Zobrazeno 1 - 5
of 5
pro vyhledávání: '"G P Doherty"'
Autor:
G. H. Doherty
Publikováno v:
Current Gerontology and Geriatrics Research, Vol 2011 (2011)
Obesity and ageing are both characteristics of the human population that are on the increase across the globe. It has long been established that ageing is the major risk factor for neurodegenerative conditions such as Alzheimer's disease, and it is b
Externí odkaz:
https://doaj.org/article/13ff4e786e8d4bd4bf5aa7163fcfdfb2
Publikováno v:
British Journal of Cancer
DT-diaphorase is a two-electron-reducing enzyme that is an important activator of bioreductive anti-tumour agents, such as mitomycin C (MMC) and EO9, and is inducible by many compounds, including 1,2-dithiole-3-thiones (D3Ts). We showed previously th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b112c6c534059b7f15bb83e1cade4ee
https://doi.org/10.1038/bjc.1998.209
https://doi.org/10.1038/bjc.1998.209
Publikováno v:
Biochemical pharmacology. 61(8)
NAD(P)H:(quinone acceptor)oxidoreductase (DT-diaphorase) is a two-electron reducing enzyme that activates bioreductive antitumor agents and is induced by a wide variety of compounds including 1,2-dithiole-3-thione (D3T). We investigated factors influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4956e9b6e6ef7ea50f16a264d70bf82
https://pubmed.ncbi.nlm.nih.gov/11286987
https://pubmed.ncbi.nlm.nih.gov/11286987
Publikováno v:
British Journal of Cancer
DT-diaphorase is a two-electron reducing enzyme that activates the bioreductive anti-tumour agent, mitomycin C (MMC). Cell lines having elevated levels of DT-diaphorase are generally more sensitive to MMC. We have shown that DT-diaphorase can be indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6b5fb0850206f60551ca2c53afd48f
https://pubmed.ncbi.nlm.nih.gov/10376975
https://pubmed.ncbi.nlm.nih.gov/10376975
Publikováno v:
Oncology research. 9(6-7)
DT-diaphorase (EC 1.6.99.2) is a flavoprotein that catalyses two-electron reduction of quinones, quinone imines, and nitrogen oxides. It is a Phase II detoxifying enzyme that can detoxify chemically reactive metabolites, and may be important in an ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f1af9ab307af0447bbec16bb8ba442f
https://pubmed.ncbi.nlm.nih.gov/9406243
https://pubmed.ncbi.nlm.nih.gov/9406243