Zobrazeno 1 - 10
of 15
pro vyhledávání: '"G T, Layton"'
Autor:
Ute-Christiane Meier, Andrew J. McMichael, John I. Bell, M G Hunter, Sabrina Tafuro, P R Dunbar, E Y Jones, G T Layton
Publikováno v:
European Journal of Immunology. 31:440-449
Engineered MHC-peptide targets capable of inducing recognition by CTL may prove useful in designing vaccines for infectious disease and cancer. We tested whether peptides directly linked to beta2-microglobulin (beta2m) could complex with human HLA cl
Autor:
N.C Doherty, D Krige, H Davies, G T Layton, S Myint, D.K Jones, E L Berrie, C.A Ryan, T J French, H.R Mills, Dennis J. McCance
Publikováno v:
Virus Research. 49:187-191
The majority of condylomata acuminata (anogenital warts) are caused by infection with Human Papilloma Virus type 6 (HPV-6). We have sequenced the HPV-6 early genes, E1^E4, E6 and E7 from wart biopsy DNA samples sourced from the UK and USA and derived
Autor:
G T Layton, S J Harris, A J Gearing, M Hill-Perkins, J S Cole, J C Griffiths, N R Burns, A J Kingsman, S E Adams
Publikováno v:
The Journal of Immunology. 151:1097-1107
In general, it has proven difficult to induce CTL responses using simple proteins or peptides without resorting to specialized adjuvants. In this study we show that particulate polymeric Ag in the form of hybrid Ty virus-like particles carrying the V
Autor:
G T Layton, T J French, E L Berrie, Sally Adams, Stephen J. Harris, J C Griffiths, A J Kingsman, Nigel R. Burns
Publikováno v:
Journal of Virology. 67:3191-3198
In attempts to increase the immunogenicity of recombinant antigens, a number of particulate antigen presentation systems have been developed. In this study, we used human immunodeficiency virus Gag particles as carriers for the human immunodeficiency
Autor:
S, Tafuro, U C, Meier, P R, Dunbar, E Y, Jones, G T, Layton, M G, Hunter, J I, Bell, A J, McMichael
Publikováno v:
European journal of immunology. 31(2)
Engineered MHC-peptide targets capable of inducing recognition by CTL may prove useful in designing vaccines for infectious disease and cancer. We tested whether peptides directly linked to beta2-microglobulin (beta2m) could complex with human HLA cl
Autor:
M D, Welsh, D R, Harper, M, Garcia-Valcarcel, W J, Fowler, C, Aitken, D J, Jeffries, G T, Layton
Publikováno v:
Journal of medical virology. 59(1)
Yeast Ty virus-like particles (VLPs) containing viral protein inserts have previously been shown to be potent immunogens, inducing both humoral and cell mediated immunity (CMI). The antigenicity of hybrid VLPs containing fragments of the varicella-zo
Publikováno v:
Journal of medical virology. 53(4)
Herpesviruses produce assembly proteins (AP) that act as scaffolding proteins for the assembly of the viral capsids. The products of the assemblin gene, which encodes both maturational protease and AP, have been established for herpes simplex virus t
Autor:
G T, Layton, S J, Harris, A J, Gearing, M, Hill-Perkins, J S, Cole, J C, Griffiths, N R, Burns, A J, Kingsman, S E, Adams
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(2)
In general, it has proven difficult to induce CTL responses using simple proteins or peptides without resorting to specialized adjuvants. In this study we show that particulate polymeric Ag in the form of hybrid Ty virus-like particles carrying the V
Publikováno v:
Cancer research. 51(21)
The breast cancer-associated epitope (mammary serum antigen or MSA) defined by monoclonal antibody (Mab) 3E1.2 is a neuraminidase-sensitive carbohydrate expressed on MUC-1-encoded molecules. However, the reactivity of Mab 3E1.2 is also reduced by pro
Publikováno v:
BioTechniques. 8(4)