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pro vyhledávání: '"G S, Cottrell"'
Autor:
G S, Cottrell
Publikováno v:
British journal of pharmacology. 168(3)
The enzymatic activity of peptidases must be tightly regulated to prevent uncontrolled hydrolysis of peptide bonds, which could have devastating effects on biological systems. Peptidases are often generated as inactive propeptidases, secreted with en
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
Autor:
D P, Poole, C, Godfrey, F, Cattaruzza, G S, Cottrell, J G, Kirkland, J C, Pelayo, N W, Bunnett, C U, Corvera
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 22(7)
Bile acids (BAs) regulate cells by activating nuclear and membrane-bound receptors. G protein coupled bile acid receptor 1 (GpBAR1) is a membrane-bound G-protein-coupled receptor that can mediate the rapid, transcription-independent actions of BAs. A