Zobrazeno 1 - 10
of 80
pro vyhledávání: '"G S Stein"'
Publikováno v:
Sarcoma, Vol 2011 (2011)
Osteosarcoma is an aggressive but ill-understood cancer of bone that predominantly affects adolescents. Its rarity and biological heterogeneity have limited studies of its molecular basis. In recent years, an important role has emerged for the RUNX2
Externí odkaz:
https://doaj.org/article/74bcab7dcdfb40fa90f8737ba35fdfd2
Publikováno v:
Chromosomal Nonhistone Proteins ISBN: 9781351070676
Chromosomal Nonhistone Proteins
Chromosomal Nonhistone Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e735e210100dd9cdfd8a9ca42dc7dde
https://doi.org/10.1201/9781351070676-5
https://doi.org/10.1201/9781351070676-5
Autor:
B Guo, P R Odgren, A J van Wijnen, T J Last, J Nickerson, S Penman, J B Lian, J L Stein, G S Stein
Publikováno v:
Proceedings of the National Academy of Sciences. 92:10526-10530
NMP-1 was initially identified as a nuclear matrix-associated DNA-binding factor that exhibits sequence-specific recognition for the site IV regulatory element of a histone H4 gene. This distal promoter domain is a nuclear matrix interaction site. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0588cdd4a9065a2b70dc4f2c92146f30
https://doi.org/10.1073/pnas.92.23.10526
https://doi.org/10.1073/pnas.92.23.10526
Autor:
P, Leboy, G, Grasso-Knight, M, D'Angelo, S W, Volk, J V, Lian, H, Drissi, G S, Stein, S L, Adams
Publikováno v:
The Journal of bone and joint surgery. American volume. (Pt 1)
Intracellular signaling triggered by bone morphogenetic proteins (BMPs) results in activated Smad complexes that regulate transcription of BMP-responsive genes. However, the low specificity of Smad binding to regulatory sequences implies that additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc68d655ae880442b218f85caac02c35
https://pubmed.ncbi.nlm.nih.gov/11263661
https://pubmed.ncbi.nlm.nih.gov/11263661
Publikováno v:
Journal of cellular biochemistry. 80(3)
The runt family transcription factor (AML-3/PEBP2alphaA1/Cbfa1/RUNX2) plays a crucial role in formation of the mineralized skeleton during embryogenesis and regulates maturation of the osteoblast phenotype. Because steroid hormones and growth factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe913b253f54852abe133a9faeec8837
https://pubmed.ncbi.nlm.nih.gov/11135373
https://pubmed.ncbi.nlm.nih.gov/11135373
Publikováno v:
Journal of cellular biochemistry. 80(1)
Contributing to bone-specific expression of the osteocalcin gene is the promoter element OC Box I (-99 to -76), which binds both Hox proteins and another nonhomeodomain factor (designated OCBP for osteocalcin-box binding protein) (Hoffmann et al. [19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3be20dd70a93c9457328f148a84079e2
https://pubmed.ncbi.nlm.nih.gov/11029763
https://pubmed.ncbi.nlm.nih.gov/11029763
Publikováno v:
Journal of cellular physiology. 185(2)
Transcriptional control at the G1/S-phase transition of the cell cycle requires functional interactions of multimeric promoter regulatory complexes that contain DNA binding proteins, transcriptional cofactors, and/or chromatin modifying enzymes. Tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a41084c86438b2f87295e11238d96245
https://pubmed.ncbi.nlm.nih.gov/11025449
https://pubmed.ncbi.nlm.nih.gov/11025449
Autor:
P B, Sigler, G S, Stein, A L, Boskey, N D, Jones, J, Kuriyan, W M, Miller, M L, Shuler, B C, Wang
Publikováno v:
Journal of cellular biochemistry. 79(4)
The recent National Research Council report, Future Biotechnology Research on the International Space Station, evaluates NASA's plans for research in cell science and protein crystal growth to be conducted on the International Space Station. This rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9fe1e056a0daee49a591fd743d05f6f5
https://pubmed.ncbi.nlm.nih.gov/10996856
https://pubmed.ncbi.nlm.nih.gov/10996856
Autor:
H, Drissi, Q, Luc, R, Shakoori, S, Chuva De Sousa Lopes, J Y, Choi, A, Terry, M, Hu, S, Jones, J C, Neil, J B, Lian, J L, Stein, A J, Van Wijnen, G S, Stein
Publikováno v:
Journal of cellular physiology. 184(3)
The runt related transcription factor CBFA1 (AML3/PEBP2alphaA/RUNX2) regulates expression of several bone- and cartilage-related genes and is required for bone formation in vivo. The gene regulatory mechanisms that control activation and repression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::104cecd1a18afd15a3527815e0f05409
https://pubmed.ncbi.nlm.nih.gov/10911365
https://pubmed.ncbi.nlm.nih.gov/10911365
Publikováno v:
Journal of cellular biochemistry. 79(1)
Promyelocytic leukemia (PML) nuclear bodies are important components of nuclear architecture that are functionally linked to aberrant gene expression and disease. To understand the mechanisms that modify subnuclear distribution and regulatory activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d645889ce1fbed42c2143b485e257e06
https://pubmed.ncbi.nlm.nih.gov/10906759
https://pubmed.ncbi.nlm.nih.gov/10906759