Zobrazeno 1 - 10
of 175
pro vyhledávání: '"G Pommier"'
Publikováno v:
RSC Med Chem
Protein–protein interactions (PPIs) are large, often featureless domains whose modulations by small-molecules are challenging. Whilst there are some notable successes, such as the BCL-2 inhibitor venetoclax, the requirement for larger ligands to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d1b61568607e6177e7cebcca6b4b67
https://pubmed.ncbi.nlm.nih.gov/36092144
https://pubmed.ncbi.nlm.nih.gov/36092144
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Thrombosis Research. 119:441-446
Clinical manifestations of the antiphospholipid antibody syndrome (APS) have been recently related to the presence of phosphatidylethanolamine antibodies (aPE). However, it is well known that some molecules such as cryoglobulins, immunoglobulins that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161a70b13a71a10354991818a166f646
https://doi.org/10.1016/j.thromres.2006.04.006
https://doi.org/10.1016/j.thromres.2006.04.006
Autor:
Yves G. Pommier, Carolyn A. Felix, Ian A. Blair, Eric F. Rappaport, Maureen D. Megonigal, Timothy R. Rebbeck, Brian D. Lovett, Donald A. Burden, Dirk Strumberg, Shaokun Pang, Neil Osheroff
Publikováno v:
Biochemistry. 40:1159-1170
Chromosomal breakage resulting from stabilization of DNA topoisomerase II covalent complexes by epipodophyllotoxins may play a role in the genesis of leukemia-associated MLL gene translocations. We investigated whether etoposide catechol and quinone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4a74530c034a3d98f6604f360f07c4
https://doi.org/10.1021/bi002361x
https://doi.org/10.1021/bi002361x
Autor:
Hiremagalur N. Jayaram, Thomas Szekeres, Joel A. Yalowitz, Yves G. Pommier, Kamran Gharehbaghi, Monika Fritzer-Szekeres
Publikováno v:
Life Sciences. 68:1-11
Cyclopentenylcytosine (CPEC) is cytotoxic to HT-29 cells in vitro and in vivo. Treatment with CPEC resulted in sensitizing HT-29 cells to cisplatin (CDDP), as evidenced by synergistic cytotoxicity. CPEC exhibits potent cytotoxicity to HT-29 cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3cd92ec967d3c8986afd00f0559823
https://doi.org/10.1016/s0024-3205(00)00914-0
https://doi.org/10.1016/s0024-3205(00)00914-0
Publikováno v:
APOPTOSIS. 4:47-58
Paclitaxel and docetaxel are potent anti-microtubule and antimitotic agents that induce apoptosis in bone marrow-derived cells and epithelial cells. This study examined apoptosis induced by anti-microtubule agents in the neuroblastoma SK-N-SH cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8398c9386ac2eacee108ccedff4cb159
https://doi.org/10.1023/a:1009682116158
https://doi.org/10.1023/a:1009682116158
Autor:
M Remacle-Bonnet, F Garrouste, R Guidicelli, MA Christofilis, P Fuentes, C Atlan-Gepner, B. Vialettes, G Pommier
Publikováno v:
European Journal of Endocrinology. 139:317-322
Extrapancreatic tumor hypoglycemia (EPTH) is associated with increased amounts of high-molecular-weight precursor forms of insulin-like growth factor (IGF)-II ('big-IGF-II') that have a primary role in the pathophysiology of hypoglycemia. In the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ccafac75c913a8628b52f787e12379
https://doi.org/10.1530/eje.0.1390317
https://doi.org/10.1530/eje.0.1390317
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5adcb7a74533d011f4c326899366999a
https://doi.org/10.1002/chin.200614203
https://doi.org/10.1002/chin.200614203