Zobrazeno 1 - 10
of 10
pro vyhledávání: '"G R, Braslawsky"'
Publikováno v:
The Journal of Immunology. 150:5241-5251
Granulocyte-macrophage (GM)-CSF is an important hematopoietic cytokine that regulates proliferation and differentiation of macrophages, neutrophils, and eosinophils. In this study, we generated mAb to five synthetic peptides that correspond to region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3d40ebdd5d87f9ca08405bb97549cae
https://doi.org/10.4049/jimmunol.150.12.5241
https://doi.org/10.4049/jimmunol.150.12.5241
Autor:
P A, Trail, D, Willner, J, Knipe, A J, Henderson, S J, Lasch, M E, Zoeckler, M D, TrailSmith, T W, Doyle, H D, King, A M, Casazza, G R, Braslawsky, J, Brown, S J, Hofstead, R S, Greenfield, R A, Firestone, K, Mosure, K F, Kadow, M B, Yang, K E, Hellström, I, Hellström
Publikováno v:
Cancer research. 57(1)
The internalizing anti-Le(y) monoclonal antibody (MAb) BR64 was conjugated to the anticancer drug doxorubicin (DOX) using an acid-labile hydrazone bond to the DOX and either a disulfide or thioether bond to the MAb. The resulting disulfide (BR64-SS-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2f4c6c39908d2e124f01054ccecb092
https://pubmed.ncbi.nlm.nih.gov/8988048
https://pubmed.ncbi.nlm.nih.gov/8988048
Autor:
P A, Trail, D, Willner, S J, Lasch, A J, Henderson, R S, Greenfield, D, King, M E, Zoeckler, G R, Braslawsky
Publikováno v:
Cancer research. 52(20)
The anticarcinoma antibody BR64 was conjugated to a doxorubicin derivative, doxorubicin 13-[3-(2-pyridyldithio)propionyl]hydrazone, and the resulting conjugates (BR64-DOX) were evaluated for activity and immunological specificity in vitro and in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18e7b6be668738c2e2a95366d27a40ae
https://pubmed.ncbi.nlm.nih.gov/1382845
https://pubmed.ncbi.nlm.nih.gov/1382845
Publikováno v:
Cancer research. 50(20)
Adriamycin (ADM) was chemically coupled to two monoclonal antibodies (MAb) expressed on human B-cell lymphomas. Immunoconjugates were prepared by linking to the MAb an ADM derivative, Adriamycin 13-[3-(2-pyridyldithio)propionyl]hydrazone (ADM-HZN), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e4b21db7fa281b8caae2af36334b694
https://pubmed.ncbi.nlm.nih.gov/2208123
https://pubmed.ncbi.nlm.nih.gov/2208123
Autor:
R S, Greenfield, T, Kaneko, A, Daues, M A, Edson, K A, Fitzgerald, L J, Olech, J A, Grattan, G L, Spitalny, G R, Braslawsky
Publikováno v:
Cancer research. 50(20)
A novel method for linking Adriamycin (ADM) to monoclonal antibodies is described in which the 13-keto position of the anthracycline is used as the attachment site to the linker arm. A new ADM acylhydrazone derivative, Adriamycin 13-[3-(2-pyridyldith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3813fdc24b38433188d99ad8281524bb
https://pubmed.ncbi.nlm.nih.gov/2208122
https://pubmed.ncbi.nlm.nih.gov/2208122
Publikováno v:
Cytometry. 4:75-82
Flow cytometric histograms frequently consist of several components that show various degrees of overlap. For many types of analysis it is of great importance to decompose the original histogram into its components. To that purpose, we investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5b851c1390864f55dfd6a5a5d881af
https://doi.org/10.1002/cyto.990040111
https://doi.org/10.1002/cyto.990040111
Publikováno v:
Progress in nucleic acid research and molecular biology. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::157df00bc325001febd533614d757c97
https://pubmed.ncbi.nlm.nih.gov/6665171
https://pubmed.ncbi.nlm.nih.gov/6665171
Publisher Summary Explant cultures of F-344 rat tracheas exposed in vivo or in vitro to chemical carcinogens form established cell lines, whereas nonexposed tracheal explants do not. Many of these carcinogen-altered cell lines are not capable of form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed12a628fbe50651b67368c50023f5e1
https://doi.org/10.1016/s0079-6603(08)60457-2
https://doi.org/10.1016/s0079-6603(08)60457-2
Publikováno v:
Advances in experimental medicine and biology. 66
In this study we demonstrated that cells lodging in tumors have the capacity to fix antibody or immune complexes in vivo and in vitro. Although some of the fixation is probably by host, at least in one system studied, tumor cells, per se, were found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b5a97bf4f97e951d5a0a55709f93811
https://pubmed.ncbi.nlm.nih.gov/773125
https://pubmed.ncbi.nlm.nih.gov/773125
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 116(6)
In this paper we present evidence that antibodies unrelated to the tumor cell can comprise part of the in vivo Ig surface coat of cells derived from the non-lymphoid murine tumor, TA3/St. This was shown by incubating TA3 cells originating from other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e0a18058272acdec01eb34718cf4c12
https://pubmed.ncbi.nlm.nih.gov/1270806
https://pubmed.ncbi.nlm.nih.gov/1270806