Zobrazeno 1 - 10
of 937
pro vyhledávání: '"G Randolph"'
Autor:
Lorenza Bellusci, Gabrielle Grubbs, Shaimaa Sait, Lael M. Yonker, Adrienne G. Randolph, Tanya Novak, Takuma Kobayashi, Overcoming COVID−19 Investigators, Surender Khurana
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Emergence of highly transmissible Omicron subvariants led to increased SARS-CoV-2 infection and disease in children. However, minimal knowledge exists regarding the neutralization capacity against circulating Omicron BA.4/BA.5, BA.2.75, BQ.1
Externí odkaz:
https://doaj.org/article/0471c22309164850b84a03ed7c122ca3
Autor:
Noah G. Randolph-Flagg, Tucker Ely, Sanjoy M. Som, Everett L. Shock, Christopher R. German, Tori M. Hoehler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Several moons in the outer solar system host liquid water oceans. A key next step in assessing the habitability of these ocean worlds is to determine whether life’s elemental and energy requirements are also met. Phosphorus is required by
Externí odkaz:
https://doaj.org/article/d19bb98ebd614d9483dca45a63179850
Autor:
Zhengping Huang, Kailey E. Brodeur, Liang Chen, Du, Holly Wobma, Evan E. Hsu, Meng Liu, Joyce C. Chang, Margaret H. Chang, Janet Chou, Megan Day-Lewis, Fatma Dedeoglu, Olha Halyabar, James A. Lederer, Tianwang Li, Mindy S. Lo, Meiping Lu, Esra Meidan, Jane W. Newburger, Adrienne G. Randolph, Mary Beth Son, Robert P. Sundel, Maria L. Taylor, Huaxiang Wu, Qing Zhou, Scott W. Canna, Kevin Wei, Lauren A. Henderson, Peter A. Nigrovic, Pui Y. Lee
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
BACKGROUND Macrophage activation syndrome (MAS) is a life-threatening complication of Still’s disease (SD) characterized by overt immune cell activation and cytokine storm. We aimed to further understand the immunologic landscape of SD and MAS.METH
Externí odkaz:
https://doaj.org/article/81b3a17577a741b6be6230b306b10f60
Autor:
Aline B. Maddux, Cameron C. Young, Suden Kucukak, Laura D. Zambrano, Margaret M. Newhams, Caitlin K. Rollins, Natasha B. Halasa, Shira J. Gertz, Elizabeth H. Mack, Stephanie Schwartz, Michele Kong, Laura L. Loftis, Katherine Irby, Courtney M. Rowan, Keiko M. Tarquinio, Matt S. Zinter, Hillary Crandall, Natalie Z. Cvijanovich, Jennifer E. Schuster, Julie C. Fitzgerald, Mary A. Staat, Charlotte V. Hobbs, Ryan A. Nofziger, Steven Shein, Heidi Flori, Melissa L. Cullimore, Brandon M. Chatani, Emily R. Levy, Katri V. Typpo, Janet R. Hume, Angela P. Campbell, Adrienne G. Randolph, the Overcoming COVID-19 Investigators, Meghan Murdock, Heather Kelley, Candice Colston, Mary Glas Gaspers, Ronald C. Sanders, Emily Port, Rachel Mansour, Sara Shankman, Kaitlin Jones, Caitlin Rollins, Tanya Novak, Janet Chou, Mary Beth Son, Julia Clarke, Brooke Sens, Eve Listerud, Sabrina Chen, Kasey Stewart, Heidi R. Flori, Mary K. Dahmer, Supriya Behl, Noelle M. Drapeau, Lora Martin, Lacy Malloch, Maygan Martin, Kayla Patterson, Cameron Sanders, Kengo Inagaki, Sarah McGraw, Anita Dhanrajani, Abigail Kietzman, Shannon Hill, Russell J. McCulloh, Stephanie P. Schwartz, Tracie C. Walker, Mary Allen Staat, Rajashri Rasal, Ryan Burnett, Jenny Bush, Meena Golcha, Laura Stewart, Krow Ampofo, Manish M. Patel, Leora R. Feldstein, Mark W. Tenforde, Ashley M. Jackson, Angela Campbell
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
ObjectiveTo identify risk factors for persistent impairments after pediatric hospitalization for acute coronavirus disease 2019 (COVID-19) or multisystem inflammatory syndrome in children (MIS-C) during the SARS-CoV-2 pandemic.MethodsAcross 25 U.S. O
Externí odkaz:
https://doaj.org/article/1e2f7cbc16d047dbab50b8aeff084f5e
Autor:
Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Jonathan Abraham, Tanya Novak, Julian Hecker, Michael Cho, Surender Khurana, Lindsey R. Baden, Adrienne G. Randolph, Scott T. Weiss, Christoph Lange
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract As of June 2022, the GISAID database contains more than 11 million SARS-CoV-2 genomes, including several thousand nucleotide sequences for the most common variants such as delta or omicron. These SARS-CoV-2 strains have been collected from p
Externí odkaz:
https://doaj.org/article/428c807d66334f48a8d811a6960611da
Autor:
Michael Melgar, Eleanor G. Seaby, Andrew J. McArdle, Cameron C. Young, Angela P. Campbell, Nancy L. Murray, Manish M. Patel, Michael Levin, Adrienne G. Randolph, Mary Beth F. Son, BATS Consortium and the Overcoming COVID‐19 Investigators
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 9, Pp 804-810 (2022)
Objective Two cohort studies in patients with multisystem inflammatory syndrome in children (MIS‐C) demonstrated contrasting results regarding the benefit of initial immunomodulatory treatment with intravenous immunoglobulin (IVIG) alone versus IVI
Externí odkaz:
https://doaj.org/article/85275d3aef9f4457850dc98ab9fccae1
Autor:
Tanya Novak, Jeremy Chase Crawford, Georg Hahn, Mark W. Hall, Simone A. Thair, Margaret M. Newhams, Janet Chou, Peter M. Mourani, Keiko M. Tarquinio, Barry Markovitz, Laura L. Loftis, Scott L. Weiss, Renee Higgerson, Adam J. Schwarz, Neethi P. Pinto, Neal J. Thomas, Rainer G. Gedeit, Ronald C. Sanders, Sidharth Mahapatra, Bria M. Coates, Natalie Z. Cvijanovich, Kate G. Ackerman, David W. Tellez, Patrick McQuillen, Stephen C. Kurachek, Steven L. Shein, Christoph Lange, Paul G. Thomas, Adrienne G. Randolph
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundInfluenza virus is responsible for a large global burden of disease, especially in children. Multiple Organ Dysfunction Syndrome (MODS) is a life-threatening and fatal complication of severe influenza infection.MethodsWe measured RNA expres
Externí odkaz:
https://doaj.org/article/1b310ffd8aa249aa92844aef701a6cc3
Autor:
Juanjie Tang, Tanya Novak, Julian Hecker, Gabrielle Grubbs, Fatema Tuz Zahra, Lorenza Bellusci, Sara Pourhashemi, Janet Chou, Kristin Moffitt, Natasha B. Halasa, Stephanie P. Schwartz, Tracie C. Walker, Keiko M. Tarquinio, Matt S. Zinter, Mary A. Staat, Shira J. Gertz, Natalie Z. Cvijanovich, Jennifer E. Schuster, Laura L. Loftis, Bria M. Coates, Elizabeth H. Mack, Katherine Irby, Julie C. Fitzgerald, Courtney M. Rowan, Michele Kong, Heidi R. Flori, Aline B. Maddux, Steven L. Shein, Hillary Crandall, Janet R. Hume, Charlotte V. Hobbs, Adriana H. Tremoulet, Chisato Shimizu, Jane C. Burns, Sabrina R. Chen, Hye Kyung Moon, Christoph Lange, Adrienne G. Randolph, Surender Khurana
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The antibody response to the SARS-CoV-2 Omicron variant is not well studied in children. Here, the authors provide an age-stratified analysis of SARS-CoV-2 neutralizing capacity of sera from children with acute or convalescent COVID-19 as well as chi
Externí odkaz:
https://doaj.org/article/e95d32cb646c4ee9abe90f1a0721b0aa
Autor:
Mehdi Benamar, Qian Chen, Janet Chou, Amélie M. Julé, Rafik Boudra, Paola Contini, Elena Crestani, Peggy S. Lai, Muyun Wang, Jason Fong, Shira Rockwitz, Pui Lee, Tsz Man Fion Chan, Ekin Zeynep Altun, Eda Kepenekli, Elif Karakoc-Aydiner, Ahmet Ozen, Perran Boran, Fatih Aygun, Pinar Onal, Ayse Ayzit Kilinc Sakalli, Haluk Cokugras, Metin Yusuf Gelmez, Fatma Betul Oktelik, Esin Aktas Cetin, Yuelin Zhong, Maria Lucia Taylor, Katherine Irby, Natasha B. Halasa, Elizabeth H. Mack, Overcoming COVID-19 Investigators, Sara Signa, Ignazia Prigione, Marco Gattorno, Nicola Cotugno, Donato Amodio, Raif S. Geha, Mary Beth Son, Jane Newburger, Pankaj B. Agrawal, Stefano Volpi, Paolo Palma, Ayca Kiykim, Adrienne G. Randolph, Gunnur Deniz, Safa Baris, Raffaele De Palma, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Lauren A. Henderson, Talal A. Chatila
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Multisystem inflammatory syndrome in children (MIS-C) evolves in some pediatric patients following acute infection with SARS-CoV-2 by hitherto unknown mechanisms. Whereas acute-COVID-19 severity and outcomes were previously correlated with Notch4 exp
Externí odkaz:
https://doaj.org/article/a39c807bcee64be782682857c935eead
Autor:
Audrey Dionne, Kevin G. Friedman, Cameron C. Young, Margaret M. Newhams, Suden Kucukak, Ashley M. Jackson, Julie C. Fitzgerald, Laura S. Smallcomb, Sabrina Heidemann, Gwenn E. McLaughlin, Katherine Irby, Tamara T. Bradford, Steven M. Horwitz, Laura L. Loftis, Vijaya L. Soma, Courtney M. Rowan, Michele Kong, Natasha B. Halasa, Keiko M. Tarquinio, Adam J. Schwarz, Janet R. Hume, Shira J. Gertz, Katharine N. Clouser, Christopher L. Carroll, Kari Wellnitz, Melissa L. Cullimore, Sule Doymaz, Emily R. Levy, Katri V. Typpo, Amanda N. Lansell, Andrew D. Butler, Joseph D. Kuebler, Laura D. Zambrano, Angela P. Campbell, Manish M. Patel, Adrienne G. Randolph, Jane W. Newburger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 20 (2022)
Background Cardiac complications related to COVID‐19 in children and adolescents include ventricular dysfunction, myocarditis, coronary artery aneurysm, and bradyarrhythmias, but tachyarrhythmias are less understood. The goal of this study was to e
Externí odkaz:
https://doaj.org/article/fc489d960a7945f58b0805c631e6de55