Výsledky vyhledávání - "G R, Langley"

Animals in science education—ethics and alternatives

Autor: G. R. Langley

Publikováno v: Journal of Biological Education. 25:274-279

Increasingly, moral objections are being voiced to the use or killing of animals for educational purposes, and students' opinions are reflecting this. An animal rights philosophy often underlies these objections, but many people are unaware of the lo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::037fb5209ce0ccd96c581ee6d295aea3
https://doi.org/10.1080/00219266.1991.9655225

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Outcome of Patients with Relapsed or Refractory Non-Hodgkin's Lymphoma Referred for Autologous Bone Marrow Transplantation

Autor: G R Langley, Joseph M. Brandwein, Burnell Mj, S B Sutcliffe, Armand Keating, A M Smith

Publikováno v: Leukemia & Lymphoma. 4:231-238

Fifty-one patients with relapsed or refractory intermediate- or high-grade non-Hodgkin's lymphoma were referred for autologous bone marrow transplantation (ABMT). The primary criterion for eligibility was sensitivity to conventional-dose salvage chem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5214fb46e032fd339e3a6ed0a47c9108
https://doi.org/10.3109/10428199109068071

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Demonstration of differences in drug resistance by direct testing of DNA excision repair activity following standard and liposomal daunorubicin exposure in normal paediatric marrow using high resolution CLSM

Autor: C L, Lannon, L M, Ball, A F, Pyesmany, M, Yhap, G R, Langley, D, van Velzen

Publikováno v: Advances in experimental medicine and biology. 457

High resolution Confocal Laser Scanning Microscopy (CLSM) may be applied to testing of drug resistance in vitro in clinical setting. Rapid analysis of DNA damage by precise quantitation of excised DNA in bone marrow samples exposed to potential treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::551616419e52d3d65e7dd37535b407c7
https://pubmed.ncbi.nlm.nih.gov/10500828

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Differential kinetics of drug resistance in human leukaemic cells measured by SCGE/CLSM

Autor: L M, Ball, C L, Lannon, G R, Langley, A F, Pyesmany, M, Yhap, D, van Velzen

Publikováno v: Advances in experimental medicine and biology. 457

New analogues of DNA directed chemotherapy moieties are available for comparative efficacy testing in human neoplastic disease. In addition to MTT testing direct assessment of DNA excision repair activity after direct exposure of marrow cells may pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a6feee8bdbc21bc5882b7537d97bc50
https://pubmed.ncbi.nlm.nih.gov/10500827

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Detection of a R173W mutation in the porphobilinogen deaminase gene in the Nova Scotian 'foreign Protestant' population with acute intermittent porphyria: a founder effect

Autor: M. Moss, V E Sangalang, W E Schreiber, S T Greene-Davis, J P Welch, O E Mann, P E Neumann, Gale I Dempsey, G R Langley, Bassam A. Nassar

Publikováno v: Clinical biochemistry. 30(8)

Objectives: Acute intermittent porphyria (AIP) is caused by mutations in the porphobilinogen deaminase (PBGD) gene that disrupt the function of the enzyme. Many mutations that lead to decreased PBGD activity have been described. An Arg to Trp substit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df4d35a238a86c1599317982be97212
https://pubmed.ncbi.nlm.nih.gov/9455613

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A regional autologous bone marrow transplant network: transfers to designated centers on the day after transplant

Autor: M, Crump, J M, Brandwein, A M, Smith, G R, Langley, M J, Burnell, L B, Huebsch, S J, Markman, K S, Robinson, D M, Sutton, H, Solh

Publikováno v: Bone marrow transplantation. 9(6)

Autologous bone marrow transplantation (ABMT) is becoming increasingly prevalent for treatment of advanced malignant disease. In order to increase the availability and utility of this therapy, we assessed the feasibility of transferring patients to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6abd68e0d75c8b43cfa981667b1b4e9a
https://pubmed.ncbi.nlm.nih.gov/1628129

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Immunoglobulin secretory function of B cells from untreated patients with chronic lymphocytic leukemia and hypogammaglobulinemia: role of T cells

Autor: L A, Fernandez, J M, MacSween, G R, Langley

Publikováno v: Blood. 62:767-774

The mechanism of the hypogammaglobulinemia in patients with chronic lymphocytic leukemia (CLL) was studied by determining the generation of specific immunoglobulin-secreting cells in response to mitogen and antigen stimulation in culture. Normal peri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a901aa332316a86c693f89a390088c47
https://doi.org/10.1182/blood.v62.4.767.bloodjournal624767

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