Zobrazeno 1 - 10
of 1 623
pro vyhledávání: '"G Schumacher"'
Autor:
V. N. Leukes, J. Hella, I. Sabi, M. Cossa, C. Khosa, B. Erkosar, C. Mangu, E. Siyame, B. Mtafya, A. Lwilla, S. Viegas, C. Madeira, A. Machiana, J. Ribeiro, A. L. Garcia-Basteiro, F. Riess, D. Elísio, M. Sasamalo, G. Mhalu, C. M. Denkinger, M. D. M. Castro, S. Bashir, S. G. Schumacher, E. Tagliani, A. Malhotra, D. Dowdy, C. Schacht, J. Buech, D. Nguenha, N. Ntinginya, M. Ruhwald, A. Penn-Nicholson, K. Kranzer, TB-CAPT Consortium
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background In 2020, the WHO-approved Molbio Truenat platform and MTB assays to detect Mycobacterium tuberculosis complex (MTB) and resistance to rifampicin directly on sputum specimens. This primary health care center-based trial in Mozambiq
Externí odkaz:
https://doaj.org/article/9e5a54ac3fab41c59c8f932721bcec7a
Autor:
Nicolas A. Menzies, Brian W. Allwood, Anna S. Dean, Pete J. Dodd, Rein M. G. J. Houben, Lyndon P. James, Gwenan M. Knight, Jamilah Meghji, Linh N. Nguyen, Andrea Rachow, Samuel G. Schumacher, Fuad Mirzayev, Ted Cohen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract In 2020, almost half a million individuals developed rifampicin-resistant tuberculosis (RR-TB). We estimated the global burden of RR-TB over the lifetime of affected individuals. We synthesized data on incidence, case detection, and treatmen
Externí odkaz:
https://doaj.org/article/67db4f0e99bd484ab56a1ea0cdfb46bf
Autor:
Jae Hyoung Lee, Tushar Garg, Jungsil Lee, Sean McGrath, Lori Rosman, Samuel G. Schumacher, Andrea Benedetti, Zhi Zhen Qin, Genevieve Gore, Madhukar Pai, Hojoon Sohn
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-23 (2022)
Abstract Background Countries with high TB burden have expanded access to molecular diagnostic tests. However, their impact on reducing delays in TB diagnosis and treatment has not been assessed. Our primary aim was to summarize the quantitative evid
Externí odkaz:
https://doaj.org/article/b480eb6746364176826a54b0025a1ce7
Autor:
Ioana D. Olaru, Mina Beliz Meier, Fuad Mirzayev, Nevena Prodanovic, Philip J. Kitchen, Samuel G. Schumacher, Claudia M. Denkinger
Publikováno v:
EClinicalMedicine, Vol 58, Iss , Pp 101938- (2023)
Summary: Background: There is a substantial overlap in the epidemiology of chronic hepatitis B (HBV), hepatitis C (HCV) and tuberculosis (TB) due to overlapping risk factors. Testing for viral hepatitis is not widely recommended for patients with TB.
Externí odkaz:
https://doaj.org/article/c67acfaedc6d40c7acebd036cfd520a5
Autor:
Alexandra J. Zimmer, Samuel G. Schumacher, Erik Södersten, Anna Mantsoki, Romain Wyss, David H. Persing, Sara Banderby, Linda Strömqvist Meuzelaar, Jacqueline Prieto, Devasena Gnanashanmugam, Purvesh Khatri, Stefano Ongarello, Morten Ruhwald, Claudia M. Denkinger
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract Objectives A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA sequencing platforms. The signature was recently translated by Cepheid i
Externí odkaz:
https://doaj.org/article/38d04284727c4d5c96a54ab1892ae1dc
Autor:
Yohhei Hamada, Adam Penn-Nicholson, Sriram Krishnan, Daniela Maria Cirillo, Alberto Matteelli, Romain Wyss, Claudia M. Denkinger, Molebogeng X. Rangaka, Morten Ruhwald, Samuel G. Schumacher
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104174- (2022)
Summary: Advances in discovery and validation of diagnostic, prognostic and treatment-monitoring transcriptomic signatures of tuberculosis (TB) disease could accelerate the goal to end TB. We conducted a review to evaluate whether mRNA transcriptomic
Externí odkaz:
https://doaj.org/article/5092bb5d625849719168eca6a6a1fdab
Autor:
Saskia Ricks, Emily A. Kendall, David W. Dowdy, Jilian A. Sacks, Samuel G. Schumacher, Nimalan Arinaminpathy
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Testing plays a critical role in treatment and prevention responses to the COVID-19 pandemic. Compared to nucleic acid tests (NATs), antigen-detection rapid diagnostic tests (Ag-RDTs) can be more accessible, but typically have low
Externí odkaz:
https://doaj.org/article/2eb6dc57206c4fb19a209ff79f7f859a
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT High-throughput centralized testing for tuberculosis (TB) and drug resistance is important, but comparative data are limited. In this retrospective cross-sectional study, participants were recruited from Johannesburg, South Africa, and Tbili
Externí odkaz:
https://doaj.org/article/06e0dd7e9a9244adb3beb6ed694c7baa
Autor:
J. Kevin Eckert, Paula C. Carder, Leslie A. Morgan, Ann Christine Frankowski, Erin G. Roth, Sheryl Zimmerman, Lynn Keimig, Robert L. Rubinstein, John G. Schumacher, Debra Dobbs, Tommy B. Piggee Jr, Leanne J. Clark
Assisted living is the fastest-growing alternative to skilled nursing care for frail older persons in the United States. The expectations, settings, and missions of these residences are varied, making it difficult for prospective residents and their
Autor:
Thomas H A Samuels, Romain Wyss, Stefano Ongarello, David A J Moore, Samuel G Schumacher, Claudia M Denkinger
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254002 (2021)
IntroductionA highly sensitive triage test that captures most symptomatic patients at increased likelihood of having pulmonary tuberculosis (PTB) would 'rule-out' lower-risk patients from expensive confirmatory testing. Although studies have assessed
Externí odkaz:
https://doaj.org/article/906a76910e944bc6b9e75f7db97389a5