Zobrazeno 1 - 10
of 22
pro vyhledávání: '"G S, Hageman"'
Autor:
M. A. Zouache, B. T. Richards, C. M. Pappas, R. A. Anstadt, J. Liu, T. Corsetti, S. Matthews, N. A. Seager, S. Schmitz-Valckenberg, M. Fleckenstein, W. C. Hubbard, J. Thomas, J. L. Hageman, B. L. Williams, G. S. Hageman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Dysregulation of the alternative pathway (AP) of the complement system is a significant contributor to age-related macular degeneration (AMD), a primary cause of irreversible vision loss worldwide. Here, we assess the contribution of the liv
Externí odkaz:
https://doaj.org/article/5509274071cb4770a0b493d6e99eb582
Autor:
K N, Alagramam, H, Yuan, M H, Kuehn, C L, Murcia, S, Wayne, C R, Srisailpathy, R B, Lowry, R, Knaus, L, Van Laer, F P, Bernier, S, Schwartz, C, Lee, C C, Morton, R F, Mullins, A, Ramesh, G, Van Camp, G S, Hageman, R P, Woychik, R J, Smith, G S, Hagemen
Publikováno v:
Human molecular genetics
We have determined the molecular basis for Usher syndrome type 1F (USH1F) in two families segregating for this type of syndromic deafness. By fluorescence in situ hybridization, we placed the human homolog of the mouse protocadherin Pcdh15 in the lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6524cf5f1965b23c42339cc0196a7945
https://hdl.handle.net/10067/358410151162165141
https://hdl.handle.net/10067/358410151162165141
Autor:
N L, Hawes, B, Chang, G S, Hageman, S, Nusinowitz, P M, Nishina, B S, Schneider, R S, Smith, T H, Roderick, M T, Davisson, J R, Heckenlively
Publikováno v:
Investigative ophthalmologyvisual science. 41(10)
To characterize the genetics and phenotype of a new mouse mutant with retinal degeneration, rd6, that is associated with extensive, scattered, small white retinal dots seen ophthalmoscopically.The phenotype was characterized using ophthalmoscopy, fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::471698085d4b73d0ba8dd84d8f0e4055
https://pubmed.ncbi.nlm.nih.gov/10967077
https://pubmed.ncbi.nlm.nih.gov/10967077
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 14(7)
Age-related macular degeneration (AMD), a blinding disorder that compromises central vision, is characterized by the accumulation of extracellular deposits, termed drusen, between the retinal pigmented epithelium and the choroid. Recent studies in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebeb5fba81f0c3c52db5d9d17d8bfe87
https://pubmed.ncbi.nlm.nih.gov/10783137
https://pubmed.ncbi.nlm.nih.gov/10783137
Autor:
J. Sebag, G. S. Hageman
Publikováno v:
European journal of ophthalmology. 10(1)
There are important similarities in molecular composition and structural organization of the interface between the vitreous and retina and that between the retina and retinal pigment epithelium. It is striking that the two most common causes of sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f59a71f7920884ce6bfbe648ece9855
https://pubmed.ncbi.nlm.nih.gov/10744197
https://pubmed.ncbi.nlm.nih.gov/10744197
Autor:
G S, Hageman, R F, Mullins
Publikováno v:
Molecular vision. 5
Age-related macular degeneration (AMD) is characterized in part by the deposition of extracellular deposits, including drusen, in the aging macula. A number of clinical studies have revealed a strong association between the number, size, and degree o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9679898098c5c810e99a3ea99f2f9d5d
https://pubmed.ncbi.nlm.nih.gov/10562652
https://pubmed.ncbi.nlm.nih.gov/10562652
Publikováno v:
Journal of neuroscience research. 42(1)
The distribution of transforming growth factor-beta (TGF-beta) was examined in the posterior segment of the monkey, human, and feline eye using antisera to TGF-beta 1, TGF-beta 2, or TGF-beta 3. A number of different antibodies, tissue processing met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853f8f14c724ee40517e5bfa9ee21572
https://pubmed.ncbi.nlm.nih.gov/8531227
https://pubmed.ncbi.nlm.nih.gov/8531227
Publikováno v:
Investigative ophthalmologyvisual science. 35(3)
To evaluate the retinal degeneration of the motor neuron degeneration (mnd) mouse, and to confirm its inheritance pattern and gene location.In screening the mnd/mnd mouse for ocular disease, a retinal degeneration was found that was evaluated by seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3348db29e87031877fdadab695bcc3cd
https://pubmed.ncbi.nlm.nih.gov/8125718
https://pubmed.ncbi.nlm.nih.gov/8125718
Publikováno v:
Investigative ophthalmologyvisual science. 35(2)
To determine factors that influence retinal adhesion in the primate and compare these with previous data from the rabbit.Retinal adhesiveness was studied in monkey eyes immediately after enucleation. The retina was peeled manually from the retinal pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e5c6f580e46c4806bc65e3134f7b9a8
https://pubmed.ncbi.nlm.nih.gov/8113025
https://pubmed.ncbi.nlm.nih.gov/8113025
Publikováno v:
Refractivecorneal surgery. 8(3)
We have recently developed a method for labeling and following the migration of keratocytes using the fluorescent dye, 4',6-diamidino-2-phenylindole (DAPI), which intercalates specifically into the adenine-thymine base pairs of deoxyribonucleic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4e75a92100467edf7c96afd64b649a9
https://pubmed.ncbi.nlm.nih.gov/1633143
https://pubmed.ncbi.nlm.nih.gov/1633143