Variability in Fetal Fraction Estimation: Comparing Fetal Fractions Reported by Noninvasive Prenatal Testing Providers Globally

Autor: Ellis C Becking, Jasper Linthorst, Simon Patton, Weronika Gutowska-Ding, Rebecca Goodall, Farrah Khawaja, Fiona Morgan, Zandra Deans, Lyn S Chitty, Mireille N Bekker, Peter G Scheffer, Erik A Sistermans

Publikováno v: Clinical Chemistry, 69(2), 160-167
Becking, E C, Linthorst, J, Patton, S, Gutowska-Ding, W, Goodall, R, Khawaja, F, Morgan, F, Deans, Z, Chitty, L S, Bekker, M N, Scheffer, P G & Sistermans, E A 2023, ' Variability in Fetal Fraction Estimation : Comparing Fetal Fractions Reported by Noninvasive Prenatal Testing Providers Globally ', Clinical Chemistry, vol. 69, no. 2, pp. 160-167 . https://doi.org/10.1093/clinchem/hvac207, https://doi.org/10.1093/clinchem/hvac207

Background Fetal fraction (FF) measurement is considered important for reliable noninvasive prenatal testing (NIPT). Using minimal FF threshold as a quality parameter is under debate. We evaluated the variability in reported FFs of individual samples

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8975efd7a85505fa8c02180ef7ce39a0
https://research.vumc.nl/en/publications/46b150cd-ce0e-4b4c-bcf8-f5480139a339

Association between low fetal fraction in cell‐free DNA testing and adverse pregnancy outcome: A systematic review

Autor: Lidewij Henneman, Peter G. Scheffer, Caroline J. Bax, Mireille N. Bekker, Ellis C. Becking, Marjan M. Weiss, Dick Oepkes, Erik A. Sistermans, Soetinah A. M. Wirjosoekarto

Publikováno v: Prenatal Diagnosis. 41:1287-1295

Objective: Low fetal fraction (LFF) in prenatal cell-free DNA (cfDNA) testing is an important cause of test failure and no-call results. LFF might reflect early abnormal placentation and therefore be associated with adverse pregnancy outcome. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2a67378d3865125eadee79db0b8ee9
https://doi.org/10.1002/pd.6028

Oxidative Stress in Complex Regional Pain Syndrome (CRPS): No Systemically Elevated Levels of Malondialdehyde, F2-Isoprostanes and 8OHdG in a Selected Sample of Patients

Autor: Wouter W. A. Zuurmond, Peter G. Scheffer, Jan Nouta, Roberto S. G. M. Perez, Sigrid G. L. Fischer

Publikováno v: International Journal of Molecular Sciences, Vol 14, Iss 4, Pp 7784-7794 (2013)

Exaggerated inflammation and oxidative stress are involved in the pathogenesis of Complex Regional Pain Syndrome (CRPS). However, studies assessing markers for oxidative stress in CRPS patients are limited. In this study, markers for lipid peroxidati

Externí odkaz: https://doaj.org/article/cbfe8bf2de144d7289fb36fa07a5f851

The subsurface sulfur system following hydraulic stimulation of unconventional hydrocarbon reservoirs: assessing anthropogenic influences on microbial sulfate reduction in the deep subsurface, Alberta

Autor: A W Kingston, O H Ardakani, G Scheffer, M Nightingale, C Hubert, B Meyer

Hydraulic fracturing is a reservoir stimulation technique that involves the injection of high-pressure fluids to enhance recovery from unconventional hydrocarbon reservoirs. Often this involves the injection of surface waters (along with additives su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4689b859b7e87a15d564fcb46fe7cc48
https://doi.org/10.4095/330712

Circulating oxidized LDL: determinants and association with brachial flow-mediated dilation

Autor: Leonard P. van der Zwan, Tom Teerlink, Jacqueline M. Dekker, Ronald M.A. Henry, Coen D.A. Stehouwer, Cornelis Jakobs, Robert J. Heine, Peter G. Scheffer

Publikováno v: Journal of Lipid Research, Vol 50, Iss 2, Pp 342-349 (2009)

Circulating oxidized LDL (oxLDL) levels are strongly correlated to LDL-cholesterol (LDL-c) and apolipoprotein-B100 (apoB100), making it difficult to disentangle their independent contributions to cardiovascular risk. We explored the determinants of o

Externí odkaz: https://doaj.org/article/b485f20ff866472a81ac0d733c90fd43