Zobrazeno 1 - 10
of 101
pro vyhledávání: '"G R, King"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 78:293-300
The present experiment evaluated the interactions between continuous cocaine dose, duration of administration, and duration of withdrawal on the induction of behavioral tolerance and changes in dopamine autoreceptor (DA) function. In the current expe
Publikováno v:
European Journal of Pharmacology. 394:97-101
Intermittent cocaine administration induces sensitization (reverse tolerance) to its behavioral effects. The mechanism(s) mediating sensitization is not clear, however, previous research has implicated 5-HT3 receptors in the expression of sensitizati
Publikováno v:
European Journal of Pharmacology. 364:79-87
The present experiment examined whether ondansetron, co-administered with continuous cocaine, would block the down regulation of accumbens 5-HT3 receptors. Rats were exposed to a 14-day pretreatment regimen that involved the continuous infusion of 40
Publikováno v:
Neuropsychopharmacology. 18:222-232
Using in vivo single-unit recording, we compared in rats the effects of continuous infusion and once-a-day injections of cocaine on the activity of single putative dopamine neurons in the substantia nigra and ventral tegmental area. After a 7-day wit
Publikováno v:
Pure and Applied Chemistry. 70:351-354
The structure elucidation of a number of metabolites isolated during biosynthetic studies on gibberellin-like fern antheridiogens from the Anemia genus has been undertaken by synthesising a series of reference samples from gibberellin A7. Two of the
Publikováno v:
Psychopharmacology. 130:159-165
The present experiment evaluated the ability of the 5-HT3 antagonist, ondansetron, administered during chronic cocaine administration, to block the development of sensitization and tolerance induced by the intermittent or continuous administration of
Publikováno v:
Neuroscience. 76:737-747
We have developed an antisense oligodeoxynucleotide to the dopamine transporter and used it to discriminate the behavioral properties of amphetamine and cocaine. In SK-N-MC cells permanently transfected with the dopamine transporter complementary DNA
Autor:
Jonathan C. Morris, Barbara Frey, Friedrich-Wilhelm Russkamp, Lewis N. Mander, Daniel Harry Rogers, G. R. King, Francis S. Roden, R. A. Bell
Publikováno v:
Pure and Applied Chemistry. 68:515-522
Several approaches to the total synthesis of the troponoid diterpene lactone 1 have been undertaken. The most successful approach to date has afforded secoharringtonolide 26. The intramolecular cyclopropanation reaction of an aryl ring by means of th
Publikováno v:
Psychopharmacology. 117:458-465
This experiment examined alterations in the ability of the highly selective 5-HT3 receptor agonist, 1-(m-chlorophenyl)-biguanide (mCPBG), to induce dopamine (DA) overflow in caudate brain slices obtained from rats withdrawn from continuous or intermi
Publikováno v:
Pharmacology Biochemistry and Behavior. 49:883-889
Research indicates that chronic daily cocaine injections produce sensitization to, while the chronic continuous infusion of cocaine produces tolerance to, its behavioral and neurochemical effects. The present experiments examined whether flupenthixol