A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal Disease.

Autor: Emmadi M; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany., Khan N; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany., Lykke L; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany., Reppe K; Department of Infectious Diseases and Pulmonary Medicine, Charité-Universitätsmedizin Berlin , Charitéplatz 1, 10117 Berlin, Germany., G Parameswarappa S; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany., Lisboa MP; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany., Wienhold SM; Department of Infectious Diseases and Pulmonary Medicine, Charité-Universitätsmedizin Berlin , Charitéplatz 1, 10117 Berlin, Germany., Witzenrath M; Department of Infectious Diseases and Pulmonary Medicine, Charité-Universitätsmedizin Berlin , Charitéplatz 1, 10117 Berlin, Germany., Pereira CL; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany., Seeberger PH; Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces , D-14424 Potsdam, Germany.; Department of Chemistry and Biochemistry, Freie Universität Berlin , Arnimallee 22, D-14195 Berlin, Germany.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2017 Oct 18; Vol. 139 (41), pp. 14783-14791. Date of Electronic Publication: 2017 Oct 04.