Zobrazeno 1 - 10
of 193
pro vyhledávání: '"G S, Gilkeson"'
Autor:
Saei, Amir A.1,2,3,4 (AUTHOR) amir.saei@ki.se, Lundin, Albin2 (AUTHOR), Lyu, Hezheng2 (AUTHOR), Gharibi, Hassan2 (AUTHOR), Luo, Huqiao5 (AUTHOR), Teppo, Jaakko2,6 (AUTHOR), Zhang, Xuepei2 (AUTHOR), Gaetani, Massimiliano2,7 (AUTHOR), Végvári, Ákos2 (AUTHOR), Holmdahl, Rikard5 (AUTHOR), Gygi, Steven P.1 (AUTHOR), Zubarev, Roman A.2,7 (AUTHOR) roman.zubarev@ki.se
Publikováno v:
Advanced Science. 10/16/2024, Vol. 11 Issue 38, p1-15. 15p.
Publikováno v:
The Journal of Immunology. 159:6083-6090
Anti-DNA induced in BALB/c mice by immunization with bacterial (Escherichia coli) DNA resemble spontaneous anti-DNA from lupus mice in V gene use and cross-reactivity with other nuclear Ags, but lack the high V(H) CDR3 arginine content seen in anti-D
Publikováno v:
The Journal of Immunology. 158:4500-4506
To elucidate the mechanism of Ag drive in the anti-DNA response, the Ab response to bacterial DNA has been analyzed in normal and autoimmune mice. Preautoimmune NZB/W mice immunized with Escherichia coli dsDNA produce Abs that resemble spontaneous au
Publikováno v:
The Journal of Immunology. 157:1297-1305
We recently produced a panel of seven glomerular-binding mAbs from a nephritic MRL-lpr mouse that bind to histones/nucleosomes (group I) or DNA (group II) adherent to glomerular basement membrane. To elucidate the molecular basis of their binding and
Publikováno v:
The Journal of Immunology. 151:1353-1364
Immunization of normal mice with bacterial DNA induces a significant anti-DNA response that includes antibodies resembling some lupus anti-DNA in their binding properties, although lacking specificity for mammalian dsDNA. To determine the structure o
Publikováno v:
The Journal of Immunology. 147:1759-1764
Although DNA is generally considered to be a poor immunogen, recent evidence suggests that DNA from various species differ in their immunologic activity and that bacterial DNA, unlike mammalian DNA, can induce significant antibody responses in mice.
Publikováno v:
The Journal of rheumatology. 28(12)
To examine the association between smoking and hair treatments (dyes, permanents) and risk of developing systemic lupus erythematosus (SLE).Patients (n = 265) diagnosed between January 1, 1995, and July 31, 1999, were recruited through 4 university b
Publikováno v:
Molecular medicine (Cambridge, Mass.). 6(9)
BACKGROUND: (MRL)-lpr/lpr mice spontaneously develop autoimmune disease characterized by arthritis and glomerulonephritis. Nitric oxide is postulated to play a role in the disease pathogenesis, as mice treated with the nitric oxide synthase inhibitor
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(8)
Microbial DNA has multiple immune effects including the capacity to induce polyclonal B cell activation and cytokine production in normal mice. We recently described the accelerated induction of anti-DNA Abs in NZB/NZW mice immunized with Escherichia
Publikováno v:
Arthritis and rheumatism. 41(10)