Zobrazeno 1 - 3
of 3
pro vyhledávání: '"G R, Abecasis"'
Common genetic variants identify targets for COVID-19 and individuals at high risk of severe disease
Autor:
J E, Horowitz, J A, Kosmicki, A, Damask, D, Sharma, G H L, Roberts, A E, Justice, N, Banerjee, M V, Coignet, A, Yadav, J B, Leader, A, Marcketta, D S, Park, R, Lanche, E, Maxwell, S C, Knight, X, Bai, H, Guturu, D, Sun, A, Baltzell, F S P, Kury, J D, Backman, A R, Girshick, C, O'Dushlaine, S R, McCurdy, R, Partha, A J, Mansfield, D A, Turissini, A H, Li, M, Zhang, J, Mbatchou, K, Watanabe, L, Gurski, S E, McCarthy, H M, Kang, L, Dobbyn, E, Stahl, A, Verma, G, Sirugo, M D, Ritchie, M, Jones, S, Balasubramanian, K, Siminovitch, W J, Salerno, A R, Shuldiner, D J, Rader, T, Mirshahi, A E, Locke, J, Marchini, J D, Overton, D J, Carey, L, Habegger, M N, Cantor, K A, Rand, E L, Hong, J G, Reid, C A, Ball, A, Baras, G R, Abecasis, M A, Ferreira
Publikováno v:
medRxiv
The need to identify and effectively treat COVID-19 cases at highest risk for severe disease remains critical. We identified five common genetic loci (two novel) that modulate both COVID-19 susceptibility and severity, implicating TMPRSS2, IFNAR2, CC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0280def6ca331ba9b219c4a4db248c7d
https://europepmc.org/articles/PMC7899471/
https://europepmc.org/articles/PMC7899471/
Publikováno v:
Annals of Human Genetics. 66:211-221
Autor:
L R, Cardon, G R, Abecasis
Publikováno v:
Behavior genetics. 30(3)
Identifying etiological variants for multifactorial traits by allelic association holds promise when many markers are available in close proximity. However, evidence for or against association at any particular marker does not provide any direct info