Zobrazeno 1 - 10
of 165
pro vyhledávání: '"G P Raaphorst"'
Autor:
Elwood P. Armour, G. P. Raaphorst
Publikováno v:
International Journal of Hyperthermia. 20:175-189
Combining long duration mild temperature hyperthermia (LDMH) and low dose-rate (LDR) brachytherapy to enhance therapeutic killing of cancer cells was proposed many years ago. The cellular and tumour research that supports this hypothesis is presented
Publikováno v:
Radiation Research. 161:215-218
Raaphorst, G. P., Maude-Leblanc, J. and Li, L. Evaluation of Recombination Repair Pathways in Thermal Radiosensitization. Radiat. Res. 161, 215–218 (2004). Thermal radiosensitization has been shown to cause inhibition of repair of sublethal and pot
Autor:
D M Smith, G P Raaphorst
Publikováno v:
International Journal of Radiation Biology. 79:333-339
Purpose: Human gliomas are known to be radioresistant and the aim was to determine if this resistance in part could be due to an adaptive response.Materials and methods: Human U‐87MG glioma cells were used. Three different radiation regimens that c
Autor:
H. E. Abbott Howley, G. P. Raaphorst
Publikováno v:
International Journal of Radiation Biology. 78:1095-1102
The difference in radiosensitivity between two isogenic tumour cell lines was evaluated to determine whether factors such as sublethal and potentially damage repair, DNA double-strand break repair and fidelity of repair can be related to differences
Publikováno v:
International Journal of Hyperthermia. 17:536-544
To determine whether pulsed dose rate irradiation in combination with mild hyperthermia could radiosensitize cells in comparison to pulsed dose rate irradiation alone, human ovarian carcinoma (A2780s, cisplatin- and radiation-sensitive, and A2780cp,
Publikováno v:
International Journal of Cancer. 90:336-342
The radiation responses of fibroblasts taken from four patients undergoing radiotherapy for prostate cancer were evaluated in vitro. One patient exhibited a severe normal tissue late reaction after radiotherapy, and the fibroblasts from this patient
Publikováno v:
Mutation Research/DNA Repair. 433:127-136
Cis -diamminedichloroplatinum II (cisplatin) is a DNA inter- and intrastrand crosslinking agent which can sensitize prokaryotic and eukaryotic cells to killing by ionizing radiation. The mechanism of radiosensitization is unknown but may involve cisp
Publikováno v:
International Journal of Radiation Biology. 75:1365-1376
To investigate the factors contributing to the in vitro radiosensitivity of four human pancreatic adenocarcinoma cell lines differing in p53 status, and the basis for the lack of post-irradiation G1 arrest in the two cell lines that have retained a w
Publikováno v:
International Journal of Radiation Biology. 75:837-846
To study retrospectively the relationship between intrinsic radiosensitivity (SF2), and both the low-dose inducible response (alpha(s)/alpha(r)) and the amount of split-dose recovery (betaRR).A total of 53 sets of experimental data obtained with 44 h
Publikováno v:
International Journal of Hyperthermia. 15:17-27
Human melanoma cells (SK-mel-3) were treated with combinations of radiation and hyperthermia treatment and survival (using the colony forming assay) and DNA double strand breaks (dsb's) (using pulsed field gel electrophoresis) were measured for immed