Zobrazeno 1 - 10
of 36
pro vyhledávání: '"G R, Siggins"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
Ethanol alters N-methyl-D-aspartate (NMDA) and gamma-aminobutyric acid subtype A (GABA(A)) receptor-mediated neurotransmission. We have previously demonstrated that GABA(B) receptor blockade uncovers ethanol enhancement of GABA(A) responses in the hi
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(2)
The nucleus accumbens (NAcc) may be a key area in the rewarding effects of abused drugs. We previously showed that low ethanol concentrations decreased both N-methyl-D-aspartate (NMDA)-induced and kainate-induced currents in NAcc core neurons. To exp
Publikováno v:
Advances in experimental medicine and biology. 469
Autor:
I L, Campbell, T, Krucker, S, Steffensen, Y, Akwa, H C, Powell, T, Lane, D J, Carr, L H, Gold, S J, Henriksen, G R, Siggins
Publikováno v:
Brain research. 835(1)
Cytokines belonging to the type I interferon (e.g. interferon-alpha) family are important in the host response to infection and may have complex and broad ranging actions in the central nervous system (CNS) that may be beneficial or harmful. To bette
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(1)
We compared the effects of different metabotropic glutamate receptor (mGluR) agonists on pharmacologically isolated N-methyl-D-aspartate-excitatory postsynaptic currents (NMDA-EPSCs) in core nucleus accumbens neurons using conventional intracellular
Publikováno v:
Archives italiennes de biologie. 135(1)
In rat hippocampal slices, high intensity tetanic stimulation (two 1 s trains of 100 Hz separated by 20 s, 3-5X intensity of the test stimulus) of the Schaffer collateral-commissural (SCC) fibers induced a long-term depression (LTD) of the negative f
Autor:
L H, Gold, C J, Heyser, A J, Roberts, S J, Henriksen, S C, Steffensen, G R, Siggins, F P, Bellinger, C S, Chiang, H C, Powell, E, Masliah, I L, Campbell
Publikováno v:
Advances in experimental medicine and biology. 402
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(3)
The nucleus accumbens (NAcc) likely plays a role in the rewarding effects of several addictive drugs such as opiates and EtOH. We showed previously that low EtOH concentrations reduced glutamatergic excitatory postsynaptic potentials (EP-SPs) in NAcc
Publikováno v:
Sheng li xue bao : [Acta physiologica Sinica]. 45(6)
Behavioral studies indicate that nucleus accumbens (NAcc) is a key brain area for the rewarding effects of opiate and for opiate addiction. To find out the cellular correlates of opiate addiction, the effects of three kinds of opiate peptides on memb
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(3)
The nucleus accumbens septi (NAcc) is a key brain region in the rewarding effects of addictive drugs such as opiates and ethanol. We recently showed that opiate peptides reduced both excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs)