Zobrazeno 1 - 10
of 47
pro vyhledávání: '"G S Roth"'
Publikováno v:
Toxicological Sciences. 52:41-48
The effects of calorie restriction (CR) on life span, disease, and aging in physiological systems have been documented extensively in rodent models. However, whether CR has similar effects in longer-lived species more closely related to humans remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e58bada11ecbae9cca4048f5b43900d
https://doi.org/10.1093/toxsci/52.suppl_1.41
https://doi.org/10.1093/toxsci/52.suppl_1.41
Publikováno v:
Aging Clinical and Experimental Research. 9:304-308
Dietary restriction (DR) markedly extends mean and maximal life span, and retards the rate of biological aging in rodent models; however, it is unknown if these results occur in primate species. The purpose of the current study was to investigate sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1b929853cfb053f8937daadd80773e
https://doi.org/10.1007/bf03341833
https://doi.org/10.1007/bf03341833
Publikováno v:
Aging Clinical and Experimental Research. 5:349-356
We measured basal and dopamine-inhibited pituitary cell prolactin (PRL) release in vitro, and dopamine receptor binding in pituitary homogenates, from intact male and female Wistar rats of varying ages. During 48–72 hours in culture, the baseline s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d126b6eda99265c28885b927a477533d
https://doi.org/10.1007/bf03324186
https://doi.org/10.1007/bf03324186
Autor:
L K, STALKER, G S, ROTH
Publikováno v:
New York state journal of medicine. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::216ac077d70211b2539259aceca39c43
https://pubmed.ncbi.nlm.nih.gov/20988844
https://pubmed.ncbi.nlm.nih.gov/20988844
Publikováno v:
Aging Clinical and Experimental Research. 3:361-371
The present experiments were performed to determine whether the age-related loss of striatal D2 receptors could be localized to a kainic acid-sensitive neuronal population. This neurotoxin selectively destroys intrinsic neurons. Thus, if kainic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9662ab35a581fd8e4a77965b39994798
https://doi.org/10.1007/bf03324037
https://doi.org/10.1007/bf03324037
Publikováno v:
European journal of clinical nutrition. 54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8a6c45c72ef51f0799b534cefc6e86a
https://pubmed.ncbi.nlm.nih.gov/11041088
https://pubmed.ncbi.nlm.nih.gov/11041088
Publikováno v:
The journal of nutrition, healthaging. 3(2)
Caloric restriction (CR), undernutrition without malnutrition, remains the only experimental paradigm that has been shown consistently to extend lifespan and slow aging in short-lived species. Decades of research, mostly in laboratory rodents, have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1688bb3694bf2d1d1478b464fb0d9f70
https://pubmed.ncbi.nlm.nih.gov/10885801
https://pubmed.ncbi.nlm.nih.gov/10885801
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 52
The effects of calorie restriction (CR) on life span, disease, and aging in physiological systems have been documented extensively in rodent models. However, whether CR has similar effects in longer-lived species more closely related to humans remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e25bb60e71025907a61ecd7c53bbcb4c
https://pubmed.ncbi.nlm.nih.gov/10630589
https://pubmed.ncbi.nlm.nih.gov/10630589
Autor:
W R, Pendergrass, M A, Lane, N L, Bodkin, B C, Hansen, D K, Ingram, G S, Roth, L, Yi, H, Bin, N S, Wolf
Publikováno v:
Journal of cellular physiology. 180(1)
Caloric restriction (CR) is the most successful method of extending both median and maximal lifespans in rodents and other short-lived species. It is not yet clear whether this method of life extension will be successful in longer-lived species, poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ba51441f1a4facb4d121106179ad378
https://pubmed.ncbi.nlm.nih.gov/10362025
https://pubmed.ncbi.nlm.nih.gov/10362025
Publikováno v:
Journal of neuroscience research. 55(5)
We used adenoviral-mediated gene transfer of human amyloid precursor proteins (h-APPs) to evaluate the role of various h-APPs in causing neuronal cell death. We were able to infect PC12 cells with very high efficiency because approximately 90% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6942d0364dd6546ed24b96985bfd8418
https://pubmed.ncbi.nlm.nih.gov/10082085
https://pubmed.ncbi.nlm.nih.gov/10082085