Zobrazeno 1 - 10
of 26
pro vyhledávání: '"G P Sandilands"'
Publikováno v:
Clinical and Experimental Immunology. 162:516-527
Summary The precise biological mechanisms that caused the TGN1412 clinical trial tragedy (also known as ‘The Elephant Man Clinical Trial’) in March 2006 remain a mystery to this day. It is assumed widely that the drug used in this trial (TGN1412)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989e066404cee1030a1c98c04a5ce48f
https://doi.org/10.1111/j.1365-2249.2010.04264.x
https://doi.org/10.1111/j.1365-2249.2010.04264.x
Publikováno v:
Immunology. 119:562-571
We have previously shown that normal human peripheral blood polymorphonuclear neutrophils (PMNs) contain cytoplasmic ‘stores’ of three key molecules normally associated with antigen presentation and T-cell costimulation, i.e. major histocompatibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9110e1f0856b51575b0d0f53acdeab7
https://doi.org/10.1111/j.1365-2567.2006.02471.x
https://doi.org/10.1111/j.1365-2567.2006.02471.x
Publikováno v:
Immunology. 114:354-368
Recent studies suggest that neutrophils may play a role in antigen presentation. In support of this hypothesis it has been shown that these cells appear to contain cytoplasmic stores of molecules required for this function, i.e. major histocompatibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9353b7597d23173ea939e3a97e4f6a63
https://doi.org/10.1111/j.1365-2567.2004.02114.x
https://doi.org/10.1111/j.1365-2567.2004.02114.x
Autor:
Elizabeth Loudon, Roderick K. Ferrier, Carol Campbell, G. P. Sandilands, Martina E. Rodie, Andrew G. Marsh, Anna Gondowidjojo, Birgit Hauffe
Publikováno v:
Immunology. 108:329-337
Polymorphonuclear neutrophils (PMNs) are capable of synthesizing various pro-inflammatory cytokines which may indirectly influence specific immune responses. PMNs may also have the capacity to present foreign peptides to helper T cells (Th cells). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0d2a891052059c9d428965230f07f4
https://doi.org/10.1046/j.1365-2567.2003.01591.x
https://doi.org/10.1046/j.1365-2567.2003.01591.x
Autor:
I. Downie, R. N. M. Macsween, G. P. Sandilands, A. J. Russell, S. A. Macpherson, E. R. Burnett
Publikováno v:
Immunology. 91:204-211
Receptors for the Fc region of immunoglobulin G (IgG) (Fc gamma Rs) exist in three main forms: membrane bound, soluble and cytoplasmic. The function of cytoplasmic Fc gamma Rs is poorly understood. We have previously demonstrated cytoplasmic Fc gamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb46597676ad0ea5532e4e177ee9f39c
https://doi.org/10.1046/j.1365-2567.1997.00241.x
https://doi.org/10.1046/j.1365-2567.1997.00241.x
Autor:
S. A. Macpherson, E. R. Burnett, G. P. Sandilands, I. Downie, R. N. M. Macsween, I. A. R. More
Publikováno v:
Immunology. 90:427-434
We have recently described a cytoplasmic from of CD32 (Fc gamma RII) within the vast majority of normal human peripheral blood lymphocytes (PBL) including T cells. The function of cytoplasmic CD32 is not known. These flow cytometric studies were cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3722083ee49b234246a49eb279894838
https://doi.org/10.1111/j.1365-2567.1997.00427.x
https://doi.org/10.1111/j.1365-2567.1997.00427.x
Publikováno v:
Rheumatology International. 11:235-241
We showed by immunofluorescence, immunoelectron microscopy and Western blot analysis that the plasma glycoprotein (gp60), an Fc gamma binding protein which inhibits complement-mediated prevention of immune precipitation, is present in platelets. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487462efc2b5f1d8c2b08fe593e58103
https://doi.org/10.1007/bf00301500
https://doi.org/10.1007/bf00301500
In this study we compared cell surface staining for human peripheral blood lymphocyte (PBL) CD antigens by flow cytometry, with staining obtained following permeabilization of PBL using the Cytoperm method (Serotec). Six CD antigens (CD20, CD21, CD22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00500fb69fe943cd2e1c2a66d1ed0da5
https://europepmc.org/articles/PMC2326768/
https://europepmc.org/articles/PMC2326768/
Publikováno v:
Immunology. 86(4)
Three main classes of Fc gamma receptor (Fc gamma R) have been described on the surface of normal human peripheral blood peripheral blood mononuclear cells. These receptors are thought to play an important role in many immune mechanisms. Following in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee5d87a66d71583491525e51e61c1e81
https://pubmed.ncbi.nlm.nih.gov/8567016
https://pubmed.ncbi.nlm.nih.gov/8567016
Publikováno v:
Immunology. 70(3)
Using various immunocytochemical techniques it has been shown that glycoprotein 60 (gp60), an IgG Fc-binding protein recently isolated from normal human plasma, is found localized in human hepatocytes, platelets and a subpopulation of normal peripher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bc09026922f58dfcb9be39d23e82dba
https://pubmed.ncbi.nlm.nih.gov/2143168
https://pubmed.ncbi.nlm.nih.gov/2143168