Zobrazeno 1 - 10
of 37
pro vyhledávání: '"G Protein-Coupled Receptor Gene"'
Autor:
Guanghui Wang, Huaijian Xu, Chaofeng Hao, Cong Jiang, Chen Gong, Jin-Rong Xu, Zeyi Wang, Chanjing Feng, Shulin Cao, Huiquan Liu, Mingyu Ding, Jie Liang, Qinhu Wang
Publikováno v:
Nature Microbiology. 4:1582-1591
The cAMP-PKA and MAP kinase pathways are essential for plant infection in the wheat head blight fungus Fusarium graminearum. To identify upstream receptors of these well-conserved signalling pathways, we systematically characterized the 105 G-protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ccb42cddc8535bf77c79da1f7fb6a3
https://doi.org/10.1038/s41564-019-0468-8
https://doi.org/10.1038/s41564-019-0468-8
Publikováno v:
Molecular and biochemical parasitology. 222
The diversity and uniqueness of nematode heterotrimeric G-protein-coupled receptors (GPCRs) provides impetus for identifying ligands that can be used as therapeutics for treating diseases caused by parasitic nematode infections. In human medicine, GP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e29ce94795f99c083c80f1b4281a8a0
https://pubmed.ncbi.nlm.nih.gov/29625152
https://pubmed.ncbi.nlm.nih.gov/29625152
Publikováno v:
Clinical endocrinology. 88(3)
The human genome encodes more than 700 G-protein-coupled receptors (GPCRs), many of which are involved in hormone secretion. To date, more than 100 gain-of-function (activating) mutations in at least ten genes for GPCRs, in addition to several loss-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c953b5ee3496af73b07387b94360fc5
https://pubmed.ncbi.nlm.nih.gov/29029377
https://pubmed.ncbi.nlm.nih.gov/29029377
Autor:
Steven R. Ahrendt, Andrew H. Barsoum, Alexander V. Michkov, Taffani H. Lai, Ilva E. Cabrera, Wan-Ching Chen, Itallia V. Pacentine, Stephanie Kim, Carlos Rojas Torres, Katherine A. Borkovich, Jackie Cao, Jacqueline A. Servin, Sho M. Kitada, Cristin Malekyan, Toua R. Moua, Liza M. Davidson, Andrew Lim, Liande Li, Ronald Castillo, Nayeli Guerrero, Ashley Mach, Alaina Yamamoto, Svetlana Krystofova, Alexander J. Carrillo, Alex Dinkchian
Publikováno v:
G3 (Bethesda, Md.), vol 5, iss 12
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
G protein−coupled receptors (GPCRs) regulate facets of growth, development, and environmental sensing in eukaryotes, including filamentous fungi. The largest predicted GPCR class in these organisms is the Pth11-related, with members similar to a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f472e48e5b05206da0e7e519210af969
https://escholarship.org/uc/item/1pt9x54t
https://escholarship.org/uc/item/1pt9x54t
Autor:
Yann Gibert, Gerrit Begemann, Perrin C. White, Axel Meyer, D. Randy McMillan, Kathleen M. Kayes-Wandover
Publikováno v:
Gene. 353:200-206
Very Large G-protein coupled Receptor-1 (VLGR1/Mass1/USH2C) is the largest known cell surface protein in vertebrates. Mutations in VLGR1 are associated with audiogenic epilepsy in mice and Usher syndrome (sensorineural deafness and retinitis pigmento
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc94e9ff7db828b8fa6f361bced0af3c
https://doi.org/10.1016/j.gene.2005.05.015
https://doi.org/10.1016/j.gene.2005.05.015
Autor:
Yuka Imamura Kawasawa, David P. Hill, Masashi Yanagisawa, Hidemasa Bono, Louise M McKenzie, Gsl Members
Publikováno v:
Genome Research. 13:1466-1477
G protein-coupled receptors (GPCRs) comprise the largest family of receptor proteins in mammals and play important roles in many physiological and pathological processes. Gene expression of GPCRs is temporally and spatially regulated, and many splici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4b1e24b0a593f98483533c730a5fcd
https://doi.org/10.1101/gr.1087603
https://doi.org/10.1101/gr.1087603
Autor:
Paul A. Insel, Andria Lee, David M. Weiner, Hans H. Schiffer, Nicholas J. Schork, Mark R. Brann, Brinda K. Rana
Publikováno v:
Genomics. 81:245-248
The G-protein-coupled receptor (GPCR) superfamily is one of the largest classes of proteins in mammalian genomes. GPCRs mediate diverse physiological functions and are the targets of >50% of all clinical drugs. The sequencing of the human genome and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a2e945162f5b88603ab0d4e1c2e221
https://doi.org/10.1016/s0888-7543(03)00009-0
https://doi.org/10.1016/s0888-7543(03)00009-0
Autor:
Takahito Nishikata, Kazuma Etani
Publikováno v:
Development Genes and Evolution. 212:447-451
We have cloned a newly identified gene, designated CiNut, C iona i ntestinalis neural-tube-specific gene. CiNut shows weak similarity to known neural receptors such as adrenergic receptors. Moreover, seven transmembrane domains are predicted based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694324015d932c40ed4453be68ff41e8
https://doi.org/10.1007/s00427-002-0260-1
https://doi.org/10.1007/s00427-002-0260-1
Autor:
Grant R. Sutherland, Nancy A. Jenkins, Karen Darby, Joanna Crawford, Debra J. Gilbert, Helen J. Eyre, Neal G. Copeland, Herbert Herzog, Marjorie Liu, Rachel M. C. Parker
Publikováno v:
Genomics. 55:296-305
A novel gene product, GPR56, with homology to the seven transmembrane-domain receptor superfamily, has been cloned by PCR amplification using degenerate oligonucleotide primers and subsequent screening of a human heart cDNA library. The isolated 2.8-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e513c42fc72f0c7aa63f383eed373f1e
https://doi.org/10.1006/geno.1998.5644
https://doi.org/10.1006/geno.1998.5644
Autor:
Brian F. O'Dowd, Marek Sawzdargo, Henry H.Q. Heng, Tuan V. Nguyen, Dennis Lee, Regina Cheng, Susan R. George, Kevin R. Lynch
Publikováno v:
Molecular Brain Research. 64:193-198
The G protein-coupled receptor (GPCR) family share a structural motif of seven transmembrane segments with large numbers of conserved residues in those regions. Here, we report the identification and cloning of two novel human intronless GPCR genes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ffa242004fc175dc1be864397d8f5d
https://doi.org/10.1016/s0169-328x(98)00277-0
https://doi.org/10.1016/s0169-328x(98)00277-0