Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G R, Jenkins"'
Publikováno v:
The British journal of dermatology. 162(2)
Acne is a common chronic inflammatory dermatosis of the pilosebaceous unit. It is characterized by seborrhoea, comedone formation and an inflammatory response consistent with defective cellular immunity to Propionibacterium acnes.The objective of thi
Autor:
G R, Jenkins, W H, Tolleson, D K, Newkirk, D W, Roberts, K L, Rowland, T, Saheki, K, Kobayashi, P C, Howard, W B, Melchior
Publikováno v:
Journal of biochemical and molecular toxicology. 14(6)
Fumonisin B1, a fungal mycotoxin that grows on corn and other agricultural products, alters sphingolipid metabolism by inhibiting ceramide synthase. The precise mechanism of fumonisin B1 toxicity has not been completely elucidated; however, a central
Autor:
Suzanne M. Morris, Lynda J. McGarrity, Paul C. Howard, William H. Tolleson, Letha H. Couch, William B. Melchior, Levan Muskhelishvili, Olen E. Domon, M Muskhelishvili, G. R. Jenkins
Publikováno v:
International journal of oncology. 14(5)
Fumonisin B1 stimulates apoptosis in a variety of cell types and tissues. We examined the role of sphingolipid changes in fumonisin B1-stimulated apoptosis. Sphinganine accumulated rapidly, sphingosine levels remained unchanged, and ceramides decreas
Publikováno v:
Blood. 89(7)
Plasmin, the primary fibrinolytic enzyme, has a broad substrate spectrum and participates in other biological processes dependent upon proteolytic activity. Consequently, plasmin activity is tightly regulated by plasminogen activators and protease in
Publikováno v:
Advances in experimental medicine and biology. 354
We have used a model system of normal HKc and HKc immortalized by transfection with HPV16 DNA (HKc/HPV16) to investigate the effect of RA on the growth of HKc/HPV16 and the expression of the HPV16 oncogenes E6 and E7. These studies found that HKc/HPV
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2(3)
Human papillomaviruses (HPVs), particularly types 16, 18, and 33, have recently been suggested as etiological agents for cervical neoplasia. However, few studies have explored this relationship among low-income minority women. This case-control study
Publikováno v:
Cancer research. 53(4)
We previously reported that human keratinocytes (HKc) immortalized by transfection with human papillomavirus type 16 DNA (HKc/HPV16) are more sensitive than normal HKc to growth inhibition by retinoic acid (RA), and that RA treatment of HKc/HPV16 inh
Publikováno v:
Cancer research. 52(1)
Human papillomavirus (HPV) type 16 (HPV16) is associated with a large percentage of cervical malignancies, and HPV16 DNA can immortalize human keratinocytes in vitro. The transforming ability of the virus resides primarily in the open reading frames
Publikováno v:
Journal of the Canadian Dental Association. 38(11)