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Autor:
Sathibalan Ponniah, Michael Papamichail, George E. Peoples, Diane F. Hale, Guy T. Clifton, JP Holmes, G Rellias, N. F. Pistamaltzian, Alan K. Sears, EA Mittendorf, Alexandros Ardavanis, Sonia A. Perez, Timothy J. Vreeland
Publikováno v:
Cancer Research. 71:P1-13
Introduction AE37 is the Ii-Key hybrid of the HER2−derived peptide AE36 (HER2:776–790). A phase I trial administering AE37 with the immunoadjuvant GM-CSF demonstrated the vaccine to be safe and capable of stimulating CD4+helper T-cells with HER2