Zobrazeno 1 - 10
of 29
pro vyhledávání: '"G S, Gray"'
Autor:
M G Levisetti, P A Padrid, G L Szot, N Mittal, S M Meehan, C L Wardrip, G S Gray, D S Bruce, J R Thistlethwaite, J A Bluestone
Publikováno v:
The Journal of Immunology. 159:5187-5191
Ag-specific T cell activation requires a CD28-mediated costimulatory interaction. This observation has suggested novel approaches to suppress donor-specific immunity, including the use of soluble CD28 antagonists, such as CTLA4Ig, which suppresses tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f2fbe3813c26f00c17b8fb42599fca
https://doi.org/10.4049/jimmunol.159.11.5187
https://doi.org/10.4049/jimmunol.159.11.5187
Publikováno v:
The Journal of Immunology. 157:3869-3875
Lethal toxic shock syndrome (TSS) results from the MHC class II presentation of bacterial superantigens, most commonly toxic shock syndrome-1 (TSST-1), to specific TCR Vbeta-bearing T cells. This superantigen-induced stimulation of whole T cell subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::523e85504ff46ff3a43db5278817ecfb
https://doi.org/10.4049/jimmunol.157.9.3869
https://doi.org/10.4049/jimmunol.157.9.3869
Publikováno v:
The Journal of Immunology. 155:1757-1766
Injection of parental lymphocytes into an unirradiated adult F1 host results in an acute GVH reaction characterized by immune deficiency, attack on host lymphohematopoietic tissues, and repopulation with donor-derived cells. All of these events resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaca9995d3b335ea0139f1e8b856de25
https://doi.org/10.4049/jimmunol.155.4.1757
https://doi.org/10.4049/jimmunol.155.4.1757
Publikováno v:
Diabetes. 44:816-823
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3afbe6ad4e3bdc67c5b0e3d9f24a180
https://doi.org/10.2337/diabetes.44.7.816
https://doi.org/10.2337/diabetes.44.7.816
Role of B7:CD28/CTLA-4 in the induction of chronic relapsing experimental allergic encephalomyelitis
Publikováno v:
The Journal of Immunology. 154:1481-1490
T cell activation requires both Ag/MHC recognition and costimulatory signals. The present studies were designed to test whether the loss of tolerance to myelin basic protein (MBP) requires costimulation by members of the B7 receptor family. CTLA-4Ig,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07bd2dac121550fbfadb1a871c2c30e3
https://doi.org/10.4049/jimmunol.154.3.1481
https://doi.org/10.4049/jimmunol.154.3.1481
Publikováno v:
The Journal of Immunology. 152:5723-5733
IL-4 has been shown to be involved in the early stages of B cell maturation. Changes induced by IL-4 include cell enlargement, increased viability, and increased MHC class II expression. However IL-4 alone does not induce B cell activation as defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f5ca45c39d2ecc4f89ddb73f84dad7
https://doi.org/10.4049/jimmunol.152.12.5723
https://doi.org/10.4049/jimmunol.152.12.5723
Publikováno v:
The Journal of Immunology. 152:5220-5225
The role of costimulation in Ag-induced responses of naive and differentiated IL-2 and IL-4-producing CD4+ T cells has been examined using cells from mice expressing a transgenic TCR specific for cytochrome c (81-104) + I-Ek. IL-2 secretion by naive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dbcec0883ef2d3beb6f01f9c8fcd6bf
https://doi.org/10.4049/jimmunol.152.11.5220
https://doi.org/10.4049/jimmunol.152.11.5220
Autor:
T Lindsten, K P Lee, E S Harris, B Petryniak, N Craighead, P J Reynolds, D B Lombard, G J Freeman, L M Nadler, G S Gray
Publikováno v:
The Journal of Immunology. 151:3489-3499
CTLA-4 is an adhesion receptor expressed on activated T cells. The amino acid sequence of CTLA-4 is related to CD28, and although the function of CTLA-4 remains unknown, it shares several features with CD28, including a common counter-receptor, B7, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe9550fb12bd254e4e412a7a4dd7953f
https://doi.org/10.4049/jimmunol.151.7.3489
https://doi.org/10.4049/jimmunol.151.7.3489
Autor:
A D, Kirk, D K, Tadaki, A, Celniker, D S, Batty, J D, Berning, J O, Colonna, F, Cruzata, E A, Elster, G S, Gray, R L, Kampen, N B, Patterson, P, Szklut, J, Swanson, H, Xu, D M, Harlan
Publikováno v:
Transplantation. 72(3)
CD80 and CD86 (also known as B7-1 and B7-2, respectively) are both ligands for the T cell costimulatory receptors CD28 and CD152. Both CD80 and CD86 mediate T cell costimulation, and as such, have been studied for their role in promoting allograft re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ab0edd2ed34a8790fb370f515446b41
https://pubmed.ncbi.nlm.nih.gov/11502964
https://pubmed.ncbi.nlm.nih.gov/11502964
Autor:
K, Sturmhoefel, K, Lee, G S, Gray, J, Thomas, R, Zollner, M, O'Toole, H, Swiniarski, A, Dorner, S F, Wolf
Publikováno v:
Cancer research. 59(19)
Fusion proteins consisting of the extracellular region of murine B7.1 or B7.2 and the Fc portion of murine IgG2a (B7-IgG) were evaluated for their ability to promote antitumor responses. Therapeutic administration of soluble B7-IgG in mice with estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::041bfc5adeeb3fa507d716371008a318
https://pubmed.ncbi.nlm.nih.gov/10519410
https://pubmed.ncbi.nlm.nih.gov/10519410