Zobrazeno 1 - 10
of 78
pro vyhledávání: '"G P, Vogler"'
Autor:
Lynn R. Goldin, G. P. Vogler
Publikováno v:
Genetic Epidemiology. 9:61-66
Linkage analysis under the two-locus model and the admixture model was compared on pedigree data for a common disease stimulated under a model of genetic heterogeneity. The ascertainment of families was designed so that the samples had a large propor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba5c37cd191039ccf29fe11e19a99ab
https://doi.org/10.1002/gepi.1370090107
https://doi.org/10.1002/gepi.1370090107
Autor:
Nicholas J. Schork, G. P. Vogler
Publikováno v:
Genetic Epidemiology. 9:73-86
Overt computational constraints in the formation of mixed models for the analysis of large extended-pedigree quantitative trait data which allow one to reliably characterize and partition sources of variation resulting from a variety sources have pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459f99b97f0970f4f0693c53c837d6a1
https://doi.org/10.1002/gepi.1370090202
https://doi.org/10.1002/gepi.1370090202
Autor:
Lindon J. Eaves, G. P. Vogler, Kristian Tambs, Torbjørn Moum, Per G. Lund-Larsen, Jostein Holmen, Siri Naess, Michael C. Neale
Publikováno v:
Genetic Epidemiology. 9:11-26
Systolic (SBP) and diastolic (DBP) blood pressures were measured in a health screening of the adult population in Nord-Trondelag, Norway. Correlations were computed for 23,936 pairs of spouses, 43,586 pairs of parent and offspring, 19,151 pairs of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31d304ff9deadba91227ce388b96dfb
https://doi.org/10.1002/gepi.1370090104
https://doi.org/10.1002/gepi.1370090104
Publikováno v:
Genetic Epidemiology. 9:177-184
In an effort to determine if structural variation in proteins important in bone metabolism might influence bone mineral density (BMD) and thus be a determinant of susceptibility to osteoporosis in older women, the authors typed a group of 258 non-Bla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc89ef679f9ae9b700f5c1b29302533
https://doi.org/10.1002/gepi.1370090304
https://doi.org/10.1002/gepi.1370090304
Publikováno v:
Genetic Epidemiology. 9:1-10
The frequency of restriction fragment length polymorphisms (RFLPs) of the apolipoprotein B (apo B) gene, detected by XbaI and EcoRI, and their influence on serum lipids and apolipoproteins were studied in healthy Chinese of both sexes in Singapore. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a27518c828a2f299f84526330f35e0b
https://doi.org/10.1002/gepi.1370090103
https://doi.org/10.1002/gepi.1370090103
Publikováno v:
Genetic Epidemiology. 9:67-71
Paternity exclusions are known to be common in Western countries and are yet neglected in segregation analysis because it is almost impossible to check it systematically on a large family sample. We had the opportunity of observing the sensitivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b74c99eeb2a792a86f030e42c9628a8
https://doi.org/10.1002/gepi.1370090108
https://doi.org/10.1002/gepi.1370090108
Publikováno v:
Genetic Epidemiology. 9:45-59
When a disease is controlled by two or more mendelian loci acting epistatically, it can be modeled in a linkage analysis as a single-locus mendelian disease with reduced penetrance. However, the reliability of such an approximation has not yet been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84efd8dc5ec7edd2854c21237b7001d6
https://doi.org/10.1002/gepi.1370090106
https://doi.org/10.1002/gepi.1370090106
Publikováno v:
Genetic Epidemiology. 9:155-167
Apolipoprotein E (apoE) phenotypes were determined in a random sample of 466 Danish men born in 1948. The frequencies of the common alleles of the apoE gene were (with 95% confidence intervals) epsilon 2 = 0.085 (0.068-0.105), epsilon 3 = 0.741 (0.71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce69fa77d494d4eaf6eabe033b7adcc3
https://doi.org/10.1002/gepi.1370090302
https://doi.org/10.1002/gepi.1370090302
Publikováno v:
Genetic Epidemiology. 9:123-139
In planning for a linkage study, it is important to determine the number of pedigrees needed to show linkage. Our study overcomes some of the limitations of previous power studies by simulating multigeneration pedigrees to be compatible with the demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2933c88d1e0bcd9dd84ac058d5659b38
https://doi.org/10.1002/gepi.1370090205
https://doi.org/10.1002/gepi.1370090205
Publikováno v:
Genetic Epidemiology. 9:27-44
Stimulated by a large pedigree with a cochlear form of deafness, for which we considered a two-locus mitochondrial and nuclear gene model, we have extended the classic methods of segregation analysis to these classes of two-locus disorders. Based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3600283db4be9f4c6d8031a6aea40bb0
https://doi.org/10.1002/gepi.1370090105
https://doi.org/10.1002/gepi.1370090105