Zobrazeno 1 - 10
of 40
pro vyhledávání: '"G S, Yost"'
Publikováno v:
Xenobiotica. 21:515-524
1. Male rabbits were given an i.p. injection of 15 mg/kg morphine and plasma concentrations of morphine and morphine-3-glucuronide (M3G) were simultaneously quantified by h.p.l.c. After 14 days of 10% ethanol in the rabbits' drinking water, a second
Autor:
G S, Yost
Publikováno v:
Advances in experimental medicine and biology. 500
Autor:
D L, Lanza, G S, Yost
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(7)
3-Methylindole (3 MI) is a selective pulmonary toxicant, and cytochrome P450 (P450) bioactivation of 3 MI, through hydroxylation, epoxidation, or dehydrogenation pathways, is a prerequisite for toxicity. CYP2F1 and CYP2F3 exclusively catalyze the deh
Publikováno v:
Journal of forensic sciences. 46(3)
Liquid chromatography-mass spectrometry was used to identify and quantify the predominant capsaicinoid analogues in extracts of fresh peppers, in oleoresin capsicum, and pepper sprays. The concentration of capsaicinoids in fresh peppers was variable.
Autor:
M, Ayroud, J D, Popp, M A, VanderKop, G S, Yost, D M, Haines, W, Majak, D, Karren, L J, Yanke, T A, McAllister
Publikováno v:
The Canadian veterinary journal = La revue veterinaire canadienne. 41(7)
Field data were collected over 2 consecutive years to characterize acute interstitial pneumonia (AIP) in feedyard cattle. Thirty-eight cattle with clinical symptoms of AIP were examined following emergency slaughter; 31 (all heifers) were confirmed t
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(10)
A study was conducted to investigate qualitative and quantitative aspects of the phase I metabolism of 3-methylindole (3MI) by porcine liver microsomes. Microsomal suspensions were prepared from the liver of 30 intact (uncastrated) male pigs. Metabol
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(7)
3-Methylindole (3MI) is a naturally occurring pulmonary toxin that requires metabolic activation. Previous studies have shown that 3MI-induced pneumotoxicity resulted from cytochrome P-450-catalyzed dehydrogenation of 3MI to an electrophilic methylen
Autor:
J D, Popp, T A, McAllister, J P, Kastelic, W, Majak, M, Ayroud, M A, VanderKop, D, Karren, G S, Yost, K J, Cheng
Publikováno v:
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 62(4)
The involvement of melengestrol acetate (MGA) in susceptibility to developing pulmonary edema and emphysema following oral administration of 3-methylindole (3MI) was investigated using 10 Suffolk ewes receiving 0 or 0.15 mg of MGA daily (n = 5). Bloo
Autor:
G S, Yost
Publikováno v:
Advances in experimental medicine and biology. 387
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(1)
Goats were jugularly infused with the pneumotoxin 3-methylindole (3MI; 15 mg/kg, 0.5 microCi/kg) dissolved in cremophor-EL to characterize the urinary metabolites of 3MI in a ruminant specie. Urine was collected for 36 hr after the beginning of a 2-h