Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a randomised controlled trial

Autor: C. J. Vickery, M. J. Lamparelli, R. Gupta, G. Maskell, A. C. Bateman, M. L. Hughes, Michael Braun, D. A. Agbamu, H. O'Neill, J. H. Scholefield, W. Faux, A. S. Myint, C. Macklin, H. J. Pearson, P. Richman, Geraint T. Williams, S. Sukumar, A. Kawesha, J. Robinson, Dion Morton, Caroline Finlayson, M. Saeed, A. Anathhanam, D. M. Melville, J. Whalley, Rizvana Ahmad, V. Howarth, E. Favill, Jacob G. Scott, M. Scott, D. Eason, S. M. Ahmad, Rajarshi Roy, M. Gupta, F. Lofts, N. Beharry, N. Lees, M. Charig, A. Buxton, Fiona Campbell, K. G. Walker, M. Train, P. Nichols, J. Mathew, G. Stenhouse, J. Orrell, P. Burn, D. Peake, S. P. Lake, D. Ilsley, A. J. Watson, A Mayer, A C Wotherspoon, David J. Smith, A. K. Thompson, J. Gutmann, W. K. Dunn, J. Huang, Tracy E Roberts, L. Meleagros, D. Cowlishaw, Angela E Taylor, P. Chandran, C. Bronder, B. Fozard, Jurjees Hasan, S. J. Needham, Rob Glynne-Jones, Jonathan Wadsley, F. Adab, J. Ostrowski, Andrew Bateman, I. T. Saeed, David Cunningham, E. Loveday, David Ferry, A. Hartley, K. Sleigh, A. Page, I. C. Ilesley, P. Cohen, D. Whillis, Phillipe Taniere, Paul J. Finan, S. Pritchard, S. Lee, A. Zaitoun, J. A. Rees, G. Langman, G. Howarth, D. Pai, D. Blunt, R. Osborne, W. Atkinson, D. Barber, O. A. Ogunbiyi, J. Harrison, H. Burnett, V. Sundaresan, S. Hayes, J. Livingstone, Simon Gollins, F. Daniel, G. Kurien, C. Holland, I. Britton, A. Sherif, Clifton D. Fuller, D. Shareef, Matthew T. Seymour, J. McCutcheon, C. Phelan, Charles Lowdell, R. M. Blaquiere, J. Alexander, A. Hamid, Sherif Raouf, A. Baxter, Tamas Hickish, Joanne Hornbuckle, A. Pallan, J. R.G. Bell, Graham Branagan, D. Tolan, A. Moss, J. Hampton, C. W. Hendrickse, D. Furniss, T. Burdge, Carolyn S. Hall, J. Watkins, C. Barlow, J. Hartley, P. Rooney, B. Pravee, Anne Pullyblank, C. Corr, A. Chiphang, J. Walther, Paris P. Tekkis, M. J. Dworkin, D. Eaton, R. Hagger, J. Mikel, A. Coup, M. Peters, S. Muzaffar, Sujal R. Desai, D. Tarver, C. Ramsey, Sarah Smith, J. Geraghty, N. Mapstone, Corran Roberts, John Bridgewater, S. Amin, P. Dawson, Vanessa Potter, C. J. Walsh, M. Pitt, N. Woodcock, S. Ramesh, Charlotte Rees, Nigel Scott, N. Steven, A. Maw, D. P. O'Leary, David Farrugia, S. Cook, D. Tsang, M. Callaway, P. Taylor, Andrew J. Hall, S. R. Muthuramalingam, S. A.M. Mangalika, N. Cruickshank, U. Raja, M. Dobson, C. Bale, R. W. Talbot, M. Qaiyum, M. Crabtree, Stephen H D Jackson, J. Hyde, S. Snape, Richard J. Ellis, R. Borgstein, A. Higginson, M. Thyveetil, Michael Thomas, A. Lowe, W. Partridge, Gina Brown, A. W. MacDonald, O. Lalude, M. Clwyd, Brendan J. Moran, G. T. Smith, Samir Mehta, B. T. Ismail, R. Donovan, P. Kitsanta, E. Kweka, N. Scot, K. Hopkins, N. Rooney, A. L. Desai, S. Jain, N. Wong, T. Iveson, Rubin Soomal, R. D. Taraporewalla, A. Clarke, J. Brittenden, S. Dundas, Marcia Hall, J. Denson, N. Day, Simon Aird Grumett, R. Church, M. Zeiderman, M. Steward, Daniel Swinson, S. Susnerwala, Stephen Falk, A. Malhotra, D. White, N. Pranesh, J. Haselden, James Hill, D. Scullion

Publikováno v: The Lancet Oncology. 13:1152-1160

Background Preoperative (neoadjuvant) chemotherapy and radiotherapy are more effective than similar postoperative treatment for oesophageal, gastric, and rectal cancers, perhaps because of more effective micrometastasis eradication and reduced risk o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c179d79bec2b424eaa6df5c9ef3b22
https://doi.org/10.1016/s1470-2045(12)70348-0

Temperature Dependence of Electrocommunication Signals and Their Underlying Neural Rhythms in the Weakly Electric Fish, Apteronotus leptorhynchus

Autor: Kent D. Dunlap, G T Smith, A Yekta

Publikováno v: Brain, Behavior and Evolution. 55:152-162

Weakly electric fish emit an electric communication signal that is controlled by a highly specialized neural circuit. In Apteronotus, the continuous electric organ discharge (EOD) is generated by electrotonically coupled neurons in the hindbrain pace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8deb079195d16f076b25884ff505d9c
https://doi.org/10.1159/000006649

Detection of alcohol misusing patients in accident and emergency departments: the Paddington alcohol test (PAT)

Autor: Stephen E Wright, R. Touquet, S. G. T. Smith, N. Das Gupta

Publikováno v: Emergency Medicine Journal. 13:308-312

OBJECTIVE: To develop an effective but practical screening questionnaire for use by accident and emergency (AE and to integrate an alcohol health worker (AHW) into A&E to provide counselling for referred patients. METHODS: Two pilot studies for adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f4ac057178601018ab74f0e83001085
https://doi.org/10.1136/emj.13.5.308

Transition across polymorphic phenotypes observed in a male Sternarchogiton nattereri (Gymnotiformes: Apteronotidae)

Autor: W W, Ho, C R, Turner, G T, Smith

Publikováno v: Journal of fish biology. 83(3)

A transition between polymorphic phenotypes was observed within a single male Sternarchogiton nattereri. This individual was initially toothless, but developed into a toothed phenotype characterized by a swollen distal upper jaw and distinctive exter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::598a33c47a753325770593beaa727cc4
https://pubmed.ncbi.nlm.nih.gov/23991881

Where do you draw the line? Points to consider when implementing the FDA method validation guidance on quantifying chromatographic peaks

Autor: Howard Hill, G. T. Smith, R. R. Brodie, J. Smeraglia

Publikováno v: Chromatographia. 55:S79-S81

The advent of automated/computerised data collection and processing systems has minimised the amount of manual intervention and human decision-making required to determine the baseline for a chromatographic peak. There remain however, a number of act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a78eed14fbdbb6dcb09b2571fd00c106
https://doi.org/10.1007/bf02493358