Výsledky vyhledávání

Diurnal changes in plasma levels of 2-pyrrolidinone determined by isotope dilution mass spectrometry

Autor: Bg Wolthers, Ga Vandenberg, Faj Muskiet, Ra Dezeeuw, S Banghman, G T Nagel

Publikováno v: Journal of Chromatography A. 550:239-245

A new capillary gas chromatographic method with mass spectrometric detection for the determination of 2-pyrrolidinone was developed. Using quantification based on stable isotope dilution mass spectrometry by monitoring selected ions in the ammonia ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef3d22d41b980ad995f782299bd51dda
https://doi.org/10.1016/s0021-9673(01)88541-1

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Phenylketonuria - The in vivo hydroxylation rate of phenylalanine into tyrosine is decreased

Autor: Frans Stellaard, van FrancJan Spronsen, Rudolphus Berger, G T Nagel, Hsa Heymans, Dirk Reijngoud, Gerrit Smit

Publikováno v: The Journal of Clinical Investigation, 101(12), 2875-2880. AMER SOC CLINICAL INVESTIGATION INC
Journal of clinical investigation, 101(12), 2875-2880. The American Society for Clinical Investigation
University of Groningen

In phenylketonuria (PKU), the enzyme phenylalanine hydroxylase is deficient, resulting in a decreased conversion of phenylalanine (Phe) into tyrosine (Tyr). The severity of the disease is expressed as the tolerance for Phe at 5 yr of age. In PKU pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91afa8827d3a5ebc69161d304b86266f
https://research.rug.nl/en/publications/7f3df157-675d-45be-b42a-7e2e265fd47a

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Isotope dilution ammonia chemical ionization mass fragmentographic analysis of urinary 3-O-methylated catecholamine metabolites. Rapid sample clean-up by derivatization and extraction of lyophilized samples

Autor: I P, Kema, G, Meiborg, G T, Nagel, G J, Stob, F A, Muskiet

Publikováno v: Journal of chromatography. 617(2)

We developed a method for simultaneous quantification of the urinary 3-O-methylated catecholamine metabolites 3-methoxytyramine, normetanephrine and metanephrine by stable isotope-dilution ammonia chemical ionization mass fragmentography. Prepurifica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e6b1ec8053d5cfecb476dec93e4acc5
https://pubmed.ncbi.nlm.nih.gov/8408382

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Determination of 3-methoxy-4-hydroxyphenylpyruvic acid, 3,4-dihydroxyphenylethylene glycol, and 3,4-dihydroxyphenylmandelic acid in urine by mass fragmentography, with use of deuterium-labeled internal standards

Autor: Bg Wolthers, D C Fremouw-Ottevangers, F A Muskiet, G T Nagel, J A de Vries

Publikováno v: Clinical Chemistry, 24(11), 2001-2008. AMER ASSOC CLINICAL CHEMISTRY

We report the determination of 3-methoxy-4-hydroxyphenylpyruvic acid, 3,4-dihydroxyphenylmandelic acid, and 3,4-dihydroxyphenylethylene glycol in urine, by use of gas chromatography/mass spectrometry in combination with a simple purification method a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66463a412f432a4a94e9fdd1e1b7e1b4
https://doi.org/10.1093/clinchem/24.11.2001

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Determination of catecholamines and their 3-O-methylated metabolites in urine by mass fragmentography with use of deuterated internal standards

Autor: A M Gerding, F A Muskiet, D C Fremouw-Ottevangers, Bg Wolthers, C G Thomasson, G T Nagel

Publikováno v: Clinical Chemistry, 25(3), 453-460. AMER ASSOC CLINICAL CHEMISTRY

We report the determination of catecholamines (dopamine, norepinephrine, and epinephrine) and their 3-O-methylated metabolites (3-methoxytyramine, normetanephrine, and metanephrine) in urine by gas chromatography/mass spectrometry, with use of stable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168bdf09cd4c389f54d9465373be69e1
https://doi.org/10.1093/clinchem/25.3.453

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Mass-fragmentographic determination of catecholamine metabolites in amniotic fluid and its possible clinical usefulness

Autor: F A Muskiet, G T Nagel, H. J. Jeuring, Bg Wolthers, H W de Bruyn

Publikováno v: Clinical Chemistry. 24:1899-1902

We describe the determination of 3-methoxy-4-hydroxy-phenylacetic acid, 3-methoxy-4-hydroxyphenylamandelic acid, and 3-methoxy-4-hydroxyphenylethylene glycol in amniotic fluid by means of mass fragmentography, with use of deuterated internal standard

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b0e91e4af13bbe3b801de68b39e3880
https://doi.org/10.1093/clinchem/24.11.1899

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Mass-fragmentographic determination of catecholamine metabolites in amniotic fluid and its possible clinical usefulness

Autor: F A, Muskiet, H J, Jeuring, G T, Nagel, H W, de Bruyn, B G, Wolthers

Publikováno v: Clinical chemistry. 24(11)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ff0ae8bef787fde61b0485ee20e2df3
https://pubmed.ncbi.nlm.nih.gov/709817

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Determination of 4-O-methylated catecholamine metabolites in urine by mass fragmentography

Autor: F A, Muskiet, D C, Fremouw-Ottevangers, G T, Nagel, B G, Wolthers

Publikováno v: Clinical chemistry. 25(10)

We describe the determination of the 4-O-methylated catecholamine metabolites 4-methoxy-3-hydroxyphenylacetic acid (iso-HVA), 4-methoxy-3-hydroxyphenylmandelic acid (iso-VMA) and 4-methoxy-3-hydroxyphenylethylene glycol (iso-MOPEG) in urine with use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::457bc32b96e0e2c0228401b42f99d4b6
https://pubmed.ncbi.nlm.nih.gov/476919

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