0008-5472.22399983
https://doi.org/10.1158/0008-5472.22399983
Autor:
Daniel Englert, Eva-Maria Burger, Jens Lackner, Marko Lampe, Bastian Bühler, Franziska Grün, Janin Schokolowski, G. Ulrich Nienhaus, Andres Jäschke, Murat Sunbul
Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cbd5af8f9a0a44382e66cfacfd0872f
https://doi.org/10.1101/2022.10.24.513449
https://doi.org/10.1101/2022.10.24.513449