Zobrazeno 1 - 10
of 731
pro vyhledávání: '"G Tolman"'
Autor:
Francis, E. K.
Publikováno v:
The American Catholic Sociological Review, 1952 Oct 01. 13(3), 179-181.
Externí odkaz:
https://www.jstor.org/stable/3707173
Autor:
Pete A. Williams, Catherine E. Braine, Krishnakumar Kizhatil, Nicole E. Foxworth, Nicholas G. Tolman, Jeffrey M. Harder, Rebecca A. Scott, Gregory L. Sousa, Alyssa Panitch, Gareth R. Howell, Simon W. M. John
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-23 (2019)
Abstract Background Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. Recent work in animal models suggests that a critical neuroinflammatory event damages retinal ganglion cell axons in the optic nerve head
Externí odkaz:
https://doaj.org/article/1d88fd54288e4ead90e9c80f9e2ea71f
Autor:
Nicholas G. Tolman, Revathi Balasubramanian, Danilo G. Macalinao, Alison L. Kearney, Katharine H. MacNicoll, Christa L. Montgomery, Wilhelmine N. de Vries, Ian J. Jackson, Sally H. Cross, Krishnakumar Kizhatil, K. Saidas Nair, Simon W. M. John
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better u
Externí odkaz:
https://doaj.org/article/c6b3c570e59e4dcfbb215df5e8ffb694
Autor:
Cassandre Labelle-Dumais, Goutham Pyatla, Seyyedhassan Paylakhi, Nicholas G. Tolman, Syed Hameed, Yusef Seymens, Eric Dang, Anil K. Mandal, Sirisha Senthil, Rohit C. Khanna, Meha Kabra, Inderjeet Kaur, Simon W. M. John, Subhabrata Chakrabarti, K. Saidas Nair
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 5 (2020)
Glaucoma is a leading cause of blindness, affecting up to 70 million people worldwide. High intraocular pressure (IOP) is a major risk factor for glaucoma. It is well established that inefficient aqueous humor (AqH) outflow resulting from structural
Externí odkaz:
https://doaj.org/article/000031ab42834a4b8f1e7981190ae637
Autor:
Hélène Choquet, Seyyedhassan Paylakhi, Stephen C. Kneeland, Khanh K. Thai, Thomas J. Hoffmann, Jie Yin, Mark N. Kvale, Yambazi Banda, Nicholas G. Tolman, Pete A. Williams, Catherine Schaefer, Ronald B. Melles, Neil Risch, Simon W. M. John, K. Saidas Nair, Eric Jorgenson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Primary open-angle glaucoma (POAG) leads to progressive vision loss. Here, Choquet et al. perform genome-wide association analysis for POAG in a multi-ethnic cohort, identify a total of nine novel genetic loci and show relevant function of FMNL2 and
Externí odkaz:
https://doaj.org/article/3cb4f5850708427babaf362b4c3b7b49
Autor:
K. Saidas Nair, Mihai Cosma, Narayanan Raghupathy, Michael A. Sellarole, Nicholas G. Tolman, Wilhelmine de Vries, Richard S. Smith, Simon W. M. John
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 8, Pp 863-871 (2016)
A variety of inherited animal models with different genetic causes and distinct genetic backgrounds are needed to help dissect the complex genetic etiology of glaucoma. The scarcity of such animal models has hampered progress in glaucoma research. He
Externí odkaz:
https://doaj.org/article/51f8c696944d4be89b70c38f78bb5165
Autor:
Seyyedhassan Paylakhi, Cassandre Labelle-Dumais, Nicholas G Tolman, Michael A Sellarole, Yusef Seymens, Joseph Saunders, Hesham Lakosha, Wilhelmine N deVries, Andrew C Orr, Piotr Topilko, Simon Wm John, K Saidas Nair
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007244 (2018)
A mismatch between optical power and ocular axial length results in refractive errors. Uncorrected refractive errors constitute the most common cause of vision loss and second leading cause of blindness worldwide. Although the retina is known to play
Externí odkaz:
https://doaj.org/article/f1ef13975e68440b9b2f280a329c6bde
Publikováno v:
In Journal of Heart and Lung Transplantation 1999 18(1):47-47
Autor:
Krishnakumar Kizhatil, Danilo G. Macalinao, Sally H. Cross, Wilhelmine N. de Vries, Ian J. Jackson, K. Saidas Nair, Nicholas G. Tolman, Alison L. Kearney, Christa L. Montgomery, Katharine H. MacNicoll, Revathi Balasubramanian, Simon W. M. John
Publikováno v:
Tolman, NG, Balasubramanian, R, Macalinao, D G, Kearney, A L, MacNicoll, KH, Montgomery, C L, de Vries, WN, Jackson, I J, Cross, S, Kizhatil, K, Nair, KS & John, SWM 2021, ' Genetic background modifies vulnerability to glaucoma related phenotypes in Lmx1b mutant mice ', Disease Models and Mechanisms . https://doi.org/10.1242/dmm.046953
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e75d0cad79578c4d4f4a32c26eefdf6
https://doi.org/10.1242/dmm.046953
https://doi.org/10.1242/dmm.046953
Autor:
Nicholas G, Tolman, Revathi, Balasubramanian, Danilo G, Macalinao, Alison L, Kearney, Katharine H, MacNicoll, Christa L, Montgomery, Wilhelmine N, de Vries, Ian J, Jackson, Sally H, Cross, Krishnakumar, Kizhatil, K Saidas, Nair, Simon W M, John
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Variants in the LIM homeobox transcription factor 1-beta (LMX1B) gene predispose individuals to elevated intraocular pressure (IOP), a key risk factor for glaucoma. However, the effect of LMX1B mutations varies widely between individuals. To better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c342cda45eb1b5f9f6dc046d7c6df31d
https://pubmed.ncbi.nlm.nih.gov/33462143
https://pubmed.ncbi.nlm.nih.gov/33462143