Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis

Autor: Subash Raj Susai, Colm Healy, David Mongan, Meike Heurich, Jonah F. Byrne, Mary Cannon, Gerard Cagney, Kieran Wynne, Connie Markulev, Miriam R. Schäfer, Maximus Berger, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Rebekah Street, Andrew Thompson, Alison Ruth Yung, Barnaby Nelson, Patrick D. McGorry, Melanie Föcking, G. Paul Amminger, David Cotter

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) in early psychosis. The present study investigates the molecular mechanism of omega-3 PUFA-associated therapeutic effects in clinical high-risk

Externí odkaz: https://doaj.org/article/ef015f3560c34a10bba31b92235544a1

Youth Depression Alleviation with Anti-inflammatory Agents (YoDA-A): a randomised clinical trial of rosuvastatin and aspirin

Autor: Michael Berk, Mohammadreza Mohebbi, Olivia M. Dean, Sue M. Cotton, Andrew M. Chanen, Seetal Dodd, Aswin Ratheesh, G. Paul Amminger, Mark Phelan, Amber Weller, Andrew Mackinnon, Francesco Giorlando, Shelley Baird, Lisa Incerti, Rachel E. Brodie, Natalie O. Ferguson, Simon Rice, Miriam R. Schäfer, Edward Mullen, Sarah Hetrick, Melissa Kerr, Susy M. Harrigan, Amelia L. Quinn, Catherine Mazza, Patrick McGorry, Christopher G. Davey

Publikováno v: BMC Medicine, Vol 18, Iss 1, Pp 1-12 (2020)

Abstract Background Inflammation contributes to the pathophysiology of major depressive disorder (MDD), and anti-inflammatory strategies might therefore have therapeutic potential. This trial aimed to determine whether adjunctive aspirin or rosuvasta

Externí odkaz: https://doaj.org/article/e324650ad0254ef1909b710205791da0

Corrigendum: Relationship Between Polyunsaturated Fatty Acids and Psychopathology in the NEURAPRO Clinical Trial

Autor: Maximus Berger, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R. Schäfer, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Todd W. Mitchell, Barbara J. Meyer, Andrew Thompson, Alison Ruth Yung, Patrick D. McGorry, G. Paul Amminger

Publikováno v: Frontiers in Psychiatry, Vol 11 (2020)

Externí odkaz: https://doaj.org/article/40f78615095149b8b106023c773e4673

Relationship Between Polyunsaturated Fatty Acids and Psychopathology in the NEURAPRO Clinical Trial

Autor: Maximus Berger, Barnaby Nelson, Connie Markulev, Hok Pan Yuen, Miriam R. Schäfer, Nilufar Mossaheb, Monika Schlögelhofer, Stefan Smesny, Ian B. Hickie, Gregor E. Berger, Eric Y. H. Chen, Lieuwe de Haan, Dorien H. Nieman, Merete Nordentoft, Anita Riecher-Rössler, Swapna Verma, Todd W. Mitchell, Barbara J. Meyer, Andrew Thompson, Alison Ruth Yung, Patrick D. McGorry, G. Paul Amminger

Publikováno v: Frontiers in Psychiatry, Vol 10 (2019)

BackgroundDeficiencies in membrane polyunsaturated fatty acids (PUFA) such as omega-3 (n-3) fatty acids are thought to contribute to the pathophysiological processes underlying psychotic disorders. Emerging evidence suggests that the levels of PUFA a

Externí odkaz: https://doaj.org/article/df0c2ce4a5e24a5aa8a784f6408c8c23

Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis

Autor: Nadine C van der Burg, Philip McGuire, Birte Glenthøj, Stephan Ruhrmann, Jim van Os, Bart P. F. Rutten, Neus Barrantes-Vidal, Patrick D. McGorry, Frederike Schirmbeck, Gabriele Sachs, Rodrigo A. Bressan, Barnaby Nelson, Marie-Odile Krebs, Jentien M Vermeulen, Anita Riecher-Rössler, G. Paul Amminger, Matthijs Blankers, Lucia Valmaggia, Mark van der Gaag, Christos Pantelis, Paolo Fusar-Poli, Merete Nordentoft, Lieuwe de Haan, Matthew J. Kempton

Publikováno v: 2021, ' Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis ', Schizophrenia Bulletin . https://doi.org/10.1093/schbul/sbab088
Schizophrenia bulletin, 48(1), 100-110. Oxford University Press
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Schirmbeck, F, van der Burg, N C, Blankers, M, Vermeulen, J M, McGuire, P, Valmaggia, L R, Kempton, M J, van der Gaag, M, Riecher-Rössler, A, Bressan, R A, Barrantes-Vidal, N, Nelson, B, Amminger, G P, McGorry, P, Pantelis, C, Krebs, M O, Ruhrmann, S, Sachs, G, Rutten, B P F, van Os, J, Nordentoft, M, Glenthøj, B, Fusar-Poli, P, de Haan, L & EU-GEI High Risk Study Group Authors 2022, ' Impact of Comorbid Affective Disorders on Longitudinal Clinical Outcomes in Individuals at Ultra-high Risk for Psychosis ', Schizophrenia Bulletin, vol. 48, no. 1, pp. 100-110 . https://doi.org/10.1093/schbul/sbab088
Schizophrenia Bulletin
Schizophrenia Bulletin, Oxford University Press (OUP), 2021, pp.sbab088. ⟨10.1093/schbul/sbab088⟩
Schizophrenia Bulletin, 2021, pp.sbab088. ⟨10.1093/schbul/sbab088⟩
Schizophrenia Bulletin, 48(1), 100-110. Oxford University Press

Introduction Diagnoses of anxiety and/or depression are common in subjects at Ultra-High Risk for Psychosis (UHR) and associated with extensive functional impairment. Less is known about the impact of affective comorbidities on the prospective course

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea3642f83daee1e196c2300a0651d9b
https://doi.org/10.1093/schbul/sbab088